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User:Plinio Vieira

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Plinio Salmazo Vieira obtained his B.Sc. Lic. in Chemistry from the University of São Paulo (2010) and his Ph.D. (2016) at the University of Campinas under the supervision of Mario Murakami and Priscila Oliveira de Giuseppe. During his post-doc at Brazilian National Center for Research in Energy and Materials under the supervision of Dr. Murakami, he studied Glycoside Hydrolases from Xanthomonas that act on Xyloglucan depolymerization. He also worked on a post-doc project under the supervision of Miguel Alcalde at Institute of Catalysis and Petrochemistry, focusing on the engineering and evolution of a GH35 β-galactosidase. He currently works as Researcher Specialist at Brazilian Biorenewables Laboratory, focusing on the discovery and the structure-function-mechanism relationship from CAZymes. He has contributed for the tridimensional structure determination and biochemical characterization of:


  1. Vieira PS, Bonfim IM, Araujo EA, Melo RR, Lima AR, Fessel MR, Paixão DAA, Persinoti GF, Rocco SA, Lima TB, Pirolla RAS, Morais MAB, Correa JBL, Zanphorlin LM, Diogo JA, Lima EA, Grandis A, Buckeridge MS, Gozzo FC, Benedetti CE, Polikarpov I, Giuseppe PO, and Murakami MT. (2021). Xyloglucan processing machinery in Xanthomonas pathogens and its role in the transcriptional activation of virulence factors. Nat Commun. 2021;12(1):4049. DOI:10.1038/s41467-021-24277-4 | PubMed ID:34193873 [Vieira2021]
  2. de Sousa, A.S., de Melo, R.R., Miyamoto, R.Y., Morais, M.A.B., Andrade, L.P., Milan, N., de Avila, M.C., de Souza, C.M., Adão, R.C., Scarpassa, J.A., Vieira, P.S., dos Santos, L.V., Ramos, C.H.I., Murakami, M.T. and Zanphorlin, L.M. (2020). A rationally identified marine GH1 β-glucosidase has distinguishing functional features for simultaneous saccharification and fermentation. Biofuels, Bioprod. Bioref. 2020;14(6):1163-1179. DOI: 10.1002/bbb.2136

    [Sousa2020]
  3. Domingues MN, Souza FHM, Vieira PS, de Morais MAB, Zanphorlin LM, Dos Santos CR, Pirolla RAS, Honorato RV, de Oliveira PSL, Gozzo FC, and Murakami MT. (2018). Structural basis of exo-β-mannanase activity in the GH2 family. J Biol Chem. 2018;293(35):13636-13649. DOI:10.1074/jbc.RA118.002374 | PubMed ID:29997257 [Domingues2018]
  4. de Melo RR, de Lima EA, Persinoti GF, Vieira PS, de Sousa AS, Zanphorlin LM, de Giuseppe PO, Ruller R, and Murakami MT. (2021). Identification of a cold-adapted and metal-stimulated β-1,4-glucanase with potential use in the extraction of bioactive compounds from plants. Int J Biol Macromol. 2021;166:190-199. DOI:10.1016/j.ijbiomac.2020.10.137 | PubMed ID:33164774 [Melo2021]
  5. Santos CR, Costa PACR, Vieira PS, Gonzalez SET, Correa TLR, Lima EA, Mandelli F, Pirolla RAS, Domingues MN, Cabral L, Martins MP, Cordeiro RL, Junior AT, Souza BP, Prates ÉT, Gozzo FC, Persinoti GF, Skaf MS, and Murakami MT. (2020). Structural insights into β-1,3-glucan cleavage by a glycoside hydrolase family. Nat Chem Biol. 2020;16(8):920-929. DOI:10.1038/s41589-020-0554-5 | PubMed ID:32451508 [Santos2020]

All Medline abstracts: PubMed