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Difference between revisions of "Polysaccharide epimerases"
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| + | === Classification === | ||
| − | === | + | === Mannuronan C5-epimerases === |
Mannuronan C5-epimerases are a group of enzymes that catalyze epimerization at the polymer-level of β-<font style="font-feature-settings: 'smcp'">d</font>-mannuronic acid residues (hereafter denoted M) into α-<font style="font-feature-settings: 'smcp'">l</font>-guluronic acid residues (hereafter denoted G) in alginate <cite>haug1969, larsen1971, haug1971</cite>. Alginate is an anionic polysaccharide made by brown seaweeds, some species of red algae, and the gram-negative bacterial genera ''Pseudomonas'' and ''Azotobacter'' <cite>Stanford1883, Gorin1966, Linker1966, govan1981, okazaki1982</cite>. The function of alginate in the different organisms are various, and related to structure, protection and surface adhesion <cite>painter1983, campos1996, Pier2001, Harmsen2010 </cite>. Alginate is a copolymer of the two 1-4 linked epimers <cite> Hirst1939, fischer1955, Drummond1962 </cite>, and by changing the composition of the two monomers the epimerases fine-tune the properties of the polymer <cite> Ertesvaag1999 </cite>. | Mannuronan C5-epimerases are a group of enzymes that catalyze epimerization at the polymer-level of β-<font style="font-feature-settings: 'smcp'">d</font>-mannuronic acid residues (hereafter denoted M) into α-<font style="font-feature-settings: 'smcp'">l</font>-guluronic acid residues (hereafter denoted G) in alginate <cite>haug1969, larsen1971, haug1971</cite>. Alginate is an anionic polysaccharide made by brown seaweeds, some species of red algae, and the gram-negative bacterial genera ''Pseudomonas'' and ''Azotobacter'' <cite>Stanford1883, Gorin1966, Linker1966, govan1981, okazaki1982</cite>. The function of alginate in the different organisms are various, and related to structure, protection and surface adhesion <cite>painter1983, campos1996, Pier2001, Harmsen2010 </cite>. Alginate is a copolymer of the two 1-4 linked epimers <cite> Hirst1939, fischer1955, Drummond1962 </cite>, and by changing the composition of the two monomers the epimerases fine-tune the properties of the polymer <cite> Ertesvaag1999 </cite>. | ||
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=== Product profiles === | === Product profiles === | ||
Revision as of 00:19, 8 April 2020
This page is currently under construction. This means that the Responsible Curator has deemed that the page's content is not quite up to CAZypedia's standards for full public consumption. All information should be considered to be under revision and may be subject to major changes.
- Author: ^^^Margrethe Gaardlos^^^ and ^^^Anne Tondervik^^^
- Responsible Curator: ^^^Finn Aachmann^^^
Introduction
Classification
Mannuronan C5-epimerases
Mannuronan C5-epimerases are a group of enzymes that catalyze epimerization at the polymer-level of β-d-mannuronic acid residues (hereafter denoted M) into α-l-guluronic acid residues (hereafter denoted G) in alginate [1, 2, 3]. Alginate is an anionic polysaccharide made by brown seaweeds, some species of red algae, and the gram-negative bacterial genera Pseudomonas and Azotobacter [4, 5, 6, 7, 8]. The function of alginate in the different organisms are various, and related to structure, protection and surface adhesion [9, 10, 11, 12]. Alginate is a copolymer of the two 1-4 linked epimers [13, 14, 15], and by changing the composition of the two monomers the epimerases fine-tune the properties of the polymer [16].
Product profiles
Main section 2
Whatevs...
References
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Stanford, Edw C C. (1883) On algin: a new substance obtained from some of the commoner species of marine algae. R. Anderson. NLM ID: 101217546
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Gorin, P. A. J. and Spencer, J. F. T. (1966) Exocellular alginic acid from Azotobacter vinelandii. Canadian Journal of Chemistry vol. 44, no. 9., pp. 993-998. [1]
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Okazaki, M., K. and Furuya, K. Tsukayam and K. Nisizawa. (1982) Isolation and Identification of Alginic Acid from a Calcareous Red Alga Serraticardia maxima. Botanica Marina, vol. 25, no. 3., pp. 123-131. [1]
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Painter, Terence J. (1983) Chapter 4 - Algal Polysaccharides. Edited by Gerald O. Aspinall. The Polysaccharides. New York: Academic Press. [1]
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Hirst, E. L. and Jones, J. K. N and Jones, Winifred Osman. (1939) 389. The structure of alginic acid. Part I [in en]. Journal of the Chemical Society, The Royal Society of Chemistry. Vol. 0, pp. 1880–1885. [1]
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Drummond, D W and Hirst, E L and Percival, Elizabeth. (1962) 232. The constitution of alginic acid. Journal of the Chemical Society, The Royal Society of Chemistry. Vol. 0, pp. 1208–1216. [1]
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Davies, G.J. and Sinnott, M.L. (2008) Sorting the diverse: the sequence-based classifications of carbohydrate-active enzymes. The Biochemist, vol. 30, no. 4., pp. 26-32. Download PDF version.