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Glycoside Hydrolase Family 55

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Glycoside Hydrolase Family 55
Clan none
Mechanism retaining/inverting
Active site residues known/not known
CAZy DB link
http://www.cazy.org/fam/GH55.html

Substrate specificities

Kinetics and Mechanism

Catalytic Residues

Three-dimensional structures

Family Firsts

First sterochemistry determination
Cite some reference here, with a short explanation.
First catalytic nucleophile identification
First general acid/base residue identification
First 3-D structure
β-1,3-Glucanase Lam55A from Phanerochaete chrysosporium K-3 by X-ray crystallography (PDB 3eqn and PDB 3eqo) [1].

References

  1. Ishida T, Fushinobu S, Kawai R, Kitaoka M, Igarashi K, and Samejima M. (2009). Crystal structure of glycoside hydrolase family 55 {beta}-1,3-glucanase from the basidiomycete Phanerochaete chrysosporium. J Biol Chem. 2009;284(15):10100-9. DOI:10.1074/jbc.M808122200 | PubMed ID:19193645 [REF1]