CAZypedia needs your help! We have many unassigned GH, PL, CE, AA, GT, and CBM pages in need of Authors and Responsible Curators.
Scientists at all career stages, including students, are welcome to contribute to CAZypedia. Read more here, and in the 10th anniversary article in Glycobiology.
New to the CAZy classification? Read this first.
*
Consider attending the 15th Carbohydrate Bioengineering Meeting in Ghent, 5-8 May 2024.

Difference between revisions of "Template:News"

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'''9 September 2014:'''  ''2-for-1 Back to School Special:'' With the start of the new academic year, we are happy to report that two new [[Polysaccharide Lyase Families|Polysaccharide Lyase Family]] pages have recently been completed and given [[Curator Approved]] status.  In August, '''[[User:Naotake Konno|Naotake Konno]]''' and '''[[User:Shinya Fushinobu|Shinya Fushinobu]]''' produced the '''[[Polysaccharide Lyase Family 20]]''' page, which describes this small (currently, 18 member) group of bacterial and fungal beta-(1-4)-glucuronan-cleaving enzymes. ''And'', on the 7th of this month, '''[[User:Sine Larsen|Sine Larsen]]''' and '''[[User:Leila LoLeggio|Leila LoLeggio]]''' composed the '''[[Polysaccharide Lyase Family 4]]''' page.  Currently, '''[[PL4]]''' is only known to contain rhamnogalacturonan lyases involved in pectin degradation, notably including many plant sequences in addition to bacterial and fungal members.  We thank these [[Author]]s and [[Responsible Curator]]s for their contributions and encourage our readers to check out these new pages.
 
'''9 September 2014:'''  ''2-for-1 Back to School Special:'' With the start of the new academic year, we are happy to report that two new [[Polysaccharide Lyase Families|Polysaccharide Lyase Family]] pages have recently been completed and given [[Curator Approved]] status.  In August, '''[[User:Naotake Konno|Naotake Konno]]''' and '''[[User:Shinya Fushinobu|Shinya Fushinobu]]''' produced the '''[[Polysaccharide Lyase Family 20]]''' page, which describes this small (currently, 18 member) group of bacterial and fungal beta-(1-4)-glucuronan-cleaving enzymes. ''And'', on the 7th of this month, '''[[User:Sine Larsen|Sine Larsen]]''' and '''[[User:Leila LoLeggio|Leila LoLeggio]]''' composed the '''[[Polysaccharide Lyase Family 4]]''' page.  Currently, '''[[PL4]]''' is only known to contain rhamnogalacturonan lyases involved in pectin degradation, notably including many plant sequences in addition to bacterial and fungal members.  We thank these [[Author]]s and [[Responsible Curator]]s for their contributions and encourage our readers to check out these new pages.
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'''2 July 2014:''' ''More on the alpha-amylase clan:'' We are pleased to report that '''[[User:Stefan Janecek|Stefan Janecek]]''' has made another key contribution to ''CAZypedia'' by completing the '''[[Glycoside Hydrolase Family 77]]''' page today.  '''[[GH77]]''' contains enzymes variously known as ''amylomaltases'', ''4-α-glucanotransferases'', or ''disproportionating enzymes'' (''D-enzymes'' in plants), which catalyze (1-4)-to-(1-4) transglycosylation of alpha-glucan chains and form part of the starch/glycogen debranching system.  Together with [[GH13]] and [[GH70]], [[GH77]] constitutes [[Clan]] GH-H, a clan of alpha-glucan-specific enzymes united by a common (β/α)<sub>8</sub> catalytic domain fold.  [[User:Stefan Janecek|Stefan]] is the founder and main organiser of ''ALAMY'' - the international symposia on the alpha-amylase enzyme family -  and has been a key person in producing the [[GH13]], [[GH70]], [[GH77]] pages in ''CAZypedia''; we are especially grateful for all his hard work and expertise!
 
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'''23 June 2014:'''
 
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''"LysM" domains in CAZypedia:'' The cohort of [[Carbohydrate Binding Module Families]] covered in ''CAZypedia'' continues to grow with the completion of the '''[[Carbohydrate Binding Module Family 50]]''' by '''[[User:Takayuki Ohnuma|Takayuki Ohnuma]]''' and '''[[User:Toki Taira|Toki Taira]]'''.  [[CBM50]] members are also known as LysM domains, which are found in a range of enzymes beyond glycoside hydrolases, including proteases, in which they are believed to facilitate targeting and degradation the bacterial cell wall. ''Read more [[Carbohydrate Binding Module Family 50|here...!]]''
 
 
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Revision as of 16:46, 23 January 2015

7 January 2015: Love your guts: CAZypedia is ringing in the new year with a new Glycoside Hydrolase Family 76 page by Spencer Williams. GH76 contains endo-acting α-mannanases, including members from the human gut bacterium Bacteroides thetaiotaomicron that enable us to degrade yeast mannans in our diet. A very recent publication in Nature, notably involving CAZypedia contributors Michael Suits, Al Boraston, Spencer Williams, Gideon Davies, Wade Abbott, and Harry Gilbert, has recently shed new light on the structure, mechanism, and biological function of these enzymes. Read more here!

11 September 2014: Another PL family done: Today, Richard McLean and Wade Abbott finished the Polysaccharide Lyase Family 22 page, bringing the number of Curator Approved PL pages in CAZypedia to a total of 5 (of 23). PL22 is a family of bacterial (and a handful of archeal) oligogalacturonide lyases (OGLs), archetypal members of which are highly specific for digalacturonate and Δ4,5-unsaturated digalacturonate i.e., they do not cleave polymeric α-(1,4)-linked galacturonan, a component of pectin. Wade performed a seminal crystallographic analysis of PL22, and he and Richard have produced a lucid distillation of the mechanism of catalysis in this family. Read more here!

9 September 2014: 2-for-1 Back to School Special: With the start of the new academic year, we are happy to report that two new Polysaccharide Lyase Family pages have recently been completed and given Curator Approved status. In August, Naotake Konno and Shinya Fushinobu produced the Polysaccharide Lyase Family 20 page, which describes this small (currently, 18 member) group of bacterial and fungal beta-(1-4)-glucuronan-cleaving enzymes. And, on the 7th of this month, Sine Larsen and Leila LoLeggio composed the Polysaccharide Lyase Family 4 page. Currently, PL4 is only known to contain rhamnogalacturonan lyases involved in pectin degradation, notably including many plant sequences in addition to bacterial and fungal members. We thank these Authors and Responsible Curators for their contributions and encourage our readers to check out these new pages.

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