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Glycoside Hydrolase Family 69

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This family has been deleted from the CAZy classification. A specific explanation may be found below.

GH69 is a deleted family

Entries in GH69 were transferred to Polysaccharide Lyase Family 16 when it was shown that polysaccharide cleavage occurred via a beta elimination, rather than glycosidic bond hydrolysis [1, 2].


  1. Baker JR, Dong S, and Pritchard DG. (2002). The hyaluronan lyase of Streptococcus pyogenes bacteriophage H4489A. Biochem J. 2002;365(Pt 1):317-22. DOI:10.1042/BJ20020149 | PubMed ID:12071858 [Baker2002]
  2. Smith NL, Taylor EJ, Lindsay AM, Charnock SJ, Turkenburg JP, Dodson EJ, Davies GJ, and Black GW. (2005). Structure of a group A streptococcal phage-encoded virulence factor reveals a catalytically active triple-stranded beta-helix. Proc Natl Acad Sci U S A. 2005;102(49):17652-7. DOI:10.1073/pnas.0504782102 | PubMed ID:16314578 [Smith2005]

All Medline abstracts: PubMed

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