CAZypedia needs your help! We have many unassigned GH, PL, CE, AA, GT, and CBM pages in need of Authors and Responsible Curators.
Scientists at all career stages, including students, are welcome to contribute to CAZypedia. Read more here, and in the 10th anniversary article in Glycobiology.
New to the CAZy classification? Read this first.
*
Consider attending the 15th Carbohydrate Bioengineering Meeting in Ghent, 5-8 May 2024.
Glycoside Hydrolase Family 121
This page is currently under construction. This means that the Responsible Curator has deemed that the page's content is not quite up to CAZypedia's standards for full public consumption. All information should be considered to be under revision and may be subject to major changes.
- Author: ^^^Kiyotaka Fujita^^^
- Responsible Curator: ^^^Shinya Fushinobu^^^
Glycoside Hydrolase Family GH121 | |
Clan | GH-x |
Mechanism | retaining |
Active site residues | known/not known |
CAZy DB link | |
http://www.cazy.org/GH121.html |
Substrate specificities
This family of glycoside hydrolases contains β-L-arabinobiosidase, which was recently established for HypBA2 from Bifidobacterium longum JCM 1217[1].
Kinetics and Mechanism
HypBA2 is a retaining enzyme.by measurement of glycosyl transfer reactions to methanol
Catalytic Residues
Content is to be added here.
Three-dimensional structures
Content is to be added here.
Family Firsts
- First stereochemistry determination
- This was determined with HypBA2 enzyme using the 1H-NMR and 13C-NMR spectra to identify the transglycosylation product β-Ara2-OMe.
- First catalytic nucleophile identification
- Content is to be added here.
- First general acid/base residue identification
- Content is to be added here.
- First 3-D structure
- Content is to be added here.