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Difference between revisions of "Polysaccharide Lyase Family 32"
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| − | + | === PL32 is a deleted family === | |
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The PL32 family was created following the functional characterization of the ORF “HMPREF1071_02769” from ''Bacteroides salyersiae ''CL02T12C01 (EIY62149.1), which showed endo-mannuronan lyase activity ([https://www.enzyme-database.org/query.php?ec=4.2.2.3 EC 4.2.2.3]) <cite>Helbert2019</cite>. Shortly afterwards, the sequence was <u>'''reclassified'''</u> as [http://www.cazy.org/PL0.html PL_nc] on the basis of structural modelling revealing that the catalytic domain was restricted to the N-terminal domain <cite>Drula2022</cite>. The small number of sequences and the proximity to the [[PL14]] and [[PL36]] families do not allow the creation of a new PL family. | The PL32 family was created following the functional characterization of the ORF “HMPREF1071_02769” from ''Bacteroides salyersiae ''CL02T12C01 (EIY62149.1), which showed endo-mannuronan lyase activity ([https://www.enzyme-database.org/query.php?ec=4.2.2.3 EC 4.2.2.3]) <cite>Helbert2019</cite>. Shortly afterwards, the sequence was <u>'''reclassified'''</u> as [http://www.cazy.org/PL0.html PL_nc] on the basis of structural modelling revealing that the catalytic domain was restricted to the N-terminal domain <cite>Drula2022</cite>. The small number of sequences and the proximity to the [[PL14]] and [[PL36]] families do not allow the creation of a new PL family. | ||
Revision as of 15:40, 1 October 2024
This page has been approved by the Responsible Curator as essentially complete. CAZypedia is a living document, so further improvement of this page is still possible. If you would like to suggest an addition or correction, please contact the page's Responsible Curator directly by e-mail.
This family has been deleted from the CAZy classification. A specific explanation may be found below.
PL32 is a deleted family
The PL32 family was created following the functional characterization of the ORF “HMPREF1071_02769” from Bacteroides salyersiae CL02T12C01 (EIY62149.1), which showed endo-mannuronan lyase activity (EC 4.2.2.3) [1]. Shortly afterwards, the sequence was reclassified as PL_nc on the basis of structural modelling revealing that the catalytic domain was restricted to the N-terminal domain [2]. The small number of sequences and the proximity to the PL14 and PL36 families do not allow the creation of a new PL family.
References
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- Error fetching PMID 30850540:
- Error fetching PMID 34850161:
| CAZy DB links | |
| https://www.cazy.org/PL32.html |