CAZypedia celebrates the life of Senior Curator Emeritus Harry Gilbert, a true giant in the field, who passed away in September 2025.
CAZypedia needs your help!
We have many unassigned pages in need of Authors and Responsible Curators. See a page that's out-of-date and just needs a touch-up? - You are also welcome to become a CAZypedian. Here's how.
Scientists at all career stages, including students, are welcome to contribute.
Learn more about CAZypedia's misson here and in this article. Totally new to the CAZy classification? Read this first.
User:Johan Larsbrink
Associate Professor at the Department of Life Sciences, Chalmers University of Technology.
Background
I obtained a MSc degree in Biotechnology at the Royal Institute of Technology (KTH) in 2007, where I later also completed my PhD thesis under the supervision of Harry Brumer, focusing on xyloglucan degradation [1, 2, 3]. After my PhD I worked as a postdoctoral fellow with Phil Pope and Vincent Eijsink at the Norwegian University of Life Sciences (NMBU), mainly on chitin degradation [4]. In 2015 I was appointed Assistant Professor at Chalmers University of Technology, and in 2019 I was promoted to Associate Professor. My research focuses primarily on enzyme (CAZyme) discovery coupled to structural and biochemical characterization.
I have contributed to structure-function studies of CAZymes from various families, including GH5 [2], GH18 [5], GH31 [1, 2, 6], GH35 [3], and CE15 [7, 8, 9, 10, 11].
Selected papers
Error fetching PMID 25171165:
Error fetching PMID 27933102:
Error fetching PMID 30083226:
Error fetching PMID 30814248:
Error fetching PMID 31740581:
Error fetching PMID 32792608:
Error fetching PMID 35304453:
- Larsbrink J, Izumi A, Ibatullin FM, Nakhai A, Gilbert HJ, Davies GJ, and Brumer H. (2011). Structural and enzymatic characterization of a glycoside hydrolase family 31 α-xylosidase from Cellvibrio japonicus involved in xyloglucan saccharification. Biochem J. 2011;436(3):567-80. DOI:10.1042/BJ20110299 |
- Error fetching PMID 24463512:
- Error fetching PMID 25171165:
- Error fetching PMID 27933102:
- Error fetching PMID 32792608:
- Larsbrink J, Izumi A, Hemsworth GR, Davies GJ, and Brumer H. (2012). Structural enzymology of Cellvibrio japonicus Agd31B protein reveals α-transglucosylase activity in glycoside hydrolase family 31. J Biol Chem. 2012;287(52):43288-99. DOI:10.1074/jbc.M112.416511 |
- Error fetching PMID 30083226:
- Error fetching PMID 30814248:
- Error fetching PMID 31740581:
- Krska D, Mazurkewich S, Brown HA, Theibich Y, Poulsen JN, Morris AL, Koropatkin NM, Lo Leggio L, and Larsbrink J. (2021). Structural and Functional Analysis of a Multimodular Hyperthermostable Xylanase-Glucuronoyl Esterase from Caldicellulosiruptor kristjansonii. Biochemistry. 2021;60(27):2206-2220. DOI:10.1021/acs.biochem.1c00305 |
- Error fetching PMID 35304453: