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Difference between revisions of "Polysaccharide Lyases"
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== Introduction == | == Introduction == | ||
| − | + | Polysaccharide lyases (PLs) cleave uronic acid-containing polysaccharides via a β-elimination mechanism to generate an unsaturated hexenuronic acid residue and a new reducing end at the point of cleavage. PLs have been grouped into families and subfamilies within the Carbohydrate-Active Enzyme (CAZy) framework <cite>Lombard2010</cite>. Please see the following reviews on PL classification, specificities, and structures <cite>Lombard2010 Garron2010</cite> | |
== References == | == References == | ||
Revision as of 17:44, 28 November 2013
This page is currently under construction. This means that the Responsible Curator has deemed that the page's content is not quite up to CAZypedia's standards for full public consumption. All information should be considered to be under revision and may be subject to major changes.
- Author: ^^^Michael Suits^^^ and ^^^Wade Abbott^^^
- Responsible Curator: ^^^Spencer Williams^^^
Introduction
Polysaccharide lyases (PLs) cleave uronic acid-containing polysaccharides via a β-elimination mechanism to generate an unsaturated hexenuronic acid residue and a new reducing end at the point of cleavage. PLs have been grouped into families and subfamilies within the Carbohydrate-Active Enzyme (CAZy) framework [1]. Please see the following reviews on PL classification, specificities, and structures [1, 2]
References
- Lombard V, Bernard T, Rancurel C, Brumer H, Coutinho PM, and Henrissat B. (2010). A hierarchical classification of polysaccharide lyases for glycogenomics. Biochem J. 2010;432(3):437-44. DOI:10.1042/BJ20101185 |
- Garron ML and Cygler M. (2010). Structural and mechanistic classification of uronic acid-containing polysaccharide lyases. Glycobiology. 2010;20(12):1547-73. DOI:10.1093/glycob/cwq122 |