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Jens Eklöf took his M.Sc.Eng. at the Royal Institute of Technology (KTH) and did his Ph.D. with Harry Brumer at the department of Glycoscience, KTH. His main focus areas are enzymes acting on the plant polysaccharide xyloglucan with special emphasis on the plant xth-gene product family of GH16. He has also been working with pectin methylesterases from Carbohydrate family 8 (CE8). His Ph. D. thesis entitled, "Plant and microbial xyloglucanses: Function, Structure and Phylogeny" can be accessed by clicking here.

He is currently working as a post doc in Vancouver, Canada in Harry Brumer's group.

Reference list

1. Eklöf JM and Brumer H. The XTH gene family: an update on enzyme structure, function, and phylogeny in xyloglucan remodeling. Plant Physiol 2010 Jun; 153(2) 456-66. doi:10.1104/pp.110.156844 pmid:20421457. PubMed HubMed [Eklof2010]
2. Eklöf JM, Tan TC, Divne C, and Brumer H. The crystal structure of the outer membrane lipoprotein YbhC from Escherichia coli sheds new light on the phylogeny of carbohydrate esterase family 8. Proteins 2009 Sep; 76(4) 1029-36. doi:10.1002/prot.22453 pmid:19452549. PubMed HubMed [Eklof2009]
3. Baumann MJ, Eklöf JM, Michel G, Kallas AM, Teeri TT, Czjzek M, and Brumer H 3rd. Structural evidence for the evolution of xyloglucanase activity from xyloglucan endo-transglycosylases: biological implications for cell wall metabolism. Plant Cell 2007 Jun; 19(6) 1947-63. doi:10.1105/tpc.107.051391 pmid:17557806. PubMed HubMed [Baumann2007]
4. Ariza A, Eklöf JM, Spadiut O, Offen WA, Roberts SM, Besenmatter W, Friis EP, Skjøt M, Wilson KS, Brumer H, and Davies G. Structure and activity of Paenibacillus polymyxa xyloglucanase from glycoside hydrolase family 44. J Biol Chem 2011 Sep 30; 286(39) 33890-900. doi:10.1074/jbc.M111.262345 pmid:21795708. PubMed HubMed [Ariza2011]
5. Mark P, Baumann MJ, Eklöf JM, Gullfot F, Michel G, Kallas AM, Teeri TT, Brumer H, and Czjzek M. Analysis of nasturtium TmNXG1 complexes by crystallography and molecular dynamics provides detailed insight into substrate recognition by family GH16 xyloglucan endo-transglycosylases and endo-hydrolases. Proteins 2009 Jun; 75(4) 820-36. doi:10.1002/prot.22291 pmid:19004021. PubMed HubMed [Mark2009]
6. Nordgren N, Eklöf J, Zhou Q, Brumer H 3rd, and Rutland MW. Top-down grafting of xyloglucan to gold monitored by QCM-D and AFM: enzymatic activity and interactions with cellulose. Biomacromolecules 2008 Mar; 9(3) 942-8. doi:10.1021/bm701214e pmid:18260631. PubMed HubMed [Nordgren2008]
7. Gloster TM, Ibatullin FM, Macauley K, Eklöf JM, Roberts S, Turkenburg JP, Bjørnvad ME, Jørgensen PL, Danielsen S, Johansen KS, Borchert TV, Wilson KS, Brumer H, and Davies GJ. Characterization and three-dimensional structures of two distinct bacterial xyloglucanases from families GH5 and GH12. J Biol Chem 2007 Jun 29; 282(26) 19177-89. doi:10.1074/jbc.M700224200 pmid:17376777. PubMed HubMed [Gloster2007]