Carbohydrate Binding Module Families

This page lists all the Carbohydrate Binding Module (CBM) Family pages in CAZypedia that have been given Curator Approved status, as well as those that are currently under construction.

Note (May 2013): We are just beginning to develop individual CBM pages in CAZypedia, although a long-term goal is to have complete coverage of all of the CBM families represented in the CAZy database. This effort is being led by ^^^Alicia Lammerts van Bueren^^^, together with theSenior Curators. If you would like to become involved in the development of the CBM pages, please contact ^^^Alicia Lammerts van Bueren^^^ directly, or usingthis form.

Overview

Carbohydrate-binding modules (CBMs) are non-catalytic proteins with the capacity to bind to soluble and crystalline carbohydrates. CBMs are typically found within a longer protein sequence, with catalytic modules of carbohydrate active enzymes, , e.g. Glycoside Hydrolases and Polysaccharide Lyases, and serve to enhance the catalytic activity of the enzymatic module(s) [1, 2, 3, 4, 5, 6].

Curator Approved

These pages have been approved by the Responsible Curator as essentially complete. CAZypedia is a living document, so further improvement of these pages is still possible; please see the individual pages for more information.

There are currently 55 Curator approved Carbohydrate Binding Module (CBM) Family pages in CAZypedia.

• CBM1
• CBM2
• CBM3
• CBM4
• CBM5
• CBM6
• CBM7
• CBM9
• CBM10
• CBM14
• CBM15
• CBM16
• CBM19
• CBM20
• CBM21
• CBM22
• CBM28
• CBM29
• CBM32
• CBM33
• CBM35
• CBM41
• CBM42
• CBM44
• CBM46
• CBM48
• CBM49
• CBM50
• CBM55
• CBM58
• CBM60
• CBM62
• CBM63
• CBM65
• CBM66
• CBM67
• CBM71
• CBM73
• CBM75
• CBM76
• CBM77
• CBM78
• CBM79
• CBM80
• CBM81
• CBM82
• CBM83
• CBM86
• CBM87
• CBM89
• CBM92
• CBM94
• CBM99
• CBM100
• CBM101

Under construction

These pages are currently under construction in CAZypedia. As such, the Responsible Curator has deemed that the page's content is not quite up to CAZypedia's standards for full public consumption. All information on these pages should therefore be considered to be under revision and may be subject to major changes.

There are currently 6 Carbohydrate Binding Module Family pages Under construction in CAZypedia.

• CBM11
• CBM18
• CBM61
• CBM74
• CBM85
• CBM91

Unassigned pages

The following Unassigned pages are currently lacking a Responsible Curator and one or more Authors. If you are an expert on any of these families and would like to help us improve CAZypedia by getting involved with the production and maintenance of the corresponding page(s), please contact a member of the Board of Curators directly, or via this form.

All CBM Family pages not listed above are currently unassigned. Please contact us if you'd like to get involved with the creation of these pages.

Deleted families

The following families have been deleted from the CAZy database. Please see the individual CAZypedia pages and links to the corresponding CAZy DB pages for specific explanations.

There are currently 2 pages in CAZypedia that describe Carbohydrate Binding Module families deleted from the CAZy DB.

• CBM7
• CBM33

References

1. Boraston AB, Bolam DN, Gilbert HJ, and Davies GJ. (2004). Carbohydrate-binding modules: fine-tuning polysaccharide recognition. Biochem J. 2004;382(Pt 3):769-81. DOI:10.1042/BJ20040892 |
2. Shoseyov O, Shani Z, and Levy I. (2006). Carbohydrate binding modules: biochemical properties and novel applications. Microbiol Mol Biol Rev. 2006;70(2):283-95. DOI:10.1128/MMBR.00028-05 |
3. Hashimoto H (2006). Recent structural studies of carbohydrate-binding modules. Cell Mol Life Sci. 2006;63(24):2954-67. DOI:10.1007/s00018-006-6195-3 |
4. Guillén D, Sánchez S, and Rodríguez-Sanoja R. (2010). Carbohydrate-binding domains: multiplicity of biological roles. Appl Microbiol Biotechnol. 2010;85(5):1241-9. DOI:10.1007/s00253-009-2331-y |
5. Ficko-Blean E and Boraston AB. (2012). Insights into the recognition of the human glycome by microbial carbohydrate-binding modules. Curr Opin Struct Biol. 2012;22(5):570-7. DOI:10.1016/j.sbi.2012.07.009 |
6. Gilbert HJ, Knox JP, and Boraston AB. (2013). Advances in understanding the molecular basis of plant cell wall polysaccharide recognition by carbohydrate-binding modules. Curr Opin Struct Biol. 2013;23(5):669-77. DOI:10.1016/j.sbi.2013.05.005 |
7. Cantarel BL, Coutinho PM, Rancurel C, Bernard T, Lombard V, and Henrissat B. (2009). The Carbohydrate-Active EnZymes database (CAZy): an expert resource for Glycogenomics. Nucleic Acids Res. 2009;37(Database issue):D233-8. DOI:10.1093/nar/gkn663 |

8. Davies, G.J. and Sinnott, M.L. (2008) Sorting the diverse: the sequence-based classifications of carbohydrate-active enzymes. Biochem. J. (A BJ Classics review, online only). DOI: 10.1042/BJ20080382

9. Lombard V, Golaconda Ramulu H, Drula E, Coutinho PM, and Henrissat B. (2014). The carbohydrate-active enzymes database (CAZy) in 2013. Nucleic Acids Res. 2014;42(Database issue):D490-5. DOI:10.1093/nar/gkt1178 |