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User:Gabriela Persinoti

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Gabriela Persinoti is the head of Integrative Omics team of the Brazilian Biorenewables National Laboratory LNBR, from Brazilian National Center for Research in Energy and Materials CNPEM (since 2020). She obtained her B.Sc. in Biomedical Informatics from the University of São Paulo (2006) and completed her PhD in Genetics (2012) at the Medical School of Ribeirão Preto (University of São Paulo). Her research interests are focused on the invetigation of microbiomes from diverse environments for the discovery of novel enzymes.

She has contributed to the investigation of CAZymes from families GH26 #Mandelli2020, GH39 , and GH128.


  1. Mandelli F, de Morais MAB, de Lima EA, Oliveira L, Persinoti GF, and Murakami MT. (2020). Spatially remote motifs cooperatively affect substrate preference of a ruminal GH26-type endo-β-1,4-mannanase. J Biol Chem. 2020;295(15):5012-5021. DOI:10.1074/jbc.RA120.012583 | PubMed ID:32139511 [Mandelli2020]
  2. de Morais MAB, Polo CC, Domingues MN, Persinoti GF, Pirolla RAS, de Souza FHM, Correa JBL, Dos Santos CR, and Murakami MT. (2020). Exploring the Molecular Basis for Substrate Affinity and Structural Stability in Bacterial GH39 β-Xylosidases. Front Bioeng Biotechnol. 2020;8:419. DOI:10.3389/fbioe.2020.00419 | PubMed ID:32500063 [Morais2020]
  3. Santos CR, Costa PACR, Vieira PS, Gonzalez SET, Correa TLR, Lima EA, Mandelli F, Pirolla RAS, Domingues MN, Cabral L, Martins MP, Cordeiro RL, Junior AT, Souza BP, Prates ÉT, Gozzo FC, Persinoti GF, Skaf MS, and Murakami MT. (2020). Structural insights into β-1,3-glucan cleavage by a glycoside hydrolase family. Nat Chem Biol. 2020;16(8):920-929. DOI:10.1038/s41589-020-0554-5 | PubMed ID:32451508 [Santos2020]
  4. Cabral L, Persinoti GF, Paixão DAA, Martins MP, Morais MAB, Chinaglia M, Domingues MN, Sforca ML, Pirolla RAS, Generoso WC, Santos CA, Maciel LF, Terrapon N, Lombard V, Henrissat B, and Murakami MT. (2022). Gut microbiome of the largest living rodent harbors unprecedented enzymatic systems to degrade plant polysaccharides. Nat Commun. 2022;13(1):629. DOI:10.1038/s41467-022-28310-y | PubMed ID:35110564 [Cabral2022]
  5. Cordeiro RL, Santos CR, Domingues MN, Lima TB, Pirolla RAS, Morais MAB, Colombari FM, Miyamoto RY, Persinoti GF, Borges AC, de Farias MA, Stoffel F, Li C, Gozzo FC, van Heel M, Guerin ME, Sundberg EJ, Wang LX, Portugal RV, Giuseppe PO, and Murakami MT. (2023). Mechanism of high-mannose N-glycan breakdown and metabolism by Bifidobacterium longum. Nat Chem Biol. 2023;19(2):218-229. DOI:10.1038/s41589-022-01202-4 | PubMed ID:36443572 [Cordeiro2023]

All Medline abstracts: PubMed