CAZypedia needs your help! We have many unassigned GH, PL, CE, AA, GT, and CBM pages in need of Authors and Responsible Curators.
Scientists at all career stages, including students, are welcome to contribute to CAZypedia. Read more here, and in the 10th anniversary article in Glycobiology.
New to the CAZy classification? Read this first.
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Consider attending the 15th Carbohydrate Bioengineering Meeting in Ghent, 5-8 May 2024.
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| + | '''17 January 2014:''' ''More on CBMs:'' The '''[[Carbohydrate Binding Module Family 41]]''' page was upgraded to [[Curator Approved]] status today by '''[[User:Alicia Lammerts van Bueren|Alicia Lammerts van Bueren]]''' and '''[[User:Al Boraston|Al Boraston]]'''. '''[[CBM41]]''' is a family of alpha-glucan-binfing modules, which are primarily associated with the pullulanases and amylases of [[Glycoside Hydrolase Family 13]]. ''Find out more [[Carbohydrate Binding Module Family 41|here...!]]'' | ||
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'''6 January 2014:''' ''A new year, a new CBM page!'' The '''[[Carbohydrate Binding Module Family 6]]''' page was completed and given [[Curator Approved]] status today by [[Author]] and [[Responsible Curator|Curator]] '''[[User:Mirjam Czjzek|Mirjam Czjzek]]'''. '''[[CBM6]]''' was originally defined based on the observation of xylan binding, however the diversity of substrate specificities in this family has now grown to include diverse beta-glucans, chitin, and even the marine polysaccharide agarose; remarkably, some '''[[CBM6]]''' members also contain two distinct binding sites. The '''[[CBM6]]''' page is ''CAZypedia's'' second [[Carbohydrate Binding Module Families|Carbohydrate Binding Module Family]] page, and we [[Carbohydrate_Binding_Module_Families#Under_construction|look forward]] to the further expansion of this section in the new year! | '''6 January 2014:''' ''A new year, a new CBM page!'' The '''[[Carbohydrate Binding Module Family 6]]''' page was completed and given [[Curator Approved]] status today by [[Author]] and [[Responsible Curator|Curator]] '''[[User:Mirjam Czjzek|Mirjam Czjzek]]'''. '''[[CBM6]]''' was originally defined based on the observation of xylan binding, however the diversity of substrate specificities in this family has now grown to include diverse beta-glucans, chitin, and even the marine polysaccharide agarose; remarkably, some '''[[CBM6]]''' members also contain two distinct binding sites. The '''[[CBM6]]''' page is ''CAZypedia's'' second [[Carbohydrate Binding Module Families|Carbohydrate Binding Module Family]] page, and we [[Carbohydrate_Binding_Module_Families#Under_construction|look forward]] to the further expansion of this section in the new year! | ||
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Revision as of 18:06, 19 January 2014
17 January 2014: More on CBMs: The Carbohydrate Binding Module Family 41 page was upgraded to Curator Approved status today by Alicia Lammerts van Bueren and Al Boraston. CBM41 is a family of alpha-glucan-binfing modules, which are primarily associated with the pullulanases and amylases of Glycoside Hydrolase Family 13. Find out more here...!
6 January 2014: A new year, a new CBM page! The Carbohydrate Binding Module Family 6 page was completed and given Curator Approved status today by Author and Curator Mirjam Czjzek. CBM6 was originally defined based on the observation of xylan binding, however the diversity of substrate specificities in this family has now grown to include diverse beta-glucans, chitin, and even the marine polysaccharide agarose; remarkably, some CBM6 members also contain two distinct binding sites. The CBM6 page is CAZypedia's second Carbohydrate Binding Module Family page, and we look forward to the further expansion of this section in the new year!
18 December 2013: A new mannanase page: Today, Rohan Williams and Spencer Williams completed the Glycoside Hydrolase Family 113 page. GH113 is currently a very small family (120 members) with only one characterized member, the Alicyclobacillus acidocaldarius beta(1-4)-mannanase. The seminal crystal structure of this enzyme revealed GH113 to be a member of Clan GH-A. A recent publication from the Williams team and collaborators illuminated further details of the GH113 and GH26 transition states using designed inhibitor-enzyme complexes. Read more about this emerging family here!
New for fall 2013: The CAZy database now presents enzyme ligands! See any family's "Structure" page for examples.
6 October 2013: GH66 page upgraded to Curator Approved status: Today, Responsible Curator Zui Fujimoto formally approved the Glycoside Hydrolase Family 66 page, Authored by Ryuichiro Suzuki, as complete and ready for public viewing. GH66 is a very small family, currently containing ca. 60 members, of α(1-6)-glucan hydrolases (a.k.a. dextranases) and cyclo-isomalto-oligosaccharide glucanotransferases. Through a series of elegant studies including biochemical and crystallographic analyses, Dr. Fujimoto and his collaborators have provided direct insight into catalysis by this unique family. Read more about the long history of these enzymes here!
30 September 2013: Our first PL page!: Wade Abbott finalized CAZypedia's first Polysaccharide Lyase Family page, PL2, today. As with our recent foray into CBM families (see our May 22 news item) the extension of CAZypedia to include the PLs ushers in a new phase in our development, and we are very much looking forward to the evolution of this new group of pages, spearheaded by Wade Abbott and Michael Suits. If you are an expert on any of the 22 PL families in the CAZy Database and would like to contribute to CAZypedia, please contact us here.