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Difference between revisions of "User:Mario Murakami"
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| − | Mario Murakami is the scientific director of the Brazilian Biorenewables National Laboratory (since 2018) and former coordinator of the macromolecular crystallography village at the Brazilian National Center for Research in Energy and Materials (2010-2017). He obtained Ph.D. degree in molecular biophysics (2006) from the State University of São Paulo with a split Ph.D. at the University of Hamburg and German Electron Synchrotron DESY. He worked with the structural elucidation of macromolecular complexes involved in the inhibition and activation of enzymes during his post-docs at UNESP and Rutgers University. His current research interests encompass the discovery and mechanistic understanding of CAZymes and the genetic engineering of filamentous fungi for enzyme production. He has contributed to structure and function studies of CAZymes from families GH1 <cite>Giuseppe2012, Crespim2016, Santos2016, Zanphorlin2016, Toyama2018, Santos2019</cite>, GH2 <cite>Domingues2018</cite>, GH5 <cite>Santos2012a, Santos2012b, Alvarez2013a, Santos2015, | + | Mario Murakami is the scientific director of the Brazilian Biorenewables National Laboratory (since 2018) and former coordinator of the macromolecular crystallography village at the Brazilian National Center for Research in Energy and Materials (2010-2017). He obtained Ph.D. degree in molecular biophysics (2006) from the State University of São Paulo with a split Ph.D. at the University of Hamburg and German Electron Synchrotron DESY. He worked with the structural elucidation of macromolecular complexes involved in the inhibition and activation of enzymes during his post-docs at UNESP and Rutgers University. His current research interests encompass the discovery and mechanistic understanding of CAZymes and the genetic engineering of filamentous fungi for enzyme production. He has contributed to structure and function studies of CAZymes from families GH1 <cite>Giuseppe2012, Crespim2016, Santos2016, Zanphorlin2016, Toyama2018, Santos2019</cite>, GH2 <cite>Domingues2018</cite>, GH5 <cite>Santos2012a, Santos2012b, Alvarez2013a, Santos2015, Ruiz2016, Rosa2019</cite>, GH7 <cite>Segato2012</cite>, GH8 <cite>Scapin2017</cite>, GH10 <cite>Santos2010, Alvarez2013b, Santos2014</cite>, GH11<cite>Murakami2005, Ribeiro2011, Diogo2015, Hoffmam2016 </cite>, GH12<cite>Damasio2012, Furtado2015, Segato2017</cite>, GH16 <cite>Cota2011, Cota2013</cite>, GH39<cite></cite>, GH43<cite></cite>, GH42<cite></cite>, GH45<cite></cite>, GH51<cite></cite>, GH54<cite></cite>, GH57<cite></cite>, GH128 <cite></cite>and AA9<cite></cite>. Recently, his group rationally engineered a publicly available strain (Trichoderma reesei RUT-C30), which can secrete more than 80 g/L of proteins, mostly CAZymes, using a low-cost and byproduct-based bioprocess. |
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#Furtado2015 pmid=25605422 | #Furtado2015 pmid=25605422 | ||
#Segato2017 pmid=28088615 | #Segato2017 pmid=28088615 | ||
| − | # | + | #Cota2011 pmid=21352806 |
| + | #Cota2013 pmid=23459129 | ||
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Revision as of 02:02, 17 June 2020
Mario Murakami is the scientific director of the Brazilian Biorenewables National Laboratory (since 2018) and former coordinator of the macromolecular crystallography village at the Brazilian National Center for Research in Energy and Materials (2010-2017). He obtained Ph.D. degree in molecular biophysics (2006) from the State University of São Paulo with a split Ph.D. at the University of Hamburg and German Electron Synchrotron DESY. He worked with the structural elucidation of macromolecular complexes involved in the inhibition and activation of enzymes during his post-docs at UNESP and Rutgers University. His current research interests encompass the discovery and mechanistic understanding of CAZymes and the genetic engineering of filamentous fungi for enzyme production. He has contributed to structure and function studies of CAZymes from families GH1 [1, 2, 3, 4, 5, 6], GH2 [7], GH5 [8, 9, 10, 11, 12, 13], GH7 [14], GH8 [15], GH10 [16, 17, 18], GH11[19, 20, 21, 22], GH12[23, 24, 25], GH16 [26, 27], GH39[], GH43[], GH42[], GH45[], GH51[], GH54[], GH57[], GH128 []and AA9[]. Recently, his group rationally engineered a publicly available strain (Trichoderma reesei RUT-C30), which can secrete more than 80 g/L of proteins, mostly CAZymes, using a low-cost and byproduct-based bioprocess.
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