User:Magali Remaud-Simeon - Revision history

Harry Brumer: fixed missing Contributor tag

2013-10-15T16:03:33Z

fixed missing Contributor tag

Harry Brumer at 10:31, 23 August 2012

2012-08-23T10:31:23Z

Magali Remaud-Simeon at 09:09, 23 August 2012

2012-08-23T09:09:53Z

Magali Remaud-Simeon at 09:07, 23 August 2012

2012-08-23T09:07:52Z

Magali Remaud-Simeon at 08:59, 23 August 2012

2012-08-23T08:59:40Z

Magali Remaud-Simeon at 13:11, 21 August 2012

2012-08-21T13:11:00Z

Magali Remaud-Simeon: Created page with " 800x600 Normal 0 21 false false false FR X-NONE X-NONE MicrosoftInternetExplorer4 Magali Remaud-Siméon graduated fro..."

2012-08-21T12:37:30Z

Created page with " 800x600 Normal 0 21 false false false FR X-NONE X-NONE MicrosoftInternetExplorer4 Magali Remaud-Siméon graduated fro..."

New page

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Magali Remaud-Siméon graduated from the National Institute of Applied Science of Toulouse in 1985 and received her PhD in 1988. Then she was as Post-Doctotal Fellow at the University of Pensylvania where she worked with Prof D. Graves in the department of Chemical and Biomolecular Engineering. From 1990 to 2000, she was an associate professor at the Institute of Technology of the University of Toulouse in the department of Applied Biology. Since 2001, she is a professor at the National Institute of Applied Science of Toulouse. As the head of the Enzyme Molecular Engineering and Catalysis group since 2001, she focuses her research activities on enzyme engineering for white biotechnology, green chemistry, Food/Feed industries and synthetic biology. Her areas of interest cover enzyme structure/activity relationship studies, kinetic resolution, evolution combining both rational and combinatorial approaches, and applications to the synthesis of new polysaccharides, oligosaccharides, glycoonjugates, esters and enantiopure compounds. She has been working on glucansucrases from GH family 70 and 13 since 1985. With her collaborators, she has elucidated the mechanism of dextran, alternan and amylose biosynthesis by dextransucrase, alternansucrase and amylosucrase, respectively. Her work is currently focused on the search and generation of enzymes displaying new specificities and improved properties towards unnatural substrate.

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		+	[[Category:Contributors\|Remaud-Simeon, Magali]]

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+Magali Remaud-Simeon graduated from  the National Institute of Applied Science of Toulouse in 1985 and received  her PhD in 1988. Then she was as Post-Doctoral Fellow at the University of  Pensylvania, where she worked with Prof. D. Graves in the Department of  Chemical and Biomolecular Engineering. From 1990 to 2000, she was an Associate Professor at the Institute of Technology of the University of Toulouse in the Department of Applied Biology. She joined the group Biocatalysis of Prof. P. Monsan at the "Laboratoire d'Ingénierie des Systèmes et des Procédés" in 1994. Since 2001, she is a Professor  at the National Institute of Applied Science of Toulouse. At the head of the Enzyme  Molecular Engineering and Catalysis group since 2001, she focuses her research activities on enzyme engineering for white biotechnology, green chemistry, Food/Feed industries, and synthetic biology. Her areas of interest cover enzyme structure/activity relationship studies, kinetic resolution, evolution combining both rational and combinatorial approaches, and applications to the synthesis of new polysaccharides, oligosaccharides, glyco-conjugates, esters, and enantiopure compounds.  She has been working on glucansucrases from [[GH70]] and [[GH13]] since 1985. With her collaborators, she has investigated the mechanism of dextran, alternan and  amylose biosynthesis by dextransucrase, alternansucrase and amylosucrase, respectively. Her work is currently focusing on the generation of enzymes displaying new specificities and improved properties towards unnatural substrates.
-Magali Remaud-Simeon graduated from  the National Institute of Applied Science of Toulouse in 1985 and received  her PhD in 1988. Then she was as Post-Doctotal Fellow at the University of  Pensylvania where she worked with Prof D. Graves in the department of  Chemical and Biomolecular Engineering. From 1990 to 2000, she was an  associate professor at the Institute of Technology of the University of  Toulouse in the department of Applied Biology. She joined the group of Biocatalysis of Prof. P. MONSAN at the "laboratoire d'Ingénierie des systèmes et des procédés" in 1994. Since 2001, she is a professor  at the National Institute of Applied Science of Toulouse. At the head of the Enzyme  Molecular Engineering and Catalysis group since 2001, she focuses her research activities on enzyme engineering for white biotechnology, green  chemistry, Food/Feed industries and synthetic biology. Her areas of interest  cover enzyme structure/activity relationship studies, kinetic resolution,  evolution combining both rational and combinatorial approaches, and  applications to the synthesis of  new  polysaccharides, oligosaccharides, glycoonjugates, esters and enantiopure  compounds.  She has been working on glucansucrases from GH family 70 and 13 since 1985. With her collaborators, she has  investigated the mechanism of dextran, alternan and  amylose biosynthesis by dextransucrase, alternansucrase and amylosucrase,  respectively. Her work is currently focusing on the generation of  enzymes displaying new specificities and improved properties towards  unnatural substrates.
+E-mail: <email>magali.remaud@insa-toulouse.fr</email>
-E-mail: magali.remaud@insa-toulouse.fr http://www.lisbp.insa-toulouse.fr
+http://www.lisbp.insa-toulouse.fr
 <biblio>

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-Magali Remaud-Simeon graduated from  the National Institute of Applied Science of Toulouse in 1985 and received  her PhD in 1988. Then she was as Post-Doctotal Fellow at the University of  Pensylvania where she worked with Prof D. Graves in the department of  Chemical and Biomolecular Engineering. From 1990 to 2000, she was an  associate professor at the Institute of Technology of the University of  Toulouse in the department of Applied Biology. She joined the group of Biocatalysis of Prof. P. MONSAN at the "laboratoire d'Ingénierie des systèmes et des procédés" in 1994. Since 2001, she is a professor  at the National Institute of Applied Science of Toulouse. As the head of the Enzyme  Molecular Engineering and Catalysis group since 2001, she focuses her research activities on enzyme engineering for white biotechnology, green  chemistry, Food/Feed industries and synthetic biology. Her areas of interest  cover enzyme structure/activity relationship studies, kinetic resolution,  evolution combining both rational and combinatorial approaches, and  applications to the synthesis of  new  polysaccharides, oligosaccharides, glycoonjugates, esters and enantiopure  compounds.  She has been working on glucansucrases from GH family 70 and 13 since 1985. With her collaborators, she has  investigated the mechanism of dextran, alternan and  amylose biosynthesis by dextransucrase, alternansucrase and amylosucrase,  respectively. Her work is currently focused on the search and generation of  enzymes displaying new specificities and improved properties towards  unnatural substrates.
+Magali Remaud-Simeon graduated from  the National Institute of Applied Science of Toulouse in 1985 and received  her PhD in 1988. Then she was as Post-Doctotal Fellow at the University of  Pensylvania where she worked with Prof D. Graves in the department of  Chemical and Biomolecular Engineering. From 1990 to 2000, she was an  associate professor at the Institute of Technology of the University of  Toulouse in the department of Applied Biology. She joined the group of Biocatalysis of Prof. P. MONSAN at the "laboratoire d'Ingénierie des systèmes et des procédés" in 1994. Since 2001, she is a professor  at the National Institute of Applied Science of Toulouse. At the head of the Enzyme  Molecular Engineering and Catalysis group since 2001, she focuses her research activities on enzyme engineering for white biotechnology, green  chemistry, Food/Feed industries and synthetic biology. Her areas of interest  cover enzyme structure/activity relationship studies, kinetic resolution,  evolution combining both rational and combinatorial approaches, and  applications to the synthesis of  new  polysaccharides, oligosaccharides, glycoonjugates, esters and enantiopure  compounds.  She has been working on glucansucrases from GH family 70 and 13 since 1985. With her collaborators, she has  investigated the mechanism of dextran, alternan and  amylose biosynthesis by dextransucrase, alternansucrase and amylosucrase,  respectively. Her work is currently focusing on the generation of  enzymes displaying new specificities and improved properties towards  unnatural substrates.
 E-mail: magali.remaud@insa-toulouse.fr http://www.lisbp.insa-toulouse.fr

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 #moulis2006 pmid=16864576
 #brison2012 pmid=22262856
-#guerin2012 Guérin F, Barbe S., Pizzut-Serin S, Potocki-Véronèse G, Guieysse D, Guillet V, Monsan P, Mourey L, Remaud-Simeon M, André I and Tranier S.''Structural investigation of the thermostability and product specificity of amylosucrase from the bacterium Deinococcus geothermalis''. J. Biol Chem 2012; 287(9):6642-6654
+#guerin2012 pmid=22210773
-#champion2009 Champion E, André I, Moulis C, Boutet J, Descroix K, Morel S, Monsan P, Mulard LA, Remaud-Simeon M. 2009a. ''Design of alpha-transglucosidases of controlled specificity for programmed chemoenzymatic synthesis of antigenic oligosaccharides''. J Am Chem Soc 2009; 131(21):7379-89
+#champion2009 pmid=19432472
-#albenne2004 Albenne C, Skov LK, Mirza O, Gajhede M, Feller G, D’Amico S, Andre G, Potocki-Véronèse  G, Van Der Veen B, Monsan P, Remaud-Simeon M. ''Molecular basis of the amylose-like polymer formation catalysed by Neisseria polysaccharea amylosucrase''. J Biol Chem 2004; 279, 726-734
+#albenne2004 pmid=14570882
 </biblio>

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 E-mail: magali.remaud@insa-toulouse.fr http://www.lisbp.insa-toulouse.fr
-Glucansucrases from GH 70 Family
+<biblio>
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← Older revision		Revision as of 13:11, 21 August 2012
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−	Magali Remaud-~~Siméon~~ graduated from the National Institute of Applied Science of Toulouse in 1985 and received her PhD in 1988. Then she was as Post-Doctotal Fellow at the University of Pensylvania where she worked with Prof D. Graves in the department of Chemical and Biomolecular Engineering. From 1990 to 2000, she was an associate professor at the Institute of Technology of the University of Toulouse in the department of Applied Biology. Since 2001, she is a professor at the National Institute of Applied Science of Toulouse. As the head of the Enzyme Molecular Engineering and Catalysis group since 2001, she focuses her research activities on enzyme engineering for white biotechnology, green chemistry, Food/Feed industries and synthetic biology. Her areas of interest cover enzyme structure/activity relationship studies, kinetic resolution, evolution combining both rational and combinatorial approaches, and applications to the synthesis of new polysaccharides, oligosaccharides, glycoonjugates, esters and enantiopure compounds. She has been working on glucansucrases from GH family 70 and 13 since 1985. With her collaborators, she has ~~elucidated~~ the mechanism of dextran, alternan and amylose biosynthesis by dextransucrase, alternansucrase and amylosucrase, respectively. Her work is currently focused on the search and generation of enzymes displaying new specificities and improved properties towards unnatural ~~substrate~~.	+	Magali Remaud-Simeon graduated from the National Institute of Applied Science of Toulouse in 1985 and received her PhD in 1988. Then she was as Post-Doctotal Fellow at the University of Pensylvania where she worked with Prof D. Graves in the department of Chemical and Biomolecular Engineering. From 1990 to 2000, she was an associate professor at the Institute of Technology of the University of Toulouse in the department of Applied Biology. She joined the group of Biocatalysis of Prof. P. MONSAN at the "laboratoire d'Ingénierie des systèmes et des procédés" in 1994. Since 2001, she is a professor at the National Institute of Applied Science of Toulouse. As the head of the Enzyme Molecular Engineering and Catalysis group since 2001, she focuses her research activities on enzyme engineering for white biotechnology, green chemistry, Food/Feed industries and synthetic biology. Her areas of interest cover enzyme structure/activity relationship studies, kinetic resolution, evolution combining both rational and combinatorial approaches, and applications to the synthesis of new polysaccharides, oligosaccharides, glycoonjugates, esters and enantiopure compounds. She has been working on glucansucrases from GH family 70 and 13 since 1985. With her collaborators, she has investigated the mechanism of dextran, alternan and amylose biosynthesis by dextransucrase, alternansucrase and amylosucrase, respectively. Her work is currently focused on the search and generation of enzymes displaying new specificities and improved properties towards unnatural substrates.
		+
		+	E-mail: magali.remaud@insa-toulouse.fr http://www.lisbp.insa-toulouse.fr
		+
		+	Glucansucrases from GH 70 Family
		+	Normal 0 21 false false false FR X-NONE X-NONE
		+
		+	André I, Potocki-Véronèse G, Morel S, Monsan P, Remaud-Siméon M. 2010. Sucrose-acting transglucosidases for biocatalysis. Top. Curr. Chem. carbohydrates in sustainable development II. Eds Rauter AP, Vogel P, Queneau Y. Vol. 294, pp 25-48 PMID:21626747
		+
		+	Normal 0 21 false false false FR X-NONE X-NONE
		+
		+	Fabre E, Bozonnet S, Arcache A, Willemot RM, Vignon M, Monsan P, Remaud-Simeon, M. Role of the two catalytic domains of DSR-E dextransucrase and their involvement in the formation of highly alpha-1,2 branched dextran. J Bacteriol 2005 Jan; 187(1) 296-303. doi: 10.1128/JB.187.1.296-303.2005 PMID:15601714
		+
		+	Normal 0 21 false false false FR X-NONE X-NONE
		+
		+	Moulis C, Joucla G, Harrison D, Fabre E, Potocki-Veronese G, Monsan P, Remaud-Simeon M. Understanding the polymerization mechanism of glycoside-hydrolase family 70 glucansucrases. J Biol. Chem 2006 Oct 20; 281 (42) 31254-31267. DOI: 10.1074/jbc.M604850200 PMID:16864576
		+
		+	Brison Y, Pijning T, Malbert Y, Fabre E, Morel S, Potocki-Veronese G, Monsan P, Tranier S, Remaud-Simeon M, Dijkstra BW. Functional and Structural Characterization of alpha-(1 -> 2) Branching Sucrase Derived from DSR-E Glucansucrase. J Biol Chem 2012 March 9; 287(11) 7915-7924. doi: 10.1074/jbc.M111.305078 PMID:22262856
		+
		+	Glucansucrases from GH13 Family
		+	Normal 0 21 false false false FR X-NONE X-NONE
		+
		+	Guérin F, Barbe S., Pizzut-Serin S, Potocki-Véronèse G, Guieysse D, Guillet V, Monsan P, Mourey L, Remaud-Simeon M, André I and Tranier S.. Structural investigation of the thermostability and product specificity of amylosucrase from the bacterium Deinococcus geothermalis. J. Biol Chem 2012; 287(9):6642-6654
		+
		+	Champion E, André I, Moulis C, Boutet J, Descroix K, Morel S, Monsan P, Mulard LA, Remaud-Simeon M. 2009a. Design of alpha-transglucosidases of controlled specificity for programmed chemoenzymatic synthesis of antigenic oligosaccharides. J Am Chem Soc 2009; 131(21):7379-89
		+
		+	Albenne C, Skov LK, Mirza O, Gajhede M, Feller G, D’Amico S, Andre G, Potocki-Véronèse G, Van Der Veen B, Monsan P, Remaud-Simeon M. Molecular basis of the amylose-like polymer formation catalysed by Neisseria polysaccharea amylosucrase. J Biol Chem 2004; 279, 726-734.
		+	Normal 0 21 false false false FR X-NONE X-NONE