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Glycoside Hydrolase Family 64
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- Author: ^^^Julie Grondin^^^
- Responsible Curator: ^^^Harry Brumer^^^
Glycoside Hydrolase Family GH64 | |
Clan | GH-x |
Mechanism | inverting |
Active site residues | known |
CAZy DB link | |
http://www.cazy.org/GH64.html |
Substrate specificities
Content is to be added here.
Kinetics and Mechanism
Content is to be added here.
Catalytic Residues
Content is to be added here.
Three-dimensional structures
Content is to be added here.
Family Firsts
- First stereochemistry determination
- Laminaripentaose-producing beta-1,3-glucanase (LPHase) from Streptomyces matensis DIC-108.[1]
- First catalytic nucleophile identification
- Laminaripentaose-producing beta-1,3-glucanase (LPHase) from Streptomyces matensis DIC-108.[2]
- First general acid/base residue identification
- Laminaripentaose-producing beta-1,3-glucanase (LPHase) from Streptomyces matensis DIC-108.[2]
- First 3-D structure
- Laminaripentaose-producing beta-1,3-glucanase (LPHase) from Streptomyces matensis DIC-108.[2]
References
- Nishimura T, Bignon C, Allouch J, Czjzek M, Darbon H, Watanabe T, and Henrissat B. (2001). Streptomyces matensis laminaripentaose hydrolase is an 'inverting' beta-1,3-glucanase. FEBS Lett. 2001;499(1-2):187-90. DOI:10.1016/s0014-5793(01)02551-0 |
- Wu HM, Liu SW, Hsu MT, Hung CL, Lai CC, Cheng WC, Wang HJ, Li YK, and Wang WC. (2009). Structure, mechanistic action, and essential residues of a GH-64 enzyme, laminaripentaose-producing beta-1,3-glucanase. J Biol Chem. 2009;284(39):26708-15. DOI:10.1074/jbc.M109.010983 |