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Auxiliary Activity Family 10
This page is currently under construction. This means that the Responsible Curator has deemed that the page's content is not quite up to CAZypedia's standards for full public consumption. All information should be considered to be under revision and may be subject to major changes.
- Author: ^^^Vincent Eijsink^^^ and ^^^Gustav Vaaje-Kolstad^^^
- Responsible Curator: ^^^Vincent Eijsink^^^
Auxiliary Activity Family 10 | |
Clan | none, structurally related to AA9 |
Mechanism | lytic oxidase |
Active site residues | mononuclear copper ion |
CAZy DB link | |
http://www.cazy.org/AA10.html |
Substrate specificities
Content is to be added here. In the meantime, please see these references for an essential introduction to the CAZy classification system: [1, 2].
Kinetics and Mechanism
Content is to be added here.
Catalytic Residues
Content is to be added here.
Three-dimensional structures
Content is to be added here.
Family Firsts
- First stereochemistry determination
- Content is to be added here.
- First catalytic nucleophile identification
- Content is to be added here.
- First general acid/base residue identification
- Content is to be added here.
- First 3-D structure
- CBP21, the single AA10-type LPMO from the Gram negative bacterium Serratia marcescens. PDB identifier: [2BEM]http://www.pdb.org/pdb/explore/explore.do?structureId=2bem
References
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Davies, G.J. and Sinnott, M.L. (2008) Sorting the diverse: the sequence-based classifications of carbohydrate-active enzymes. Biochem. J. (BJ Classic Paper, online only). DOI: 10.1042/BJ20080382
- Cantarel BL, Coutinho PM, Rancurel C, Bernard T, Lombard V, and Henrissat B. (2009). The Carbohydrate-Active EnZymes database (CAZy): an expert resource for Glycogenomics. Nucleic Acids Res. 2009;37(Database issue):D233-8. DOI:10.1093/nar/gkn663 |