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Difference between revisions of "User:Roland Ludwig"

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Roland Ludwig graduated from BOKU - University of Natural Resources and Life Sciences, Vienna with a masters degree in biotechnology and completed his doctoral studies under the supervision of Dietmar Haltrich in 2004. He worked as a senior & key researcher for the Austrian Centre of Industrial Biotechnology until 2009, when starting a postdoctoral internship at Lund University with bioelectrochemist Lo Gorton. Since 2011, he is permanently associated with BOKU and works on cofactor-dependent oxidoreductases such as laccases [[AA2]]and GMC-oxidoreductases [[AA3]]. The research focuses on the screening, production, and characterisation  of oxidoreductases to understand their physiological roles and their engineering and application in biocatalysis and biosensors [http://www.ludiglab.eu].
 
 
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Roland Ludwig graduated from BOKU - University of Natural Resources and Life Sciences, Vienna with a masters degree in biotechnology and completed his doctoral studies under the supervision of Dietmar Haltrich in 2004. He worked as a senior & key researcher for the Austrian Centre of Industrial Biotechnology until 2009, when starting a postdoctoral internship at Lund University with bioelectrochemist Lo Gorton. Since 2011, he is permanently associated with BOKU and works on cofactor-dependent oxidoreductases such as laccases [[AA7]]and GMC-oxidoreductases .
 
 
 
The work focused on structural studies of glycoside hydrolases from families , [[GH11]] and [[GH12]]. In 1999 she obtained a personal EMBO fellowship to join the group of ^^^Bernard Henrissat^^^ at the [http://www.cnrs.fr/ CNRS] laboratory [http://www.afmb.univ-mrs.fr/ Architecture et Fonction des Macromolecules Biologiques]. She is currently permanent research engineer in the group of Yves Bourne at the [http://www.afmb.univ-mrs.fr/ AFMB] laboratory. She has determined the crystal structures of
 
 
 
* [[GH7]] ''Fusarium oxysporum'' endoglucanase <cite>Sulzenbacher1996 Sulzenbacher1997a</cite>
 
* [[GH11]] ''Bacillus pumilus'' xylanase
 
* [[GH12]] ''Streptomyces lividans'' endoglucanase <cite>Sulzenbacher1997b Sulzenbacher1999</cite>
 
* [[GH29]] ''Thermotoga maritima'' α-fucosidase <cite>Sulzenbacher2004</cite>
 
* [[GH109]] ''Elizabethkingia meningosepticum'' α-N-acetylgalactosaminidase <cite>Liu2007</cite>
 
  
  

Revision as of 23:17, 3 May 2018

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Roland Ludwig graduated from BOKU - University of Natural Resources and Life Sciences, Vienna with a masters degree in biotechnology and completed his doctoral studies under the supervision of Dietmar Haltrich in 2004. He worked as a senior & key researcher for the Austrian Centre of Industrial Biotechnology until 2009, when starting a postdoctoral internship at Lund University with bioelectrochemist Lo Gorton. Since 2011, he is permanently associated with BOKU and works on cofactor-dependent oxidoreductases such as laccases AA2and GMC-oxidoreductases AA3. The research focuses on the screening, production, and characterisation of oxidoreductases to understand their physiological roles and their engineering and application in biocatalysis and biosensors [1].



  1. Sulzenbacher G, Driguez H, Henrissat B, Schülein M, and Davies GJ. (1996). Structure of the Fusarium oxysporum endoglucanase I with a nonhydrolyzable substrate analogue: substrate distortion gives rise to the preferred axial orientation for the leaving group. Biochemistry. 1996;35(48):15280-7. DOI:10.1021/bi961946h | PubMed ID:8952478 [Sulzenbacher1996]
  2. Gilbert HJ, Stålbrand H, and Brumer H. (2008). How the walls come crumbling down: recent structural biochemistry of plant polysaccharide degradation. Curr Opin Plant Biol. 2008;11(3):338-48. DOI:10.1016/j.pbi.2008.03.004 | PubMed ID:18430603 [Gilbert2008]

All Medline abstracts: PubMed