CAZypedia needs your help! We have many unassigned GH, PL, CE, AA, GT, and CBM pages in need of Authors and Responsible Curators.
Scientists at all career stages, including students, are welcome to contribute to CAZypedia. Read more here, and in the 10th anniversary article in Glycobiology.
New to the CAZy classification? Read this first.
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Consider attending the 15th Carbohydrate Bioengineering Meeting in Ghent, 5-8 May 2024.
Difference between revisions of "Glycoside Hydrolase Family 139"
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== Substrate specificities == | == Substrate specificities == | ||
| + | Glycoside hydrolases of GH139 family ([www.cazy.org/GH139.html CAZy]) display the novel a-2-O-methyl-L-fucosidase activity (EC…….). The enzyme BT0984 from Bacteroides thetaiotaomicron is the only member of this family that has been characterized. This exo-enzyme targets the a-2-O-methyl-L-fucose at chain B of the complex rhamnogalacturonan-II present in the plants cell wall. All of genes encoding family 139 members are found in bacteria. | ||
| + | |||
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Revision as of 13:27, 11 February 2018
This page is currently under construction. This means that the Responsible Curator has deemed that the page's content is not quite up to CAZypedia's standards for full public consumption. All information should be considered to be under revision and may be subject to major changes.
- Author: ^^^Ana Luis^^^
- Responsible Curator: ^^^Harry Gilbert^^^
| Glycoside Hydrolase Family GH139 | |
| Clan | none |
| Mechanism | unknown |
| Active site residues | not known |
| CAZy DB link | |
| http://www.cazy.org/GH139.html | |
Substrate specificities
Glycoside hydrolases of GH139 family ([www.cazy.org/GH139.html CAZy]) display the novel a-2-O-methyl-L-fucosidase activity (EC…….). The enzyme BT0984 from Bacteroides thetaiotaomicron is the only member of this family that has been characterized. This exo-enzyme targets the a-2-O-methyl-L-fucose at chain B of the complex rhamnogalacturonan-II present in the plants cell wall. All of genes encoding family 139 members are found in bacteria.
Content is to be added here.
Authors may get an idea of what to put in each field from Curator Approved Glycoside Hydrolase Families. (TIP: Right click with your mouse and open this link in a new browser window...)
In the meantime, please see these references for an essential introduction to the CAZy classification system: [1, 2].
Kinetics and Mechanism
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Catalytic Residues
Content is to be added here.
Three-dimensional structures
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Family Firsts
- First stereochemistry determination
- Content is to be added here.
- First catalytic nucleophile identification
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- First general acid/base residue identification
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- First 3-D structure
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References
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Davies, G.J. and Sinnott, M.L. (2008) Sorting the diverse: the sequence-based classifications of carbohydrate-active enzymes. The Biochemist, vol. 30, no. 4., pp. 26-32. Download PDF version.
- Cantarel BL, Coutinho PM, Rancurel C, Bernard T, Lombard V, and Henrissat B. (2009). The Carbohydrate-Active EnZymes database (CAZy): an expert resource for Glycogenomics. Nucleic Acids Res. 2009;37(Database issue):D233-8. DOI:10.1093/nar/gkn663 |