CAZypedia celebrates the life of Senior Curator Emeritus Harry Gilbert, a true giant in the field, who passed away in September 2025.


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Difference between revisions of "Template:News"

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'''6 August 2015:''' ''Live from the Cellulase/CAZyme GRC:'' ''CAZypedia'' marches on with the completion of the '''[[Polysaccharide Lyase Family 1]]''' today by [[Responsible Curator]] and [[Author]] '''[[User:Richard Pickersgill|Richard Pickersgill]]''', with additional editing by [[Polysaccharide Lyase Families]] coordinator '''[[User:Wade Abbott|Wade Abbott]]''''''[[PL1]]''' contains pectate lyases from microbes and plants, which are key enzymes in plant cell wall remodelling/break-down.  The solution of the crystal structure of a pectate lyase C from the plant pathogen ''Erwinia chrysanthemi'' was the first to reveal the parallel beta-helix as a novel protein fold that is now known to serve as the scaffold of other pectinolytic enzymes, including pectin hydrolases ([[GH28]]) and pectin methylesterases ([[CE8]]).  ''Read more about the discovery of pectate lyases and the enzymology and crystallography of [[PL1]] [[PL|here]].''
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'''31 October 2025:''' ''A spooktacular addition to the CAZypedia family!'' Come and say 'Boo!' to the frighteningly well written '''[[CBM13]]''' ''CAZypedia'' page.  The '''[[CBM13]]''' family is a '''[[Carbohydrate-binding_modules#Blurred Lines: CBMs, Lectins and Outliers|lectin-like CBM family]]'''. Its first characterized members were lectins, including the B chain from the highly toxic [https://en.wikipedia.org/wiki/Ricin ricin] toxin from ''Ricinus communis''.  This spine tingling read was authored by '''[[User:Scott Mazurkewich|Scott Mazurkewich]]''' and '''[[User:Lauren McKee|Lauren McKee]]''' who also acted as responsible curator. ''Come and visit the scariest of ''CAZypedia'' CBM pages, '''[[CBM13|here!]]'''...  if you dare...''
 
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'''28 July 2015:'''  '''''100 GH FAMILIES!!!''''' We are extremely pleased to announce that ''CAZypedia'' has reached the key milestone of 100 [[Curator Approved]] [[Glycoside Hydrolase Families|Glycoside Hydrolase Family]] pages today, thanks to the completion of the '''[[Glycoside Hydrolase Family 12]]''' page by '''[[User:Gerlind Sulzenbacher|Gerlind Sulzenbacher]]'''.  '''[[GH12]]''' is one of the classic "cellulase" families ([http://www.ncbi.nlm.nih.gov/pubmed/1886523?dopt=Abstract formerly known as cellulase family H]) defined early in the history of the CAZy classification; [[GH12]] is now known to comprise both microbial endo-glucanases and endo-xyloglucanases. The completion of this page is especially timely in advance of the upcoming [http://www.grc.org/programs.aspx?id=12846 2015 GRC on Cellulosomes, Cellulases & Other Carbohydrate Modifying Enzymes], happening next week. [[User:Gerlind Sulzenbacher|Gerlind]] performed the seminal crystallography in this family (under the mentorship of [[User:Gideon Davies|Gideon Davies]]), and we would especially like to thank her for producing an excellent summary and series of figures for the "[[Glycoside_Hydrolase_Family_12#Three-dimensional_structures|Three-dimensional structures]]" section.
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'''29 July 2025:'''  ''[[CBM91]] is in the news!'' The xylan binding '''[[CBM91]]''' family ''CAZypedia'' page is up and running.  Appended to mainly [[GH43]] xylanases this [[CBM91]] family drives interaction with substrate. The [[CBM91]] page was authored by '''[[User:Daichi Ito|Daichi Ito]]''' who also discovered the initial xylan-binding function which resulted in the creation of the [[CBM91]] CAZy family. ''Read up on this industrially interesting '''[[CBM91]]''' family '''[[CBM91|here]]'''.''
 
 
 
 
''The [[Board of Curators]] would also like to take the opportunity of this key milestone to express our sincere gratitude to our many expert [[:Category:Contributors|Contributors]] for their time and dedication to building ''CAZypedia'' as a community-based resource [[:CAZypedia:History|over the past 8 years]]. In addition to the [[Glycoside Hydrolase Families|100 Curator Approved GH pages]], ''CAZypedia'' also currently contains [[Polysaccharide_Lyase_Families|5 PL Family pages]], [[Auxiliary Activity Families|2 AA Family pages]], [[Glycosyltransferase Families|2 GT Family pages]], [[Carbohydrate Binding Module Families|10 CBM Family pages]], and [[Lexicon|22 Lexicon pages]]!''
 
 
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Latest revision as of 10:50, 3 November 2025

31 October 2025: A spooktacular addition to the CAZypedia family! Come and say 'Boo!' to the frighteningly well written CBM13 CAZypedia page. The CBM13 family is a lectin-like CBM family. Its first characterized members were lectins, including the B chain from the highly toxic ricin toxin from Ricinus communis. This spine tingling read was authored by Scott Mazurkewich and Lauren McKee who also acted as responsible curator. Come and visit the scariest of CAZypedia CBM pages, here!... if you dare...


29 July 2025: CBM91 is in the news! The xylan binding CBM91 family CAZypedia page is up and running. Appended to mainly GH43 xylanases this CBM91 family drives interaction with substrate. The CBM91 page was authored by Daichi Ito who also discovered the initial xylan-binding function which resulted in the creation of the CBM91 CAZy family. Read up on this industrially interesting CBM91 family here.