Carbohydrate-active enzymes - Revision history

Harry Brumer at 19:28, 4 July 2023

2023-07-04T19:28:31Z

Harry Brumer at 16:30, 20 April 2023

2023-04-20T16:30:47Z

Harry Brumer: added latest CAZy DB ref.

2023-04-20T16:30:23Z

added latest CAZy DB ref.

Harry Brumer: Text replacement - "User:Stephen Withers" to "User:Steve Withers"

2021-12-20T22:10:40Z

Text replacement - "User:Stephen Withers" to "User:Steve Withers"

Harry Brumer: Text replacement - "\^\^\^(.*)\^\^\^" to "$1"

2021-12-18T21:19:43Z

Text replacement - "\^\^\^(.*)\^\^\^" to "$1"

Harry Brumer: Fixed broken link to Sorting the Diverse - new DOI link added

2020-04-19T01:11:06Z

Fixed broken link to Sorting the Diverse - new DOI link added

Harry Brumer at 18:25, 31 May 2018

2018-05-31T18:25:22Z

Harry Brumer: /* The Carbohydrate Active EnZyme ("CAZy") classification */

2018-05-31T18:24:28Z

The Carbohydrate Active EnZyme ("CAZy") classification

Harry Brumer: fixed broken Garron + Cygler reference

2016-12-02T22:56:32Z

fixed broken Garron + Cygler reference

Harry Brumer at 18:32, 3 August 2016

2016-08-03T18:32:19Z

@@ Line 26: / Line 26: @@
 #Henrissat1996 pmid=8687420
 #DaviesHenrissat1995 pmid=8535779
-#DaviesSinnott2008 Davies, G.J. and Sinnott, M.L. (2008) Sorting the diverse: the sequence-based classifications of carbohydrate-active enzymes. ''The Biochemist'', vol. 30, no. 4., pp. 26-32. [https://doi.org/10.1042/BIO03004026 Download PDF version].
+#DaviesSinnott2008 Davies, G.J. and Sinnott, M.L. (2008) Sorting the diverse: the sequence-based classifications of carbohydrate-active enzymes. ''The Biochemist'', vol. 30, no. 4., pp. 26-32. [https://doi.org/10.1042/BIO03004026 DOI:10.1042/BIO03004026].
 #Cantarel2009 pmid=18838391
 #Lombard2013 pmid=24270786

@@ Line 7: / Line 7: @@
 ==The <U>C</U>arbohydrate <U>A</U>ctive En<U>Zy</U>me ("CAZy") classification==
-The <U>C</U>arbohydrate <U>A</U>ctive En<U>Zy</U>me (CAZy) classification is a [[sequence-based classification]] of enzymes that synthesize or break-down saccharides, which originated with the seminal grouping of glycoside hydrolases by [[User:Bernard Henrissat|Bernard Henrissat]] (<cite>Henrissat1989 Henrissat1991 Henrissat1993 Henrissat1996</cite>; see <cite>DaviesSinnott2008</cite> for a lucid historical review). The creation of a family requires at least one biochemically-characterized member, and is based on the concept that sequence defines protein structure, and protein structure defines function. Generally, but not exclusively, functional properties often extend to other members of the family, and provides a framework upon which to base testable hypotheses of enzyme structure and function <cite>DaviesHenrissat1995</cite>.  Since its inception, the CAZy classification and associated database has undergone continually active curation, including the addition of new enzyme and associated module classes <cite>Cantarel2009 Lombard2013 Drula 2022</cite>.  Hence, the CAZy classification presently comprises the following modules:
+The <U>C</U>arbohydrate <U>A</U>ctive En<U>Zy</U>me (CAZy) classification is a [[sequence-based classification]] of enzymes that synthesize or break-down saccharides, which originated with the seminal grouping of glycoside hydrolases by [[User:Bernard Henrissat|Bernard Henrissat]] (<cite>Henrissat1989 Henrissat1991 Henrissat1993 Henrissat1996</cite>; see <cite>DaviesSinnott2008</cite> for a lucid historical review). The creation of a family requires at least one biochemically-characterized member, and is based on the concept that sequence defines protein structure, and protein structure defines function. Generally, but not exclusively, functional properties often extend to other members of the family, and provides a framework upon which to base testable hypotheses of enzyme structure and function <cite>DaviesHenrissat1995</cite>.  Since its inception, the CAZy classification and associated database has undergone continually active curation, including the addition of new enzyme and associated module classes <cite>Cantarel2009 Lombard2013 Drula2022</cite>.  Hence, the CAZy classification presently comprises the following modules:
 * [[Glycosyltransferase Families]] <cite>Campbell1997 Coutinho2003 Coutinho2009</cite>
 * [[Glycoside Hydrolase Families]] <cite>Henrissat1991 Henrissat1993 Henrissat1996</cite>

@@ Line 7: / Line 7: @@
 ==The <U>C</U>arbohydrate <U>A</U>ctive En<U>Zy</U>me ("CAZy") classification==
-The <U>C</U>arbohydrate <U>A</U>ctive En<U>Zy</U>me (CAZy) classification is a [[sequence-based classification]] of enzymes that synthesize or break-down saccharides, which originated with the seminal grouping of glycoside hydrolases by [[User:Bernard Henrissat|Bernard Henrissat]] (<cite>Henrissat1989 Henrissat1991 Henrissat1993 Henrissat1996</cite>; see <cite>DaviesSinnott2008</cite> for a lucid historical review). The creation of a family requires at least one biochemically-characterized member, and is based on the concept that sequence defines protein structure, and protein structure defines function. Generally, but not exclusively, functional properties often extend to other members of the family, and provides a framework upon which to base testable hypotheses of enzyme structure and function <cite>DaviesHenrissat1995</cite>.  Since its inception, the CAZy classification and associated database has undergone continually active curation, including the addition of new enzyme and associated module classes <cite>Cantarel2009 Lombard2013</cite>.  Hence, the CAZy classification presently comprises the following modules:
+The <U>C</U>arbohydrate <U>A</U>ctive En<U>Zy</U>me (CAZy) classification is a [[sequence-based classification]] of enzymes that synthesize or break-down saccharides, which originated with the seminal grouping of glycoside hydrolases by [[User:Bernard Henrissat|Bernard Henrissat]] (<cite>Henrissat1989 Henrissat1991 Henrissat1993 Henrissat1996</cite>; see <cite>DaviesSinnott2008</cite> for a lucid historical review). The creation of a family requires at least one biochemically-characterized member, and is based on the concept that sequence defines protein structure, and protein structure defines function. Generally, but not exclusively, functional properties often extend to other members of the family, and provides a framework upon which to base testable hypotheses of enzyme structure and function <cite>DaviesHenrissat1995</cite>.  Since its inception, the CAZy classification and associated database has undergone continually active curation, including the addition of new enzyme and associated module classes <cite>Cantarel2009 Lombard2013 Drula 2022</cite>.  Hence, the CAZy classification presently comprises the following modules:
 * [[Glycosyltransferase Families]] <cite>Campbell1997 Coutinho2003 Coutinho2009</cite>
 * [[Glycoside Hydrolase Families]] <cite>Henrissat1991 Henrissat1993 Henrissat1996</cite>
@@ Line 39: / Line 39: @@
 #Davies2005 pmid=16263268
 #Biely2012 pmid=22580218
 </biblio>
 [[Category:Definitions and explanations]]

@@ Line 1: / Line 1: @@
 {{CuratorApproved}}
-* [[Author]]s: [[User:Stephen Withers|Stephen Withers]], [[User:Spencer Williams|Spencer Williams]], and [[User:Harry Brumer|Harry Brumer]]
+* [[Author]]s: [[User:Steve Withers|Stephen Withers]], [[User:Spencer Williams|Spencer Williams]], and [[User:Harry Brumer|Harry Brumer]]
 * [[Responsible Curator]]:  [[User:Spencer Williams|Spencer Williams]]
 ----

@@ Line 1: / Line 1: @@
 {{CuratorApproved}}
-* [[Author]]s: ^^^Stephen Withers^^^, ^^^Spencer Williams^^^, and ^^^Harry Brumer^^^
+* [[Author]]s: [[User:Stephen Withers|Stephen Withers]], [[User:Spencer Williams|Spencer Williams]], and [[User:Harry Brumer|Harry Brumer]]
-* [[Responsible Curator]]:  ^^^Spencer Williams^^^
+* [[Responsible Curator]]:  [[User:Spencer Williams|Spencer Williams]]
 ----
@@ Line 7: / Line 7: @@
 ==The <U>C</U>arbohydrate <U>A</U>ctive En<U>Zy</U>me ("CAZy") classification==
-The <U>C</U>arbohydrate <U>A</U>ctive En<U>Zy</U>me (CAZy) classification is a [[sequence-based classification]] of enzymes that synthesize or break-down saccharides, which originated with the seminal grouping of glycoside hydrolases by ^^^Bernard Henrissat^^^ (<cite>Henrissat1989 Henrissat1991 Henrissat1993 Henrissat1996</cite>; see <cite>DaviesSinnott2008</cite> for a lucid historical review). The creation of a family requires at least one biochemically-characterized member, and is based on the concept that sequence defines protein structure, and protein structure defines function. Generally, but not exclusively, functional properties often extend to other members of the family, and provides a framework upon which to base testable hypotheses of enzyme structure and function <cite>DaviesHenrissat1995</cite>.  Since its inception, the CAZy classification and associated database has undergone continually active curation, including the addition of new enzyme and associated module classes <cite>Cantarel2009 Lombard2013</cite>.  Hence, the CAZy classification presently comprises the following modules:
+The <U>C</U>arbohydrate <U>A</U>ctive En<U>Zy</U>me (CAZy) classification is a [[sequence-based classification]] of enzymes that synthesize or break-down saccharides, which originated with the seminal grouping of glycoside hydrolases by [[User:Bernard Henrissat|Bernard Henrissat]] (<cite>Henrissat1989 Henrissat1991 Henrissat1993 Henrissat1996</cite>; see <cite>DaviesSinnott2008</cite> for a lucid historical review). The creation of a family requires at least one biochemically-characterized member, and is based on the concept that sequence defines protein structure, and protein structure defines function. Generally, but not exclusively, functional properties often extend to other members of the family, and provides a framework upon which to base testable hypotheses of enzyme structure and function <cite>DaviesHenrissat1995</cite>.  Since its inception, the CAZy classification and associated database has undergone continually active curation, including the addition of new enzyme and associated module classes <cite>Cantarel2009 Lombard2013</cite>.  Hence, the CAZy classification presently comprises the following modules:
 * [[Glycosyltransferase Families]] <cite>Campbell1997 Coutinho2003 Coutinho2009</cite>
 * [[Glycoside Hydrolase Families]] <cite>Henrissat1991 Henrissat1993 Henrissat1996</cite>

@@ Line 11: / Line 11: @@
 * [[Glycoside Hydrolase Families]] <cite>Henrissat1991 Henrissat1993 Henrissat1996</cite>
 * [[Polysaccharide Lyase Families]] <cite>Lombard2010 Garron2010</cite>
-* [[Carbohydrate Esterase Families]] <<cite>Davies2005 Biely2012</cite>>
+* [[Carbohydrate Esterase Families]] <cite>Davies2005 Biely2012</cite>
 * [[Auxiliary Activity Families]] <cite>Levasseur2013</cite>
 * [[Carbohydrate Binding Module Families]] (non-catalytic; included due to their association with catalytic modules) <cite>Cantarel2009</cite>.
@@ Line 33: / Line 33: @@
 #Coutinho2003 pmid=12691742
 #Coutinho2009 isbn=9780470016671 // ''Chapter 5:'' Coutinho PM, Rancurel C, Stam M, Bernard T, Couto FM, Danchin EGJ, Henrissat B. "Carbohydrate-active Enzymes Database: Principles and Classification of Glycosyltransferases."
 #Garron2010 pmid=20805221
 #Levasseur2013 pmid=23514094
 #Henrissat1989 pmid=2806912
 #Sinnott2007 isbn=9780854042562
 </biblio>
 [[Category:Definitions and explanations]]