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Difference between revisions of "Glycoside Hydrolase Family 112"
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(New page: * Author: Motomitsu Kitaoka * Responsible Curator: Shinya Fushinobu ---- <div style="float:right"> {| {{Prettytable}} |- |{{Hl...) |
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== Substrate specificities == | == Substrate specificities == | ||
− | + | Normal 0 0 2 MicrosoftInternetExplorer4 This family contains beta-galactoside phosphorolyzing enzymes, β-1,3-D-galactosyl-D-hexososamine phosphorylase [1] and β-1,4-D-gaactosyl-L-rhamnose phosphorylase [2]. The former enzymes are subcategorized into galacto-''N''-biose phosphorylase, (GNBP) [3], lacto-''N''-biose I phosphorylase (LNBP) [4], and galacto-''N''-biose/lacto-''N''-biose I phosphorylase (GLNBP) [1,4,5] based on the substrate preference on galacto-''N''-biose (GNB, Gal-β1,3-GalNAc) and lacto-''N''-biose I (LNB, Gal-β1,3-GlcNAc) [4]. | |
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== Kinetics and Mechanism == | == Kinetics and Mechanism == |
Revision as of 01:13, 14 July 2009
Glycoside Hydrolase Family 112 | |
Clan | none |
Mechanism | inverting |
Active site residues | known |
CAZy DB link | |
http://www.cazy.org/fam/GH112.html |
Substrate specificities
Normal 0 0 2 MicrosoftInternetExplorer4 This family contains beta-galactoside phosphorolyzing enzymes, β-1,3-D-galactosyl-D-hexososamine phosphorylase [1] and β-1,4-D-gaactosyl-L-rhamnose phosphorylase [2]. The former enzymes are subcategorized into galacto-N-biose phosphorylase, (GNBP) [3], lacto-N-biose I phosphorylase (LNBP) [4], and galacto-N-biose/lacto-N-biose I phosphorylase (GLNBP) [1,4,5] based on the substrate preference on galacto-N-biose (GNB, Gal-β1,3-GalNAc) and lacto-N-biose I (LNB, Gal-β1,3-GlcNAc) [4].
Kinetics and Mechanism
Catalytic Residues
Three-dimensional structures
Family Firsts
- First sterochemistry determination
- First catalytic nucleophile identification
- First general acid/base residue identification
- First 3-D structure
- Cite some reference here, with a short explanation [1].