CAZypedia celebrates the life of Senior Curator Emeritus Harry Gilbert, a true giant in the field, who passed away in September 2025.


CAZypedia needs your help!

We have many unassigned pages in need of Authors and Responsible Curators. See a page that's out-of-date and just needs a touch-up? - You are also welcome to become a CAZypedian. Here's how.
Scientists at all career stages, including students, are welcome to contribute.
Learn more about CAZypedia's misson here and in this article. Totally new to the CAZy classification? Read this first.

Difference between revisions of "Template:News"

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'''11 October 2017:''' ''Ten years of CAZypedia:'' We are proud to announce the publication of a [https://academic.oup.com/glycob/article-lookup/doi/10.1093/glycob/cwx089 new article in ''Glycobiology''] in celebration of ''CAZypedia's'' tenth anniversary online. This article was written on behalf of all of present and future '''[[:Category:Contributors|Contributors]]''' by Curators [[User:Harry Brumer|Harry Brumer]] and [[User:Spencer Williams|Spencer Williams]], with input from a number of key individuals involved in the genesis of ''CAZypedia'' (''see the [https://academic.oup.com/glycob/article-lookup/doi/10.1093/glycob/cwx089 Acknowledgements section] for full details''). A final post-print version of the manuscript will be [http://hdl.handle.net/2429/63428 freely available]''Thanks to the hard work of a multitude of [[:Category:Contributors|Contributors]], ''CAZypedia'' is a successful example of community-driven, expert-based biocuration. We look forward to the continued development of this resource over the next ten years!''
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'''23 January 2026:''' ''An oldie, but a goodie:'' As our first page of the new year, the '''[[Glycoside Hydrolase Family 71]]''' page, written by '''[[User:Antonielle Vieira Monclaro|Antonielle Vieira Monclaro]]''', was [[Curator Approved]] by '''[[User:Johan Larsbrink|Johan Larsbrink]]''' today.  '''[[GH71]]''' is a family of mostly fungal alpha-1,3-glucanases that was established and subjected to mechanistic characterization in the early 2000s.  More recently in 2025, the Yano and [[User:Johan Larsbrink|Larsbrink]] groups independently presented the first crystal structures of '''[[GH71]]''' members (from ''Schizosaccharomyces'' and ''Aspergillus'', respectively). ''[[User:Antonielle Vieira Monclaro|Antonielle]] wrote an excellent overview of '''[[GH71]]''', which you should definitely check out '''[[GH71|here]]'''.''
 
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'''10 September 2017:''' ''Sussing-out starch recognition in CBM58:'' We are excited to report that '''[[User:Nicole Koropatkin|Nicole Koropatkin]]''' has completed the '''[[Carbohydrate Binding Module Family 58]]''' page today.  [[CBM58]] constitutes a comparatively small family of CBMs found in bacteria in the phylum Bacteroidetes, including key members of the human gut microbiota such as ''Bacteroides thetaiotaomicron''.  Within these bacteria, [[CBM58]] modules are found inserted within the [[GH13]] catalytic module of SusG, the essential outer-membrane-bound amylase of the starch utilization system (sus).  [[User:Nicole Koropatkin|Nicole’s]] seminal structural biology has defined the family and provided insight into the recognition of amylose helices by [[CBM58]] members in SusG homologs. ''Read more about this fascinating system [[Carbohydrate Binding Module Family 58|here]].''    
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'''8 December 2025:''' ''Just in time for the holidays:'' The '''[[Glycosyltransferase Family 138]]''' page by [[Author]] '''[[User:Wei Peng|Wei Peng]]''' and [[Responsible Curator]] '''[[User:Kim Orth|Kim Orth]]''' was [[Curator Approved]] today. '''[[GT138]]''' is small family of plant-associated bacterial members.  The archetype from ''Pseudomonas syringae'', AvrB, is a rhamnosyl transferase that glycosylates the plant host protein RIN4 to effect programmed cell death (hypersensitive response)Also notable, AvrB has an unusual protein fold among [[glycosyltransferases]], based upon a "Fido" domain. '''''[[GT138]]''' represents one of a small, but hopefully growing, number of [[Glycosyltransferases|GT]] pages in ''CAZypedia'', whose unique features you should read more about '''[[GT138|here]]'''.''
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'''31 October 2025:''' ''A spooktacular addition to the CAZypedia family!'' Come and say 'Boo!' to the frighteningly well written '''[[CBM13]]''' ''CAZypedia'' page.  The '''[[CBM13]]''' family is a '''[[Carbohydrate-binding_modules#Blurred Lines: CBMs, Lectins and Outliers|lectin-like CBM family]]'''. Its first characterized members were lectins, including the B chain from the highly toxic [https://en.wikipedia.org/wiki/Ricin ricin] toxin from ''Ricinus communis''.  This spine tingling read was authored by '''[[User:Scott Mazurkewich|Scott Mazurkewich]]''' and '''[[User:Lauren McKee|Lauren McKee]]''' who also acted as responsible curator. ''Come and visit the scariest of ''CAZypedia'' CBM pages, '''[[CBM13|here!]]'''...  if you dare...'' 
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'''29 July 2025:'''  ''[[CBM91]] is in the news!''  The xylan binding '''[[CBM91]]''' family ''CAZypedia'' page is up and runningAppended to mainly [[GH43]] xylanases this [[CBM91]] family drives interaction with substrate. The [[CBM91]] page was authored by '''[[User:Daichi Ito|Daichi Ito]]''' who also discovered the initial xylan-binding function which resulted in the creation of the [[CBM91]] CAZy family. ''Read up on this industrially interesting '''[[CBM91]]''' family '''[[CBM91|here]]'''.''
 
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Latest revision as of 07:14, 26 January 2026

23 January 2026: An oldie, but a goodie: As our first page of the new year, the Glycoside Hydrolase Family 71 page, written by Antonielle Vieira Monclaro, was Curator Approved by Johan Larsbrink today. GH71 is a family of mostly fungal alpha-1,3-glucanases that was established and subjected to mechanistic characterization in the early 2000s. More recently in 2025, the Yano and Larsbrink groups independently presented the first crystal structures of GH71 members (from Schizosaccharomyces and Aspergillus, respectively). Antonielle wrote an excellent overview of GH71, which you should definitely check out here.


8 December 2025: Just in time for the holidays: The Glycosyltransferase Family 138 page by Author Wei Peng and Responsible Curator Kim Orth was Curator Approved today. GT138 is small family of plant-associated bacterial members. The archetype from Pseudomonas syringae, AvrB, is a rhamnosyl transferase that glycosylates the plant host protein RIN4 to effect programmed cell death (hypersensitive response). Also notable, AvrB has an unusual protein fold among glycosyltransferases, based upon a "Fido" domain. GT138 represents one of a small, but hopefully growing, number of GT pages in CAZypedia, whose unique features you should read more about here.


31 October 2025: A spooktacular addition to the CAZypedia family! Come and say 'Boo!' to the frighteningly well written CBM13 CAZypedia page. The CBM13 family is a lectin-like CBM family. Its first characterized members were lectins, including the B chain from the highly toxic ricin toxin from Ricinus communis. This spine tingling read was authored by Scott Mazurkewich and Lauren McKee who also acted as responsible curator. Come and visit the scariest of CAZypedia CBM pages, here!... if you dare...


29 July 2025: CBM91 is in the news! The xylan binding CBM91 family CAZypedia page is up and running. Appended to mainly GH43 xylanases this CBM91 family drives interaction with substrate. The CBM91 page was authored by Daichi Ito who also discovered the initial xylan-binding function which resulted in the creation of the CBM91 CAZy family. Read up on this industrially interesting CBM91 family here.