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User:Alex Anderson

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Alex Anderson recieved his BScH from Wilfrid Laurier University (Canada) in 2017, and began his foray into microbiology as a diagnostic laboratory technician at the Public Health Ontario Laboratories where he became fascinated with microbial cell surface structure and function. Alex completed his MSc in 2019 the lab of Dr. Joel Weadge, alongside Michael Suits, at WLU where he studied the structure and function of CAZymes responsible for the biosynthesis, modification and export of cellulosic materials involved in biofilm formation in Gram-negative pathogens. Alex is currently a PhD candidate in the lab of Dr. Anthony J. Clarke at the University of Guelph where he studies the mechanism of peptidoglycan O-acetylation in Gram-negative bacteria.

Alex and colleagues have demonstrated the structures of:

CAZy-unclassified Escherichia coli phosphoethanolamine transferase BcsG (6PCZ/6PD0) [1]

GH5 Clostridioides difficile endo-β-glucanase CcsZ (6UJE/6UJF) [2]

  1. Anderson AC, Burnett AJN, Hiscock L, Maly KE, and Weadge JT. (2020) The Escherichia coli cellulose synthase subunit G (BcsG) is a Zn2+-dependent phosphoethanolamine transferase. J Biol Chem. 295, 6225-6235. DOI:10.1074/jbc.RA119.011668 | PubMed ID:32152228 | HubMed [Anderson2020]
  2. Scott W, Lowrance B, Anderson AC, and Weadge JT. (2020) Identification of the Clostridial cellulose synthase and characterization of the cognate glycosyl hydrolase, CcsZ. PLoS One. 15, e0242686. DOI:10.1371/journal.pone.0242686 | PubMed ID:33264329 | HubMed [Scott2020]
All Medline abstracts: PubMed | HubMed