5 June 2019: New and cool beta(1,2)-glucanases of GH162:
Today Author Nobukiyo Tanaka
and Responsible Curator Masahiro Nakajima
completed the Glycoside Hydrolase Family 162
page in CAZypedia
. As its high number would imply, GH162
is one of the newest families in the CAZy classification, of which the first example has been elegantly characterized in 2019 by Drs. Tanaka
and their colleagues. GH162
is a tiny family of mostly fungal members, which has structural and mechanistic commonality with GH144
, and may be distantly related to GH8
GH-M) and GH15
GH-L). Learn more about all of these families on their respective pages
14 May 2019: Starch... it's not over yet: Two new families of starch-binding CBMs, CBM82 and CBM83, have joined the CAZypedia ranks. These CBMs are both found in an enormous multi-modular cell-wall anchored enzyme from a gut bacterium. The pages were both authored by Darrell Cockburn with Nicole Koropatkin acting as responsible curator. Learn more about the new starch-binding CBM82 and CBM83 families on their respective pages.
28 February 2019: CE9 is CE page #2!: Graduate student Alex Anderson has completed CAZypedia's second Carbohydrate Esterase (CE) family page, Carbohydrate Esterase Family 9, which was Curator Approved by his supervisor Michael Suits today. CE9 enzymes are metal-dependent N-acetylglucosamine 6-phosphate deacetylases that function in peptidoglycan recycling in bacteria. CE9 is a huge family, currently comprising over 10,000 members (nearly all are from bacteria), which underscores their biological importance. Alex and Mike completed CAZypedia's first CE family page, CE4 earlier this month, and we thank them for these seminal expansions of of our resource. Learn more about the structure and mechanism of metal-dependent deamidases here: CE9, CE4.
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