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Difference between revisions of "Carbohydrate Esterase Families"
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As described in the CAZy database [http://www.cazy.org/Carbohydrate-Esterases.html CE familes page header]: <blockquote>"Carbohydrate esterases [also formally including carbohydrate amidases] catalyze the de-''O'' or de-''N''-acylation of substituted saccharides. Since an ester = acid + alcohol, we consider two classes of substrates for carbohydrate esterases: those in which the sugar plays the role of the "acid", such as pectin methyl esters and those in which the sugar behaves as the alcohol, such as in acetylated xylan. A number of possible reaction mechanisms may be involved: the most common is a Ser-His-Asp catalytic triad catalyzed deacetylation analogous to the action of classical lipase and serine proteases but other mechanisms such as a Zn<sup>2+</sup> catalyzed deacetylation prevails in some families."</blockquote> | As described in the CAZy database [http://www.cazy.org/Carbohydrate-Esterases.html CE familes page header]: <blockquote>"Carbohydrate esterases [also formally including carbohydrate amidases] catalyze the de-''O'' or de-''N''-acylation of substituted saccharides. Since an ester = acid + alcohol, we consider two classes of substrates for carbohydrate esterases: those in which the sugar plays the role of the "acid", such as pectin methyl esters and those in which the sugar behaves as the alcohol, such as in acetylated xylan. A number of possible reaction mechanisms may be involved: the most common is a Ser-His-Asp catalytic triad catalyzed deacetylation analogous to the action of classical lipase and serine proteases but other mechanisms such as a Zn<sup>2+</sup> catalyzed deacetylation prevails in some families."</blockquote> | ||
| − | The following reviews provide a useful overview to this class of CAZymes: <cite>Davies2005 Biely2012</cite>. | + | The following reviews together provide a useful overview to this class of CAZymes: <cite>Davies2005 Biely2012</cite>. |
== Curator Approved == | == Curator Approved == | ||
Revision as of 11:30, 31 May 2018
This page lists all the Carbohydrate Esterase (CE) Family pages in CAZypedia that have been given Curator Approved status, as well as those that are currently under construction.
Overview
As described in the CAZy database CE familes page header:
"Carbohydrate esterases [also formally including carbohydrate amidases] catalyze the de-O or de-N-acylation of substituted saccharides. Since an ester = acid + alcohol, we consider two classes of substrates for carbohydrate esterases: those in which the sugar plays the role of the "acid", such as pectin methyl esters and those in which the sugar behaves as the alcohol, such as in acetylated xylan. A number of possible reaction mechanisms may be involved: the most common is a Ser-His-Asp catalytic triad catalyzed deacetylation analogous to the action of classical lipase and serine proteases but other mechanisms such as a Zn2+ catalyzed deacetylation prevails in some families."
The following reviews together provide a useful overview to this class of CAZymes: [1, 2].
Curator Approved
These pages have been approved by the Responsible Curator as essentially complete. CAZypedia is a living document, so further improvement of these pages is still possible; please see the individual pages for more information.
There are currently 8 Curator approved Carbohydrate Esterase (CE) Family pages in CAZypedia.
Under construction
These pages are currently under construction in CAZypedia. As such, the Responsible Curator has deemed that the page's content is not quite up to CAZypedia's standards for full public consumption. All information on these pages should therefore be considered to be under revision and may be subject to major changes.
There are currently 3 Carbohydrate Esterase Family pages Under construction in CAZypedia.
Unassigned pages
The following Unassigned pages are currently lacking a Responsible Curator and one or more Authors. If you are an expert on any of these families and would like to help us improve CAZypedia by getting involved with the production and maintenance of the corresponding page(s), please contact a member of the Board of Curators directly, or via this form.
There are currently 8 Carbohydrate Esterase Family pages in CAZypedia that have not been assigned to a Responsible Curator.
- Carbohydrate Esterase Family 5
- Carbohydrate Esterase Family 8
- Carbohydrate Esterase Family 11
- Carbohydrate Esterase Family 12
- Carbohydrate Esterase Family 13
- Carbohydrate Esterase Family 14
- Carbohydrate Esterase Family 16
- Carbohydrate Esterase Family 17
References
- Davies GJ, Gloster TM, and Henrissat B. (2005). Recent structural insights into the expanding world of carbohydrate-active enzymes. Curr Opin Struct Biol. 2005;15(6):637-45. DOI:10.1016/j.sbi.2005.10.008 |
- Biely P (2012). Microbial carbohydrate esterases deacetylating plant polysaccharides. Biotechnol Adv. 2012;30(6):1575-88. DOI:10.1016/j.biotechadv.2012.04.010 |