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Difference between revisions of "User:Joel Weadge"

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[https://www.wlu.ca/academics/faculties/faculty-of-science/faculty-profiles/joel-weadge/index.html Joel Weadge] is an Associate Professor in the [https://students.wlu.ca/programs/science/biology/index.html Biology Department] at [https://www.wlu.ca Wilfrid Laurier University]  Dr. Weadge graduated with his B.Sc. from the [https://www.uoguelph.ca University of Guelph] and then went on to do his Ph.D. in [https://www.uoguelph.ca/mcb/ Molecular and Cell Biology] at the same institution under [https://www.uoguelph.ca/mcb/people/dr-anthony-clarke Dr. Anthony Clarke]  while studying peptidoglycan acetylesterases. Dr. Weadge then undertook a research fellowship appointment with Dr. Monica Palcic in the enzymology research group at [https://www.carlsbergfondet.dk/en/About-the-Foundation/The-Carlsberg-Foundation/The-Carlsberg-family/The-Carlsberg-Laboratory- Carlsberg Laboratory] in Copenhagen, Denmark, where he worked on structure-function relationships of glycosyltransferases responsible for blood group determination. He then joined [https://lab.research.sickkids.ca/howell/ Dr. Lynne Howell’s lab] as a postdoctoral fellow at the [http://www.sickkids.ca/index.html Hospital for Sick Children in Toronto] with CIHR and NSERC fellowships. While at Sick Kids, he continued to work on glycosyltransferases, carbohydrate esterase and acetyltransferases inherent in the alginate biosynthetic complex. Dr. Weadge’s diverse research experiences in the structure-function characterization of glycolic-enzymes and protein export apparati from a variety of carbohydrate systems (peptidoglycan, alginate, blood group antigens) form the basis for his group’s current research interests on cellulose, an exopolysaccharide found in bacterial biofilms.
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[https://www.wlu.ca/academics/faculties/faculty-of-science/faculty-profiles/joel-weadge/index.html Joel Weadge] is an Associate Professor in the [https://students.wlu.ca/programs/science/biology/index.html Biology Department] at [https://www.wlu.ca Wilfrid Laurier University]  Dr. Weadge graduated with his B.Sc. from the [https://www.uoguelph.ca University of Guelph] and then went on to do his Ph.D. in [https://www.uoguelph.ca/mcb/ Molecular and Cell Biology] at the same institution under [https://www.uoguelph.ca/mcb/people/dr-anthony-clarke Dr. Anthony Clarke]  while studying peptidoglycan acetylesterases. Dr. Weadge then undertook a research fellowship appointment with Dr. Monica Palcic in the enzymology research group at [https://www.carlsbergfondet.dk/en/About-the-Foundation/The-Carlsberg-Foundation/The-Carlsberg-family/The-Carlsberg-Laboratory- Carlsberg Laboratory] in Copenhagen, Denmark, where he worked on structure-function relationships of glycosyltransferases, including those responsible for blood group determination. He then joined [https://lab.research.sickkids.ca/howell/ Dr. Lynne Howell’s lab] as a postdoctoral fellow at the [http://www.sickkids.ca/index.html Hospital for Sick Children in Toronto] with CIHR and NSERC fellowships. While at Sick Kids, he continued to work on glycosyltransferases, carbohydrate esterase and acetyltransferases inherent in the alginate biosynthetic complex. Dr. Weadge’s diverse research experiences in the structure-function characterization of glycolic-enzymes and protein export apparati from a variety of carbohydrate systems (peptidoglycan, alginate, blood group antigens) form the basis for his group’s current research interests on cellulose, an exopolysaccharide found in bacterial biofilms.
  
  
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#Weadge2005 pmid=16111493
 
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#Weadge2006 pmid=16411760
 
#Weadge2006 pmid=16411760
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#Pfeffer2006 pmid=16428393
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#Weadge2007 pmid=17388571
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#Li2009 pmid=19284783
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#Adlercreutz2010 pmid=20206917
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#Weadge2005 pmid=16111493
 
#Weadge2005 pmid=16111493
 
#Weadge2005 pmid=16111493
 
#Weadge2005 pmid=16111493

Revision as of 09:02, 19 July 2019

Weadge Headshot.jpg


Joel Weadge is an Associate Professor in the Biology Department at Wilfrid Laurier University Dr. Weadge graduated with his B.Sc. from the University of Guelph and then went on to do his Ph.D. in Molecular and Cell Biology at the same institution under Dr. Anthony Clarke while studying peptidoglycan acetylesterases. Dr. Weadge then undertook a research fellowship appointment with Dr. Monica Palcic in the enzymology research group at Carlsberg Laboratory in Copenhagen, Denmark, where he worked on structure-function relationships of glycosyltransferases, including those responsible for blood group determination. He then joined Dr. Lynne Howell’s lab as a postdoctoral fellow at the Hospital for Sick Children in Toronto with CIHR and NSERC fellowships. While at Sick Kids, he continued to work on glycosyltransferases, carbohydrate esterase and acetyltransferases inherent in the alginate biosynthetic complex. Dr. Weadge’s diverse research experiences in the structure-function characterization of glycolic-enzymes and protein export apparati from a variety of carbohydrate systems (peptidoglycan, alginate, blood group antigens) form the basis for his group’s current research interests on cellulose, an exopolysaccharide found in bacterial biofilms.



  1. Weadge JT, Pfeffer JM, and Clarke AJ. (2005) Identification of a new family of enzymes with potential O-acetylpeptidoglycan esterase activity in both Gram-positive and Gram-negative bacteria. BMC Microbiol. 5, 49. DOI:10.1186/1471-2180-5-49 | PubMed ID:16111493 | HubMed [Weadge2005]
  2. Weadge JT, Pfeffer JM, and Clarke AJ. (2005) Identification of a new family of enzymes with potential O-acetylpeptidoglycan esterase activity in both Gram-positive and Gram-negative bacteria. BMC Microbiol. 5, 49. DOI:10.1186/1471-2180-5-49 | PubMed ID:16111493 | HubMed [Weadge2005]
  3. Weadge JT, Pfeffer JM, and Clarke AJ. (2005) Identification of a new family of enzymes with potential O-acetylpeptidoglycan esterase activity in both Gram-positive and Gram-negative bacteria. BMC Microbiol. 5, 49. DOI:10.1186/1471-2180-5-49 | PubMed ID:16111493 | HubMed [Weadge2005]
  4. Weadge JT, Pfeffer JM, and Clarke AJ. (2005) Identification of a new family of enzymes with potential O-acetylpeptidoglycan esterase activity in both Gram-positive and Gram-negative bacteria. BMC Microbiol. 5, 49. DOI:10.1186/1471-2180-5-49 | PubMed ID:16111493 | HubMed [Weadge2005]
  5. Weadge JT and Clarke AJ. (2006) Identification and characterization of O-acetylpeptidoglycan esterase: a novel enzyme discovered in Neisseria gonorrhoeae. Biochemistry. 45, 839-51. DOI:10.1021/bi051679s | PubMed ID:16411760 | HubMed [Weadge2006]
  6. Pfeffer JM, Strating H, Weadge JT, and Clarke AJ. (2006) Peptidoglycan O acetylation and autolysin profile of Enterococcus faecalis in the viable but nonculturable state. J Bacteriol. 188, 902-8. DOI:10.1128/JB.188.3.902-908.2006 | PubMed ID:16428393 | HubMed [Pfeffer2006]
  7. Weadge JT and Clarke AJ. (2007) Neisseria gonorrheae O-acetylpeptidoglycan esterase, a serine esterase with a Ser-His-Asp catalytic triad. Biochemistry. 46, 4932-41. DOI:10.1021/bi700254m | PubMed ID:17388571 | HubMed [Weadge2007]
  8. Li Y, Thapa P, Hawke D, Kondo Y, Furukawa K, Furukawa K, Hsu FF, Adlercreutz D, Weadge J, Palcic MM, Wang PG, Levery SB, and Zhou D. (2009) Immunologic glycosphingolipidomics and NKT cell development in mouse thymus. J Proteome Res. 8, 2740-51. DOI:10.1021/pr801040h | PubMed ID:19284783 | HubMed [Li2009]
  9. Adlercreutz D, Weadge JT, Petersen BO, Duus JØ, Dovichi NJ, and Palcic MM. (2010) Enzymatic synthesis of Gb3 and iGb3 ceramides. Carbohydr Res. 345, 1384-8. DOI:10.1016/j.carres.2010.02.006 | PubMed ID:20206917 | HubMed [Adlercreutz2010]
All Medline abstracts: PubMed | HubMed