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Difference between revisions of "User:Wade Abbott"
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Dr. Abbott received his PhD from the [http://www.uvic.ca/ University of Victoria] in 2005. He then studied the molecular basis of protein-carbohydrate interactions under Dr. ^^^Alisdair Boraston^^^ at the [http://www.uvic.ca/ University of Victoria]. In 2008, Dr. Abbott joined Dr. ^^^Harry Gilbert^^^ at the [http://www.ccrc.uga.edu/ Complex Carbohydrate Research Centre], at the [http://uga.edu/ University of Georgia] where he investigated the functional genomics of carbohydrate utilization pathways from intestinal bacteria. Currently, Dr. Abbott is a Research Scientist for [http://www.agr.gc.ca/index_e.php/ Agriculture and Agri-Food Canada] based at the [http://www.agr.gc.ca/eng/science-and-innovation/research-centres/alberta/lethbridge-research-centre/?id=1180547946064/ Lethbridge Research Centre] and Adjunct Professor at the [http://www.uleth.ca/ University of Lethbridge]. His research program investigates the mechanisms of complex carbohydrate modification by intestinal bacteria, and is developing applications for carbohydrates in animal agriculture and human intestinal health. | Dr. Abbott received his PhD from the [http://www.uvic.ca/ University of Victoria] in 2005. He then studied the molecular basis of protein-carbohydrate interactions under Dr. ^^^Alisdair Boraston^^^ at the [http://www.uvic.ca/ University of Victoria]. In 2008, Dr. Abbott joined Dr. ^^^Harry Gilbert^^^ at the [http://www.ccrc.uga.edu/ Complex Carbohydrate Research Centre], at the [http://uga.edu/ University of Georgia] where he investigated the functional genomics of carbohydrate utilization pathways from intestinal bacteria. Currently, Dr. Abbott is a Research Scientist for [http://www.agr.gc.ca/index_e.php/ Agriculture and Agri-Food Canada] based at the [http://www.agr.gc.ca/eng/science-and-innovation/research-centres/alberta/lethbridge-research-centre/?id=1180547946064/ Lethbridge Research Centre] and Adjunct Professor at the [http://www.uleth.ca/ University of Lethbridge]. His research program investigates the mechanisms of complex carbohydrate modification by intestinal bacteria, and is developing applications for carbohydrates in animal agriculture and human intestinal health. | ||
| − | + | I have contributed to structure-function studies of the following CAZymes: | |
'''Glycoside Hydrolases''' | '''Glycoside Hydrolases''' | ||
*[[GH20]] ''Streptococcus pneumoniae'' exo-β-D-N-acetylglucosaminidase (SpnGH20/StrH)<cite>Pluvinage2013</cite>. ''Streptococcus pneumoniae'' exo-β-D-N-acetylglucosaminidase (SpnGH20/StrH). <cite>Pluvinage2011</cite> | *[[GH20]] ''Streptococcus pneumoniae'' exo-β-D-N-acetylglucosaminidase (SpnGH20/StrH)<cite>Pluvinage2013</cite>. ''Streptococcus pneumoniae'' exo-β-D-N-acetylglucosaminidase (SpnGH20/StrH). <cite>Pluvinage2011</cite> | ||
| − | *[[GH28]] ''Yersinia enterocolitica'' Exopolygalacturonase (YeGH28)<cite>Abbott2007a</cite> | + | *[[GH28]] ''Yersinia enterocolitica'' Exopolygalacturonase (YeGH28)<cite>Abbott2007a</cite>. Family First |
*[[GH85]] ''Streptococcus pneumoniae'' Endo-beta-D-glucosaminidase D (SpGH85/EndoD)<cite>Abbott2009a</cite> | *[[GH85]] ''Streptococcus pneumoniae'' Endo-beta-D-glucosaminidase D (SpGH85/EndoD)<cite>Abbott2009a</cite> | ||
| − | |||
'''Polysaccharide Lyases''' | '''Polysaccharide Lyases''' | ||
| − | *[[PL2]] ''Yersinia enterocolitica'' Perplasmic pectate lyase (YePL2A)<cite>Abbott2007c</cite>. ''Paenibacillus sp. Y412MC10'' Cytoplasmic endolytic pectate lyase (PaePL2)<cite>Abbott2013</cite>. | + | *[[PL2]] ''Yersinia enterocolitica'' Perplasmic pectate lyase (YePL2A)<cite>Abbott2007c</cite>. ''Paenibacillus sp. Y412MC10'' Cytoplasmic endolytic pectate lyase (PaePL2)<cite>Abbott2013</cite>. Family First |
| − | *[[PL22]] ''Yersinia enterocolitica'' Cytoplasmic oligogalacturonate lyase (YePL22/Ogl)<cite>Abbott2010a</cite> | + | *[[PL22]] ''Yersinia enterocolitica'' Cytoplasmic oligogalacturonate lyase (YePL22/Ogl)<cite>Abbott2010a</cite>. Family First |
'''Carbohydrate Binding Modules''' | '''Carbohydrate Binding Modules''' | ||
| − | *[[CBM6]] | + | *[[CBM6]] <cite>Abbott2009b</cite> |
| − | *[[CBM32]] ''Yersinia enterocolitica'' Polygalacturonic acid binding protein (YeCBM32)<cite>Abbott2007b</cite>. | + | *[[CBM32]] ''Yersinia enterocolitica'' Polygalacturonic acid binding protein (YeCBM32)<cite>Abbott2007b</cite>. ''Streptococcus pneumoniae'' EndoD CBM (SpnCBM32)<cite>Abbott2011</cite>. |
| − | *[[CBM35]] | + | *[[CBM35]] <cite>Correia2010</cite> |
| − | *[[CBM51]] ''Clostridium perfringens'' Blood group binding CBMs (GH95CBM51 and GH98CBM51) | + | *[[CBM51]] ''Clostridium perfringens'' Blood group binding CBMs (GH95CBM51 and GH98CBM51)<cite>Finn2008</cite> |
'''Carbohydrate Esterases''' | '''Carbohydrate Esterases''' | ||
Revision as of 14:13, 23 September 2013
Dr. Abbott received his PhD from the University of Victoria in 2005. He then studied the molecular basis of protein-carbohydrate interactions under Dr. ^^^Alisdair Boraston^^^ at the University of Victoria. In 2008, Dr. Abbott joined Dr. ^^^Harry Gilbert^^^ at the Complex Carbohydrate Research Centre, at the University of Georgia where he investigated the functional genomics of carbohydrate utilization pathways from intestinal bacteria. Currently, Dr. Abbott is a Research Scientist for Agriculture and Agri-Food Canada based at the Lethbridge Research Centre and Adjunct Professor at the University of Lethbridge. His research program investigates the mechanisms of complex carbohydrate modification by intestinal bacteria, and is developing applications for carbohydrates in animal agriculture and human intestinal health.
I have contributed to structure-function studies of the following CAZymes: Glycoside Hydrolases
- GH20 Streptococcus pneumoniae exo-β-D-N-acetylglucosaminidase (SpnGH20/StrH)[1]. Streptococcus pneumoniae exo-β-D-N-acetylglucosaminidase (SpnGH20/StrH). [2]
Polysaccharide Lyases
- PL2 Yersinia enterocolitica Perplasmic pectate lyase (YePL2A)[5]. Paenibacillus sp. Y412MC10 Cytoplasmic endolytic pectate lyase (PaePL2)[6]. Family First
Carbohydrate Binding Modules
- CBM6 [8]
- CBM32 Yersinia enterocolitica Polygalacturonic acid binding protein (YeCBM32)[9]. Streptococcus pneumoniae EndoD CBM (SpnCBM32)[10].
- CBM35 [11]
- CBM51 Clostridium perfringens Blood group binding CBMs (GH95CBM51 and GH98CBM51)[12]
Carbohydrate Esterases
<biblio>
- Abbott2007a pmid=17397864
- Abbott2007b pmid=17292916
- Abbott2007c pmid=17881361
- Abbott2008a pmid=18032406
- Finn2008 pmid=18292090
- Abbott2009a pmid=19181667
- Abbott2009b pmid=19181667
- Abbott2010a pmid=20851883
- Correia2010 pmid=20496884
- Abbott2011 pmid=21505233
- Pluvinage2011 pmid=22078560
- Abbott2012 pmid=22297983
- Pluvinage2013 pmid=23154168
- Abbott2013 pmid=24013861