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User:Marie-Line Garron
After a Ph.D. obtained in 2007 from the University of Montpellier (France), I joined Mirek Cygler's group, as postdoctoral student, at the Biotechnological Reasearch Institut (Montreal, QC, Canada). My postdoctoral research focused on the structure and function of CAZymes involved in synthesis and degradation of glycosaminoglycans (GAGs), and in particular on Polysaccharide Lyases on which I wrote two reviews.
In 2010, I joined the glycogenomic group, led by Bernard Henrissat at AFMB laboratory (Marseille, France), as postdoctoral researcher in charge of strengthening the functional and structural side of the team. I then obtained a permanent position as Assistant Professor in Aix-Marseille University in 2011.
I currently manage the updates of structural and functional information in the CAZy database. My personal research interests are with the biochemical and structural characterization of distant members of CAZy families and with the discovery of new CAZymes families.
Reviews
- Garron ML and Henrissat B. (2019). The continuing expansion of CAZymes and their families. Curr Opin Chem Biol. 2019;53:82-87. DOI:10.1016/j.cbpa.2019.08.004 |
- Garron ML and Cygler M. (2014). Uronic polysaccharide degrading enzymes. Curr Opin Struct Biol. 2014;28:87-95. DOI:10.1016/j.sbi.2014.07.012 |
- Garron ML and Cygler M. (2010). Structural and mechanistic classification of uronic acid-containing polysaccharide lyases. Glycobiology. 2010;20(12):1547-73. DOI:10.1093/glycob/cwq122 |
Publications
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- Han YH, Garron ML, Kim HY, Kim WS, Zhang Z, Ryu KS, Shaya D, Xiao Z, Cheong C, Kim YS, Linhardt RJ, Jeon YH, and Cygler M. (2009). Structural snapshots of heparin depolymerization by heparin lyase I. J Biol Chem. 2009;284(49):34019-27. DOI:10.1074/jbc.M109.025338 |
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