User:Finn Aachmann - Revision history

Harry Brumer: Text replacement - "\^\^\^(.*)\^\^\^" to "$1"

2021-12-18T21:34:18Z

Text replacement - "\^\^\^(.*)\^\^\^" to "$1"

Finn Aachmann at 19:22, 9 August 2020

2020-08-09T19:22:04Z

Finn Aachmann at 19:18, 9 August 2020

2020-08-09T19:18:30Z

Finn Aachmann at 19:12, 9 August 2020

2020-08-09T19:12:31Z

Finn Aachmann: /* References */

2020-08-09T19:07:58Z

References

Finn Aachmann: /* References */

2020-08-09T19:00:11Z

References

Finn Aachmann: /* References */

2020-08-09T18:59:50Z

References

Finn Aachmann at 18:42, 9 August 2020

2020-08-09T18:42:49Z

Finn Aachmann at 18:41, 9 August 2020

2020-08-09T18:41:45Z

Finn Aachmann at 18:40, 9 August 2020

2020-08-09T18:40:36Z

@@ Line 7: / Line 7: @@
 During my Post Doc at NTNU (2005-2007) I continued with structure elucidation and functional characterization on selenocysteine containing proteins using NMR spectroscopy under the supervision of Alex Dykyy at NTNU. Here I also had a key role in building up the NMR structure determination facilities at the NV-faculty NMR center NTNU and today I lead the NMR laboratory.
-I was recruited as senior scientist on structure elucidation of proteins and carbohydrates by NMR in NOBIPOL (The Norwegian Biopolymer Laboratory) at NTNU (2007-2016). During this period, we started a collaboration with ^^^Vincent Eijsink^^^ with focus on structure and functional determination of lytic polysaccharide monooxygenases (LPMO) with NMR <cite>aachmann2012,westereng2013,isaksen2014,courtade2016,courtade2018,courtade2020</cite>. Here we used NMR in many ways, not only to obtain the structure, but also to get functional insight into the LPMOs and their products.  Besides the LPMO we also continued to work with alginate epimerases and became interested in the chemo-enzymatic functionalization of alginate and other carbohydrates as well as the characterization thereof <cite>tondervik2013,rieder2013,arlov2014,dalheim2016,omtvedt2019,mo12020,mo22020,westereng2020</cite>. The versatility of NMR is also shown in our work following enzymatic or chemical transformation in the NMR tube <cite>khong2012,leth2018</cite>.
+I was recruited as senior scientist on structure elucidation of proteins and carbohydrates by NMR in NOBIPOL (The Norwegian Biopolymer Laboratory) at NTNU (2007-2016). During this period, we started a collaboration with [[User:Vincent Eijsink|Vincent Eijsink]] with focus on structure and functional determination of lytic polysaccharide monooxygenases (LPMO) with NMR <cite>aachmann2012,westereng2013,isaksen2014,courtade2016,courtade2018,courtade2020</cite>. Here we used NMR in many ways, not only to obtain the structure, but also to get functional insight into the LPMOs and their products.  Besides the LPMO we also continued to work with alginate epimerases and became interested in the chemo-enzymatic functionalization of alginate and other carbohydrates as well as the characterization thereof <cite>tondervik2013,rieder2013,arlov2014,dalheim2016,omtvedt2019,mo12020,mo22020,westereng2020</cite>. The versatility of NMR is also shown in our work following enzymatic or chemical transformation in the NMR tube <cite>khong2012,leth2018</cite>.
 Today, I’m leading [https://folk.ntnu.no/aachmann/ Biopolymer NMR group] at NTNU and we focus on structure and functional characterization on polysaccharides, carbohydrate modifying enzymes, multidomain proteins and biomaterials.

@@ Line 3: / Line 3: @@
 I defined my MSc project based on the knowledge gap for the interaction between cyclodextrin and proteins and setup my supervisor team Kim L. Larsen, Daniel E. Ozten and Reinhard Wimmer. Here I chose NMR spectroscopy as the main method to study the inclusion complex formation between cyclodextrin and proteins due to its ability to give atomic level information. I obtained MSc in Biotechnology at Aalborg University (Denmark) in 2001 <cite>wimmer2002,ozten2002,aachmann2003</cite>.
-The main focus of my PhD project was acquiring a deeper insight into structure elucidation with NMR and I started to work on alginate C-5 epimerases 2002-2005 in a collaboration between Svein Valla at NTNU (Norwegian University of Science and Technology) and Reinhard Wimmer at Aalborg University <cite>aachmann2006,rozeboom2008</cite>. Besides using NMR, I also focus on functional characterization of the alginate epimerases (using ITC, CD, FS and protein engineering) to understand ionic and substrate/product interaction, mode of action and role of the subunits in the alginate epimerases.
+The main focus of my PhD project was acquiring a deeper insight into structure elucidation with NMR and I started to work on alginate C-5 epimerases 2002-2005 in a collaboration between Svein Valla at NTNU (Norwegian University of Science and Technology) and Reinhard Wimmer at Aalborg University <cite>aachmann2006,rozeboom2008,gawin2020</cite>. Besides using NMR, I also focus on functional characterization of the alginate epimerases (using ITC, CD, FS and protein engineering) to understand ionic and substrate/product interaction, mode of action and role of the subunits in the alginate epimerases.
 During my Post Doc at NTNU (2005-2007) I continued with structure elucidation and functional characterization on selenocysteine containing proteins using NMR spectroscopy under the supervision of Alex Dykyy at NTNU. Here I also had a key role in building up the NMR structure determination facilities at the NV-faculty NMR center NTNU and today I lead the NMR laboratory.
-I was recruited as senior scientist on structure elucidation of proteins and carbohydrates by NMR in NOBIPOL (The Norwegian Biopolymer Laboratory) at NTNU (2007-2016). During this period, we started a collaboration with ^^^Vincent Eijsink^^^ with focus on structure and functional determination of lytic polysaccharide monooxygenases (LPMO) with NMR <cite>aachmann2012,westereng2013,isaksen2014,courtade2016,courtade2018,courtade2020</cite>. Here we used NMR in many ways, not only to obtain the structure, but also to get functional insight into the LPMOs and their products.  Besides the LPMO we also continued to work with alginate epimerases and became interested in the chemo-enzymatic functionalization of alginate and other carbohydrates as well as the characterization thereof <cite>tondervik2013,rieder2013,arlov2014,dalheim2016,omtvedt2019,mo12020,mo22020</cite>. The versatility of NMR is also shown in our work following enzymatic or chemical transformation in the NMR tube <cite>khong2012,leth2018</cite>.
+I was recruited as senior scientist on structure elucidation of proteins and carbohydrates by NMR in NOBIPOL (The Norwegian Biopolymer Laboratory) at NTNU (2007-2016). During this period, we started a collaboration with ^^^Vincent Eijsink^^^ with focus on structure and functional determination of lytic polysaccharide monooxygenases (LPMO) with NMR <cite>aachmann2012,westereng2013,isaksen2014,courtade2016,courtade2018,courtade2020</cite>. Here we used NMR in many ways, not only to obtain the structure, but also to get functional insight into the LPMOs and their products.  Besides the LPMO we also continued to work with alginate epimerases and became interested in the chemo-enzymatic functionalization of alginate and other carbohydrates as well as the characterization thereof <cite>tondervik2013,rieder2013,arlov2014,dalheim2016,omtvedt2019,mo12020,mo22020,westereng2020</cite>. The versatility of NMR is also shown in our work following enzymatic or chemical transformation in the NMR tube <cite>khong2012,leth2018</cite>.
 Today, I’m leading [https://folk.ntnu.no/aachmann/ Biopolymer NMR group] at NTNU and we focus on structure and functional characterization on polysaccharides, carbohydrate modifying enzymes, multidomain proteins and biomaterials.
@@ Line 21: / Line 21: @@
 #rozeboom2008 pmid=18574239
 #aachmann2012 pmid=23112164
 #westereng2013 pmid=23246088
 #isaksen2014 pmid=24324265
@@ Line 33: / Line 34: @@
 #mo12020 pmid=31952580
 #mo22020 pmid=32539358
 #khong2012 pmid=22424830
 #leth2018 pmid=29610517

@@ Line 7: / Line 7: @@
 During my Post Doc at NTNU (2005-2007) I continued with structure elucidation and functional characterization on selenocysteine containing proteins using NMR spectroscopy under the supervision of Alex Dykyy at NTNU. Here I also had a key role in building up the NMR structure determination facilities at the NV-faculty NMR center NTNU and today I lead the NMR laboratory.
-I was recruited as senior scientist on structure elucidation of proteins and carbohydrates by NMR in NOBIPOL (The Norwegian Biopolymer Laboratory) at NTNU (2007-2016). During this period, we started a collaboration with ^^^Vincent Eijsink^^^ with focus on structure and functional determination of lytic polysaccharide monooxygenases (LPMO) with NMR <cite>aachmann2012,westereng2013,isaksen2014,courtade2016,courtade2018,courtade2020</cite>. Here we used NMR in many ways, not only to obtain the structure, but also to get functional insight into the LPMOs and their products.  Besides the LPMO we also continued to work with alginate epimerases and became interested in the chemo-enzymatic functionalization of alginate and other carbohydrates as well as the characterization thereof [11-16]. The versatility of NMR is also shown in our work following enzymatic or chemical transformation in the NMR tube [17-18].
+I was recruited as senior scientist on structure elucidation of proteins and carbohydrates by NMR in NOBIPOL (The Norwegian Biopolymer Laboratory) at NTNU (2007-2016). During this period, we started a collaboration with ^^^Vincent Eijsink^^^ with focus on structure and functional determination of lytic polysaccharide monooxygenases (LPMO) with NMR <cite>aachmann2012,westereng2013,isaksen2014,courtade2016,courtade2018,courtade2020</cite>. Here we used NMR in many ways, not only to obtain the structure, but also to get functional insight into the LPMOs and their products.  Besides the LPMO we also continued to work with alginate epimerases and became interested in the chemo-enzymatic functionalization of alginate and other carbohydrates as well as the characterization thereof <cite>tondervik2013,rieder2013,arlov2014,dalheim2016,omtvedt2019,mo12020,mo22020</cite>. The versatility of NMR is also shown in our work following enzymatic or chemical transformation in the NMR tube <cite>khong2012,leth2018</cite>.
 Today, I’m leading [https://folk.ntnu.no/aachmann/ Biopolymer NMR group] at NTNU and we focus on structure and functional characterization on polysaccharides, carbohydrate modifying enzymes, multidomain proteins and biomaterials.
@@ Line 33: / Line 33: @@
 #mo12020 pmid=31952580
 #mo22020 pmid=32539358
 </biblio>
 <!-- Do not remove this Category tag -->
 [[Category:Contributors|Aachmann,Finn]]

@@ Line 7: / Line 7: @@
 During my Post Doc at NTNU (2005-2007) I continued with structure elucidation and functional characterization on selenocysteine containing proteins using NMR spectroscopy under the supervision of Alex Dykyy at NTNU. Here I also had a key role in building up the NMR structure determination facilities at the NV-faculty NMR center NTNU and today I lead the NMR laboratory.
-I was recruited as senior scientist on structure elucidation of proteins and carbohydrates by NMR in NOBIPOL (The Norwegian Biopolymer Laboratory) at NTNU (2007-2016). During this period, we started a collaboration with ^^^Vincent Eijsink^^^ with focus on structure and functional determination of lytic polysaccharide monooxygenases (LPMO) with NMR. Here we used NMR in many ways, not only to obtain the structure, but also to get functional insight into the LPMOs and their products[5-10].  Besides the LPMO we also continued to work with alginate epimerases and became interested in the chemo-enzymatic functionalization of alginate and other carbohydrates as well as the characterization thereof [11-16]. The versatility of NMR is also shown in our work following enzymatic or chemical transformation in the NMR tube [17-18].
+I was recruited as senior scientist on structure elucidation of proteins and carbohydrates by NMR in NOBIPOL (The Norwegian Biopolymer Laboratory) at NTNU (2007-2016). During this period, we started a collaboration with ^^^Vincent Eijsink^^^ with focus on structure and functional determination of lytic polysaccharide monooxygenases (LPMO) with NMR <cite>aachmann2012,westereng2013,isaksen2014,courtade2016,courtade2018,courtade2020</cite>. Here we used NMR in many ways, not only to obtain the structure, but also to get functional insight into the LPMOs and their products.  Besides the LPMO we also continued to work with alginate epimerases and became interested in the chemo-enzymatic functionalization of alginate and other carbohydrates as well as the characterization thereof [11-16]. The versatility of NMR is also shown in our work following enzymatic or chemical transformation in the NMR tube [17-18].
 Today, I’m leading [https://folk.ntnu.no/aachmann/ Biopolymer NMR group] at NTNU and we focus on structure and functional characterization on polysaccharides, carbohydrate modifying enzymes, multidomain proteins and biomaterials.

@@ Line 22: / Line 22: @@
 #aachmann2012 pmid=23112164
 #westereng2013 pmid=23246088
-#Isaksen2014 pmid=24324265
+#isaksen2014 pmid=24324265
+#courtade2016 pmid=27152023
-#Courtade2016 pmid=27152023
+#courtade2018 pmid=29967065
-#Courtade2018 pmid=29967065
+#courtade2020 pmid=32723819
 #tondervik2013 pmid=23808543
+#rieder2013 pmid=23399260
+#arlov2014 pmid=24844124
 </biblio>
 <!-- Do not remove this Category tag -->
 [[Category:Contributors|Aachmann,Finn]]

@@ Line 16: / Line 16: @@
 #wimmer2002 pmid=11996838
-ozten2002 pmid=12070330
+#ozten2002 pmid=12070330
 #aachmann2003 pmid=14983070
 #aachmann2006 pmid=16407237
@@ Line 28: / Line 28: @@
 #Courtade2020 pmid=32723819
 #tondervik2013 pmid=23808543
+#

@@ Line 12: / Line 12: @@
 ----
 <biblio>
 #wimmer2002 pmid=11996838
 #otzen2002 pmid=12070330

@@ Line 1: / Line 1: @@
 [[Image:Finn Aachmann profil pic.jpg|200px|right]]
-I defined my MSc project based on the knowledge gap for the interaction between cyclodextrin and proteins and setup my supervisor team Kim L. Larsen, Daniel E. Ozten and Reinhard Wimmer. Here I chose NMR spectroscopy as the main method to study the inclusion complex formation between cyclodextrin and proteins due to its ability to give atomic level information. I obtained MSc in Biotechnology at Aalborg University (Denmark) in 2001 <cite>wimmer2003,ozten2002,aachmann2003</cite>.
+I defined my MSc project based on the knowledge gap for the interaction between cyclodextrin and proteins and setup my supervisor team Kim L. Larsen, Daniel E. Ozten and Reinhard Wimmer. Here I chose NMR spectroscopy as the main method to study the inclusion complex formation between cyclodextrin and proteins due to its ability to give atomic level information. I obtained MSc in Biotechnology at Aalborg University (Denmark) in 2001 <cite>ozten2002,wimmer2003,aachmann2003</cite>.
 The main focus of my PhD project was acquiring a deeper insight into structure elucidation with NMR and I started to work on alginate C-5 epimerases 2002-2005 in a collaboration between Svein Valla at NTNU (Norwegian University of Science and Technology) and Reinhard Wimmer at Aalborg University <cite>aachmann2006,rozeboom2008</cite>. Besides using NMR, I also focus on functional characterization of the alginate epimerases (using ITC, CD, FS and protein engineering) to understand ionic and substrate/product interaction, mode of action and role of the subunits in the alginate epimerases.