CAZypedia needs your help! We have many unassigned GH, PL, CE, AA, GT, and CBM pages in need of Authors and Responsible Curators.
Scientists at all career stages, including students, are welcome to contribute to CAZypedia. Read more here, and in the 10th anniversary article in Glycobiology.
New to the CAZy classification? Read this first.
*
Consider attending the 15th Carbohydrate Bioengineering Meeting in Ghent, 5-8 May 2024.
Difference between revisions of "General acid/base"
(Created page with ' * Author: Spencer Williams * Responsible Curator: Spencer Williams ---- == Overview == The term '''catalytic acid/base''' re…') |
|||
Line 1: | Line 1: | ||
− | |||
* Author: [[User:SpencerWilliams|Spencer Williams]] | * Author: [[User:SpencerWilliams|Spencer Williams]] | ||
Line 6: | Line 5: | ||
== Overview == | == Overview == | ||
− | The term ''' | + | The term '''general acid/base''' (also catalytic acid/base) refers to an amino acid residue in a [[glycoside hydrolase]] or a related enzyme that participates in the mechanism of hydrolysis by removing or adding a proton. The mechanism may be a [[retaining]] or [[inverting]] mechanism. General acid/base catalysis differs from specific acid/base catalysis as in the latter it is the solvent that acts as the acid or base. |
[[Image:Retaining_glycosidase_mechanism_1.png|centre]] | [[Image:Retaining_glycosidase_mechanism_1.png|centre]] | ||
− | ==Methods for indentifying the | + | ==Methods for indentifying the general acid/base== |
== References == | == References == |
Revision as of 19:01, 31 August 2009
- Author: Spencer Williams
- Responsible Curator: Spencer Williams
Overview
The term general acid/base (also catalytic acid/base) refers to an amino acid residue in a glycoside hydrolase or a related enzyme that participates in the mechanism of hydrolysis by removing or adding a proton. The mechanism may be a retaining or inverting mechanism. General acid/base catalysis differs from specific acid/base catalysis as in the latter it is the solvent that acts as the acid or base.