New to the CAZy classification? Read this first.
Want to learn more about CAZypedia? Read the CAZypedia 10th anniversary article in Glycobiology.
In 2009 I obtained my M.Sc in Biotechnology for Veterinary Activities at University of Naples "Federico II", Italy. My PhD in Biological and Biomedical Sciences at Technical University of Lisbon (Portugal), University of Veterinary Medicine was completed in 2015 under the supervision of Dr. Carlos Fontes. My PhD project was 'WallTraC Marie Curie Initial Training Network' and the focus of this work was the structure and function of novel CAZymes and CBMs involved in Plant Cell Wall degradation [ 1, 2, 3 ]. I’m currently a PostDoc mentored by Prof. Harry Gilbert at University of Newcastle, UK. My research is focused on the microbial degradation and utilization of complex pectins by Bacteroides in the human intestine [ 4 ].
- Luís AS, Venditto I, Temple MJ, Rogowski A, Baslé A, Xue J, Knox JP, Prates JA, Ferreira LM, Fontes CM, Najmudin S, and Gilbert HJ. Understanding how noncatalytic carbohydrate binding modules can display specificity for xyloglucan. J Biol Chem. 2013 Feb 15;288(7):4799-809. DOI: 10.1074/jbc.M112.432781 | PMID 23229556 | HubMed [Luis2013]
- Venditto I, Najmudin S, Luís AS, Ferreira LM, Sakka K, Knox JP, Gilbert HJ, Fontes CM. J Biol Chem. 2015 Apr 24;290(17):10572-86 DOI: 10.1074/jbc.M115.637827 | PMID 25713075 | HubMed [Venditto2015]
- Venditto I, Luis AS, Rydahl M, Schückel J, Fernandes VO, Vidal-Melgosa S, Bule P, Goyal A, Pires VM, Dourado CG, Ferreira LM, Coutinho PM, Henrissat B, Knox JP, Baslé A, Najmudin S, Gilbert HJ, Willats WG, and Fontes CM. Complexity of the Ruminococcus flavefaciens cellulosome reflects an expansion in glycan recognition. Proc Natl Acad Sci U S A. 2016 Jun 28;113(26):7136-41. DOI: 10.1073/pnas.1601558113 | PMID 27298375 | HubMed [Venditto2016]
- Ndeh D, Rogowski A, Cartmell A, Luis AS, Baslé A, Gray J, Venditto I, Briggs J, Zhang X, Labourel A, Terrapon N, Buffetto F, Nepogodiev S, Xiao Y, Field RA, Zhu Y, O'Neil MA, Urbanowicz BR, York WS, Davies GJ, Abbott DW, Ralet MC, Martens EC, Henrissat B, and Gilbert HJ. Complex pectin metabolism by gut bacteria reveals novel catalytic functions. Nature. 2017 Apr 6;544(7648):65-70. DOI: 10.1038/nature21725 | PMID 28329766 | HubMed [Ndeh2017]