User:David Vocadlo - Revision history

Harry Brumer: Text replacement - "User:Stephen Withers" to "User:Steve Withers"

2021-12-20T22:10:40Z

Text replacement - "User:Stephen Withers" to "User:Steve Withers"

Harry Brumer: Text replacement - "\^\^\^(.*)\^\^\^" to "$1"

2021-12-18T21:35:13Z

Text replacement - "\^\^\^(.*)\^\^\^" to "$1"

Harry Brumer at 18:34, 29 August 2013

2013-08-29T18:34:47Z

David Vocadlo at 17:01, 29 August 2013

2013-08-29T17:01:48Z

David Vocadlo at 16:59, 29 August 2013

2013-08-29T16:59:06Z

David Vocadlo at 16:53, 29 August 2013

2013-08-29T16:53:00Z

Harry Brumer at 18:56, 17 November 2012

2012-11-17T18:56:22Z

Harry Brumer at 20:34, 15 February 2010

2010-02-15T20:34:18Z

David Vocadlo: Created page with 'hi this is '''''dave''''''

2010-02-15T16:23:44Z

Created page with 'hi this is '''''dave''''''

New page

hi this is '''''dave'''''

← Older revision		Revision as of 22:10, 20 December 2021
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−	I received my BSc degree in combined Chemistry and Biochemistry from the University of British Columbia (UBC, Vancouver, British Columbia, Canada). After considering a career in architecture I found experimental design and the construction of hypotheses to be more engaging. To pursue my particular interest in the remarkable catalytic proficiency of enzymes I joined the laboratory of [[User:~~Stephen~~ Withers\|Stephen Withers]] at UBC to pursue my PhD studies in Bioorganic Chemistry. While there I synthesized both substrates and inhibitors of retaining glycoside hydrolases and clarified the catalytic mechanism of hen egg white lysozyme (HEWL) <cite>Vocadlo2001</cite>, a member of [[GH22]]. My interests gradually turned to integrating knowledge of the mechanisms of glycan processing enzymes with their functions in cellular systems. To pursue this interest and exploit knowledge of the biochemistry of glycoside hydrolases and transferases to design chemical tools for use in studying glycans in cellular systems, I moved to the University of California at Berkeley (Berkeley, California, USA) to work with Carolyn Bertozzi. While there I developed chemical probes to perform functional proteomics of glycosylation within cellular systems. In 2004 I returned to Canada and joined Simon Fraser University (Burnaby, British Columbia, Canada) where I am now a Canada Research Chair in Chemical Glycobiology and professor in the Departments of Chemistry and Molecular Biology and Biochemistry. My current interests centre of developing and validating chemical tools that can be used to probe and perturb carbohydrates in cellular and organismal models. One particular interest in the laboratory is to improve our understanding of the physiological and pathophysiological roles of an intracellular form of protein glycosylation known as O-GlcNAc.	+	I received my BSc degree in combined Chemistry and Biochemistry from the University of British Columbia (UBC, Vancouver, British Columbia, Canada). After considering a career in architecture I found experimental design and the construction of hypotheses to be more engaging. To pursue my particular interest in the remarkable catalytic proficiency of enzymes I joined the laboratory of [[User:Steve Withers\|Stephen Withers]] at UBC to pursue my PhD studies in Bioorganic Chemistry. While there I synthesized both substrates and inhibitors of retaining glycoside hydrolases and clarified the catalytic mechanism of hen egg white lysozyme (HEWL) <cite>Vocadlo2001</cite>, a member of [[GH22]]. My interests gradually turned to integrating knowledge of the mechanisms of glycan processing enzymes with their functions in cellular systems. To pursue this interest and exploit knowledge of the biochemistry of glycoside hydrolases and transferases to design chemical tools for use in studying glycans in cellular systems, I moved to the University of California at Berkeley (Berkeley, California, USA) to work with Carolyn Bertozzi. While there I developed chemical probes to perform functional proteomics of glycosylation within cellular systems. In 2004 I returned to Canada and joined Simon Fraser University (Burnaby, British Columbia, Canada) where I am now a Canada Research Chair in Chemical Glycobiology and professor in the Departments of Chemistry and Molecular Biology and Biochemistry. My current interests centre of developing and validating chemical tools that can be used to probe and perturb carbohydrates in cellular and organismal models. One particular interest in the laboratory is to improve our understanding of the physiological and pathophysiological roles of an intracellular form of protein glycosylation known as O-GlcNAc.

	Please see [http://www.chemistry.sfu.ca/people/profiles/dvocadlo my Simon Fraser University page] for more details on my research interests.		Please see [http://www.chemistry.sfu.ca/people/profiles/dvocadlo my Simon Fraser University page] for more details on my research interests.

← Older revision		Revision as of 21:35, 18 December 2021
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−	I received my BSc degree in combined Chemistry and Biochemistry from the University of British Columbia (UBC, Vancouver, British Columbia, Canada). After considering a career in architecture I found experimental design and the construction of hypotheses to be more engaging. To pursue my particular interest in the remarkable catalytic proficiency of enzymes I joined the laboratory of ~~^^^~~Stephen Withers~~^^^~~ at UBC to pursue my PhD studies in Bioorganic Chemistry. While there I synthesized both substrates and inhibitors of retaining glycoside hydrolases and clarified the catalytic mechanism of hen egg white lysozyme (HEWL) <cite>Vocadlo2001</cite>, a member of [[GH22]]. My interests gradually turned to integrating knowledge of the mechanisms of glycan processing enzymes with their functions in cellular systems. To pursue this interest and exploit knowledge of the biochemistry of glycoside hydrolases and transferases to design chemical tools for use in studying glycans in cellular systems, I moved to the University of California at Berkeley (Berkeley, California, USA) to work with Carolyn Bertozzi. While there I developed chemical probes to perform functional proteomics of glycosylation within cellular systems. In 2004 I returned to Canada and joined Simon Fraser University (Burnaby, British Columbia, Canada) where I am now a Canada Research Chair in Chemical Glycobiology and professor in the Departments of Chemistry and Molecular Biology and Biochemistry. My current interests centre of developing and validating chemical tools that can be used to probe and perturb carbohydrates in cellular and organismal models. One particular interest in the laboratory is to improve our understanding of the physiological and pathophysiological roles of an intracellular form of protein glycosylation known as O-GlcNAc.	+	I received my BSc degree in combined Chemistry and Biochemistry from the University of British Columbia (UBC, Vancouver, British Columbia, Canada). After considering a career in architecture I found experimental design and the construction of hypotheses to be more engaging. To pursue my particular interest in the remarkable catalytic proficiency of enzymes I joined the laboratory of [[User:Stephen Withers\|Stephen Withers]] at UBC to pursue my PhD studies in Bioorganic Chemistry. While there I synthesized both substrates and inhibitors of retaining glycoside hydrolases and clarified the catalytic mechanism of hen egg white lysozyme (HEWL) <cite>Vocadlo2001</cite>, a member of [[GH22]]. My interests gradually turned to integrating knowledge of the mechanisms of glycan processing enzymes with their functions in cellular systems. To pursue this interest and exploit knowledge of the biochemistry of glycoside hydrolases and transferases to design chemical tools for use in studying glycans in cellular systems, I moved to the University of California at Berkeley (Berkeley, California, USA) to work with Carolyn Bertozzi. While there I developed chemical probes to perform functional proteomics of glycosylation within cellular systems. In 2004 I returned to Canada and joined Simon Fraser University (Burnaby, British Columbia, Canada) where I am now a Canada Research Chair in Chemical Glycobiology and professor in the Departments of Chemistry and Molecular Biology and Biochemistry. My current interests centre of developing and validating chemical tools that can be used to probe and perturb carbohydrates in cellular and organismal models. One particular interest in the laboratory is to improve our understanding of the physiological and pathophysiological roles of an intracellular form of protein glycosylation known as O-GlcNAc.

	Please see [http://www.chemistry.sfu.ca/people/profiles/dvocadlo my Simon Fraser University page] for more details on my research interests.		Please see [http://www.chemistry.sfu.ca/people/profiles/dvocadlo my Simon Fraser University page] for more details on my research interests.

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-I received his BSc degree in combined Chemistry and Biochemistry from the University of British Columbia (UBC, Vancouver, British Columbia, Canada). After considering a career in architecture I found experimental design and the construction of hypotheses to be more engaging. To pursue my particular interest in the remarkable catalytic proficiency of enzymes I joined the laboratory of Stephen Withers at UBC to pursue my PhD studies in Bioorganic Chemistry. While there I synthesized both substrates and inhibitors of retaining glycoside hydrolases and clarified the catalytic mechanism of hen egg white lysozyme (HEWL). My interests gradually turned to integrating knowledge of the mechanisms of glycan processing enzymes with their functions in cellular systems. To pursue this interest and exploit knowledge of the biochemistry of glycoside hydrolases and transferases to design chemical tools for use in studying glycans in cellular systems, I moved to the University of California at Berkeley (Berkeley, California, USA) to work with Carolyn Bertozzi. While there I developed chemical probes to perform functional proteomics of glycosylation within cellular systems. In 2004 I returned to Canada and joined Simon Fraser University (Burnaby, British Columbia, Canada) where I am now a Canada Research Chair in Chemical Glycobiology and professor in the Departments of Chemistry and Molecular Biology and Biochemistry. My current interests centre of developing and validating chemical tools that can be used to probe and perturb carbohydrates in cellular and organismal models. One particular interest in the laboratory is to improve our understanding of the physiological and pathophysiological roles of an intracellular form of protein glycosylation known as O-GlcNAc.
+I received my BSc degree in combined Chemistry and Biochemistry from the University of British Columbia (UBC, Vancouver, British Columbia, Canada). After considering a career in architecture I found experimental design and the construction of hypotheses to be more engaging. To pursue my particular interest in the remarkable catalytic proficiency of enzymes I joined the laboratory of ^^^Stephen Withers^^^ at UBC to pursue my PhD studies in Bioorganic Chemistry. While there I synthesized both substrates and inhibitors of retaining glycoside hydrolases and clarified the catalytic mechanism of hen egg white lysozyme (HEWL) <cite>Vocadlo2001</cite>, a member of [[GH22]]. My interests gradually turned to integrating knowledge of the mechanisms of glycan processing enzymes with their functions in cellular systems. To pursue this interest and exploit knowledge of the biochemistry of glycoside hydrolases and transferases to design chemical tools for use in studying glycans in cellular systems, I moved to the University of California at Berkeley (Berkeley, California, USA) to work with Carolyn Bertozzi. While there I developed chemical probes to perform functional proteomics of glycosylation within cellular systems. In 2004 I returned to Canada and joined Simon Fraser University (Burnaby, British Columbia, Canada) where I am now a Canada Research Chair in Chemical Glycobiology and professor in the Departments of Chemistry and Molecular Biology and Biochemistry. My current interests centre of developing and validating chemical tools that can be used to probe and perturb carbohydrates in cellular and organismal models. One particular interest in the laboratory is to improve our understanding of the physiological and pathophysiological roles of an intracellular form of protein glycosylation known as O-GlcNAc.
-Please see [http://www.chemistry.sfu.ca/people/profiles/dvocadlo David's Simon Fraser University page] for more details on my research interests.
+Please see [http://www.chemistry.sfu.ca/people/profiles/dvocadlo my Simon Fraser University page] for more details on my research interests.
 [[Category:Contributors|Vocadlo, David]]

← Older revision		Revision as of 17:01, 29 August 2013
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−	I received his BSc degree in combined Chemistry and Biochemistry from the University of British Columbia (UBC, Vancouver, British Columbia, Canada). After considering a career in architecture I found experimental design and the construction of hypotheses to be more engaging. To pursue my particular interest in the remarkable catalytic proficiency of enzymes I joined the laboratory of Stephen Withers at UBC to pursue my PhD studies in Bioorganic Chemistry. While there I synthesized both substrates and inhibitors of retaining glycoside hydrolases and clarified the catalytic mechanism of hen egg white lysozyme (HEWL). My interests gradually turned to integrating knowledge of the mechanisms of glycan processing enzymes with their functions in cellular systems. To pursue this interest ~~in integrating~~ knowledge of the biochemistry of glycoside hydrolases and transferases ~~with the~~ design ~~and use of~~ chemical tools ~~to study~~ glycans in cellular systems I moved to the University of California at Berkeley to work with Carolyn Bertozzi. While there I developed chemical probes to perform functional proteomics of glycosylation within cellular systems. In 2004 I returned to Canada and joined Simon Fraser University (Burnaby, British Columbia, Canada) where I am now a Canada Research Chair in Chemical Glycobiology and professor in the Departments of Chemistry and Molecular Biology and Biochemistry. My current interests centre of developing and validating chemical tools that can be used to probe and perturb carbohydrates in cellular and organismal models. One particular interest in the laboratory is to improve our understanding of the physiological and pathophysiological roles of an intracellular form of protein glycosylation known as O-GlcNAc.	+	I received his BSc degree in combined Chemistry and Biochemistry from the University of British Columbia (UBC, Vancouver, British Columbia, Canada). After considering a career in architecture I found experimental design and the construction of hypotheses to be more engaging. To pursue my particular interest in the remarkable catalytic proficiency of enzymes I joined the laboratory of Stephen Withers at UBC to pursue my PhD studies in Bioorganic Chemistry. While there I synthesized both substrates and inhibitors of retaining glycoside hydrolases and clarified the catalytic mechanism of hen egg white lysozyme (HEWL). My interests gradually turned to integrating knowledge of the mechanisms of glycan processing enzymes with their functions in cellular systems. To pursue this interest and exploit knowledge of the biochemistry of glycoside hydrolases and transferases to design chemical tools for use in studying glycans in cellular systems, I moved to the University of California at Berkeley (Berkeley, California, USA) to work with Carolyn Bertozzi. While there I developed chemical probes to perform functional proteomics of glycosylation within cellular systems. In 2004 I returned to Canada and joined Simon Fraser University (Burnaby, British Columbia, Canada) where I am now a Canada Research Chair in Chemical Glycobiology and professor in the Departments of Chemistry and Molecular Biology and Biochemistry. My current interests centre of developing and validating chemical tools that can be used to probe and perturb carbohydrates in cellular and organismal models. One particular interest in the laboratory is to improve our understanding of the physiological and pathophysiological roles of an intracellular form of protein glycosylation known as O-GlcNAc.

	Please see [http://www.chemistry.sfu.ca/people/profiles/dvocadlo David's Simon Fraser University page] for more details on my research interests.		Please see [http://www.chemistry.sfu.ca/people/profiles/dvocadlo David's Simon Fraser University page] for more details on my research interests.

← Older revision		Revision as of 16:59, 29 August 2013
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−	I received his BSc degree in combined Chemistry and Biochemistry from the University of British Columbia (UBC). After considering a career in architecture I found experimental design and the construction of hypotheses to be more engaging. To pursue my particular interest in the catalytic proficiency of enzymes I joined the laboratory of Stephen Withers at UBC to pursue my PhD studies in Bioorganic Chemistry. While there I synthesized substrates and inhibitors of retaining glycoside hydrolases and clarified the catalytic mechanism of hen egg white lysozyme (HEWL). My interests turned ~~at this time~~ to ~~eukaryotic~~ systems and ~~integrating~~ the use of chemical tools in cellular systems~~. To pursue these interests~~ I moved to the University of California at Berkeley to work with Carolyn Bertozzi~~, developing~~ chemical probes ~~for~~ functional proteomics of glycosylation in cellular systems. In 2004 he returned to Canada and joined Simon Fraser University where is now a Canada Research Chair in Chemical Glycobiology and professor in the Departments of Chemistry and Molecular Biology and Biochemistry. My current interests centre of developing and validating chemical tools that can be used to probe and perturb carbohydrates in cellular and organismal models. ~~A major focus~~ in the laboratory is to improve our understanding of the physiological and pathophysiological roles of an intracellular form of protein glycosylation known as O-GlcNAc.	+	I received his BSc degree in combined Chemistry and Biochemistry from the University of British Columbia (UBC, Vancouver, British Columbia, Canada). After considering a career in architecture I found experimental design and the construction of hypotheses to be more engaging. To pursue my particular interest in the remarkable catalytic proficiency of enzymes I joined the laboratory of Stephen Withers at UBC to pursue my PhD studies in Bioorganic Chemistry. While there I synthesized both substrates and inhibitors of retaining glycoside hydrolases and clarified the catalytic mechanism of hen egg white lysozyme (HEWL). My interests gradually turned to integrating knowledge of the mechanisms of glycan processing enzymes with their functions in cellular systems. To pursue this interest in integrating knowledge of the biochemistry of glycoside hydrolases and transferases with the design and use of chemical tools to study glycans in cellular systems I moved to the University of California at Berkeley to work with Carolyn Bertozzi. While there I developed chemical probes to perform functional proteomics of glycosylation within cellular systems. In 2004 I returned to Canada and joined Simon Fraser University (Burnaby, British Columbia, Canada) where I am now a Canada Research Chair in Chemical Glycobiology and professor in the Departments of Chemistry and Molecular Biology and Biochemistry. My current interests centre of developing and validating chemical tools that can be used to probe and perturb carbohydrates in cellular and organismal models. One particular interest in the laboratory is to improve our understanding of the physiological and pathophysiological roles of an intracellular form of protein glycosylation known as O-GlcNAc.

	Please see [http://www.chemistry.sfu.ca/people/profiles/dvocadlo David's Simon Fraser University page] for more details on my research interests.		Please see [http://www.chemistry.sfu.ca/people/profiles/dvocadlo David's Simon Fraser University page] for more details on my research interests.

← Older revision		Revision as of 16:53, 29 August 2013
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−	While this ~~page~~ is ~~under construction, please~~ see [http://www.chemistry.sfu.ca/people/profiles/dvocadlo David's Simon Fraser University page] for ~~his biographical information~~.	+
		+	I received his BSc degree in combined Chemistry and Biochemistry from the University of British Columbia (UBC). After considering a career in architecture I found experimental design and the construction of hypotheses to be more engaging. To pursue my particular interest in the catalytic proficiency of enzymes I joined the laboratory of Stephen Withers at UBC to pursue my PhD studies in Bioorganic Chemistry. While there I synthesized substrates and inhibitors of retaining glycoside hydrolases and clarified the catalytic mechanism of hen egg white lysozyme (HEWL). My interests turned at this time to eukaryotic systems and integrating the use of chemical tools in cellular systems. To pursue these interests I moved to the University of California at Berkeley to work with Carolyn Bertozzi, developing chemical probes for functional proteomics of glycosylation in cellular systems. In 2004 he returned to Canada and joined Simon Fraser University where is now a Canada Research Chair in Chemical Glycobiology and professor in the Departments of Chemistry and Molecular Biology and Biochemistry. My current interests centre of developing and validating chemical tools that can be used to probe and perturb carbohydrates in cellular and organismal models. A major focus in the laboratory is to improve our understanding of the physiological and pathophysiological roles of an intracellular form of protein glycosylation known as O-GlcNAc.
		+
		+	Please see [http://www.chemistry.sfu.ca/people/profiles/dvocadlo David's Simon Fraser University page] for more details on my research interests.


	[[Category:Contributors\|Vocadlo, David]]		[[Category:Contributors\|Vocadlo, David]]

← Older revision		Revision as of 18:56, 17 November 2012
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−	hi this is '~~''''dave'''''~~	+	While this page is under construction, please see [http://www.chemistry.sfu.ca/people/profiles/dvocadlo David's Simon Fraser University page] for his biographical information.


	[[Category:Contributors\|Vocadlo, David]]		[[Category:Contributors\|Vocadlo, David]]

← Older revision		Revision as of 20:34, 15 February 2010
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	hi this is '''''dave'''''		hi this is '''''dave'''''
		+
		+
		+	[[Category:Contributors\|Vocadlo, David]]