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User:Darryl Jones

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After completing graduate studies at the University of Waterloo in the Department of Biology, Darryl joined the group of Dr. Wade Abbott at the Agriculture and Agri-Food CanadaLethbridge Research and Development Centre. As a member of Dr. Abbott's research team Darryl has been engaged in the identification and characterization of CAZymes from the intestinal microbiome, and the development of technologies involving carbohydrate modification for agricultural and intestinal health applications.

Darryl has contributed to studies of CAZymes from the following families:

Glycoside Hydrolases

  • GH39 from Neocallimastrix frontalis and Piromyces rhizinflatus [1].

Polysaccharide Lyases

  • PL2 from Yersinia enterocolitica and Vibrio vulnificus [2].



References

  1. Jones DR, Uddin MS, Gruninger RJ, Pham TTM, Thomas D, Boraston AB, Briggs J, Pluvinage B, McAllister TA, Forster RJ, Tsang A, Selinger LB, and Abbott DW. (2017) Discovery and characterization of family 39 glycoside hydrolases from rumen anaerobic fungi with polyspecific activity on rare arabinosyl substrates. J Biol Chem. 292, 12606-12620. DOI:10.1074/jbc.M117.789008 | PubMed ID:28588026 | HubMed [Jones2017]
  2. McLean R, Hobbs JK, Suits MD, Tuomivaara ST, Jones DR, Boraston AB, and Abbott DW. (2015) Functional Analyses of Resurrected and Contemporary Enzymes Illuminate an Evolutionary Path for the Emergence of Exolysis in Polysaccharide Lyase Family 2. J Biol Chem. 290, 21231-43. DOI:10.1074/jbc.M115.664847 | PubMed ID:26160170 | HubMed [McLean2015]
All Medline abstracts: PubMed | HubMed