CAZypedia celebrates the life of Senior Curator Emeritus Harry Gilbert, a true giant in the field, who passed away in September 2025.


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We have many unassigned pages in need of Authors and Responsible Curators. See a page that's out-of-date and just needs a touch-up? - You are also welcome to become a CAZypedian. Here's how.
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Difference between revisions of "Template:News"

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'''13 October 2010:''' '''[[User:Gideon Davies|Gideon Davies]]''' has just completed and approved the '''[[Glycoside Hydrolase Family 18]]''' chitinase/endo-β-''N''-acetylglucosaminidase page, with help from '''[[User:Nathalie Juge|Nathalie Juge]]''' on the non-catalytic proteins in the family, which function as carbohydrate-binding proteins or enzyme inhibitors.  ''Look out for links to this and several of the pages mentioned in previous News items in the latest version of the [http://www.cazy.org/ CAZy database], to be released today!''
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'''23 January 2026:''' ''An oldie, but a goodie:'' As our first page of the new year, the '''[[Glycoside Hydrolase Family 71]]''' page, written by '''[[User:Antonielle Vieira Monclaro|Antonielle Vieira Monclaro]]''', was [[Curator Approved]] by '''[[User:Johan Larsbrink|Johan Larsbrink]]''' today.  '''[[GH71]]''' is a family of mostly fungal alpha-1,3-glucanases that was established and subjected to mechanistic characterization in the early 2000s.  More recently in 2025, the Yano and [[User:Johan Larsbrink|Larsbrink]] groups independently presented the first crystal structures of '''[[GH71]]''' members (from ''Schizosaccharomyces'' and ''Aspergillus'', respectively).  ''[[User:Antonielle Vieira Monclaro|Antonielle]] wrote an excellent overview of '''[[GH71]]''', which you should definitely check out '''[[GH71|here]]'''.''
 
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'''08 October 2010:''' ''Trehalases!:'' ''CAZypedia'' [[Author]] '''[[User:Tracey Gloster|Tracey Gloster]]''' completed the '''[[Glycoside Hydrolase Family 37]]''' page today, which was summarily approved by [[Responsible Curator]] '''[[User:Gideon Davies|Gideon Davies]]'''.  '''[[GH37]]''' is a trehalase-specific family; trehalases are also currently found in [[GH15]] and [[GH65]].
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'''8 December 2025:''' ''Just in time for the holidays:'' The '''[[Glycosyltransferase Family 138]]''' page by [[Author]] '''[[User:Wei Peng|Wei Peng]]''' and [[Responsible Curator]] '''[[User:Kim Orth|Kim Orth]]''' was [[Curator Approved]] today. '''[[GT138]]''' is small family of plant-associated bacterial members.  The archetype from ''Pseudomonas syringae'', AvrB, is a rhamnosyl transferase that glycosylates the plant host protein RIN4 to effect programmed cell death (hypersensitive response)Also notable, AvrB has an unusual protein fold among [[glycosyltransferases]], based upon a "Fido" domain. '''''[[GT138]]''' represents one of a small, but hopefully growing, number of [[Glycosyltransferases|GT]] pages in ''CAZypedia'', whose unique features you should read more about '''[[GT138|here]]'''.''
 
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'''06 October 2010:''' ''A [http://en.wikipedia.org/wiki/Hat-trick hat-trick]:'' '''[[Glycoside Hydrolase Family 5]]''' makes three [[Curator Approved]] family pages by '''[[User:Gideon Davies|Gideon Davies]]''' in one day. '''[[GH5]]''' is a large, poly-specific family, which makes covering the entire scope of this family challenging.  ''CAZypedia'' is an evolving resource, so readers are welcome to suggest further improvements.
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'''31 October 2025:''' ''A spooktacular addition to the CAZypedia family!'' Come and say 'Boo!' to the frighteningly well written '''[[CBM13]]''' ''CAZypedia'' page.  The '''[[CBM13]]''' family is a '''[[Carbohydrate-binding_modules#Blurred Lines: CBMs, Lectins and Outliers|lectin-like CBM family]]'''. Its first characterized members were lectins, including the B chain from the highly toxic [https://en.wikipedia.org/wiki/Ricin ricin] toxin from ''Ricinus communis''.  This spine tingling read was authored by '''[[User:Scott Mazurkewich|Scott Mazurkewich]]''' and '''[[User:Lauren McKee|Lauren McKee]]''' who also acted as responsible curator. ''Come and visit the scariest of ''CAZypedia'' CBM pages, '''[[CBM13|here!]]'''..if you dare...''
 
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'''06 October 2010:''' ''More cellulases - the second family from [[User:Gideon Davies|Gideon]] in one day:''  The '''[[Glycoside Hydrolase Family 45]]''' page has been completed and [[Curator Approved|approved]] by [[Board of Curators|Senior Curator]] '''[[User:Gideon Davies|Gideon Davies]]'''.  '''[[GH45]]''' contains ''endo''-β(1-4)glucanases (''endo''-cellulases), and a significant structural similarity to [http://en.wikipedia.org/wiki/Expansin plant expansins] has been observed.
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'''29 July 2025:''' ''[[CBM91]] is in the news!''  The xylan binding '''[[CBM91]]''' family ''CAZypedia'' page is up and runningAppended to mainly [[GH43]] xylanases this [[CBM91]] family drives interaction with substrate. The [[CBM91]] page was authored by '''[[User:Daichi Ito|Daichi Ito]]''' who also discovered the initial xylan-binding function which resulted in the creation of the [[CBM91]] CAZy family. ''Read up on this industrially interesting '''[[CBM91]]''' family '''[[CBM91|here]]'''.''
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'''06 October 2010:''' ''<u>Yet another</u> classic cellulase family:'' The '''[[Glycoside Hydrolase Family 6]]''' page by '''[[User:Kathleen Piens|Kathleen Piens]]''' and '''[[User:Gideon Davies|Gideon Davies]]''' has just been upgraded to  [[Curator Approved]] status'''[[GH6]]''' contains cellobiohydrolase II (CBHII, or Cel6A in the modern nomenclature), which is a main component of the enzyme cocktail secreted by the proficient cellulose-degrading organism, ''Hypocrea jecorica'' (''née Trichoderma reesei'').
 
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'''24 August 2010:''' ''Another classic cellulase family:'' '''[[User:David Wilson|David Wilson]]''' and '''[[User:Breeanna Urbanowicz|Breeanna Urbanowicz]]''' have teamed-up to produce the '''[[Glycoside Hydrolase Family 9]]''' page, which has been upgraded to [[Curator Approved]] status today.  '''[[GH9]]''' is a family of [[inverting]] ''endo''-beta(1-4)glucanases with a long history, including important structure/function work from '''[[User:David Wilson|David's lab]]'''.  '''[[User:Breeanna Urbanowicz|Bree]]''' has written a '''[[Glycoside Hydrolase Family 9/Plant endoglucanases|special addendum on the structure, function, and phylogeny of the plant endoglucanases]]''', which have been implicated in cell wall biosynthesis.
 
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'''11 August 2010:''' ''A new look.'' Today we upgraded the [http://www.mediawiki.org/ MediaWiki] software that runs ''CAZypedia'' and switched the default interface to the shiny new [http://en.wikipedia.org/wiki/Wikipedia:Vector Vector skin], which you may have already noticed on [http://www.wikipedia.org/ Wikipedia].  Let us know if you find any problems with the new layout [[Special:Contact|here]]. <small>''(If preferred, CAZypedians can actually still use the old default skin, Monobook, by logging in and changing their user preferences.)''</small>
 
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'''10 August 2010:''' ''A bit of extra polishing:'' [[Responsible Curator|Curator]] and [[Author]] '''[[User:Harry Gilbert|Harry Gilbert]]''' has now touched-up and further improved the '''[[Glycoside Hydrolase Family 43]]''' &alpha;-L-arabinofuranosidase/&beta;-D-xylosidase page, which was [[Curator Approved]] back in November 2009.
 
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'''22 July 2010:''' ''Number 60!''  Today ''CAZypedia'' chalks-up its 60th [[Curator Approved]] [[Glycoside Hydrolase Families|Glycoside Hydrolase Family]] family page, '''[[Glycoside Hydrolase Family 116|GH116]]''' by [[Author]] '''[[User:Beatrice Cobucci-Ponzano|Beatrice Cobucci-Ponzano]]''' and [[Responsible Curator]] '''[[User: Marco Moracci| Marco Moracci]]'''.  '''[[Glycoside Hydrolase Family 116|GH116]]''' is a brand-new beta-glycosidase family, which was created after a seminal publication by the Neapolitan group in ''The Journal of Biological Chemistry'' '''very''' recently (in print July 2...check the '''[[GH116]]''' page for more details!).
 
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'''8 July 2010:''' ''CAZypedia breaks new ground:''  ''CAZypedia'' has made its first foray into the world of glycosyltransferases with the '''[[Glycosyltransferase Family 42|GT42 page]]''' by '''[[User:Warren Wakarchuk|Warren Wakarchuk]]'''.  The [[Glycosyltransferase Families]] are still very much in a beta test stage, and we welcome input and ideas on the format of these pages.
 
 
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Latest revision as of 07:14, 26 January 2026

23 January 2026: An oldie, but a goodie: As our first page of the new year, the Glycoside Hydrolase Family 71 page, written by Antonielle Vieira Monclaro, was Curator Approved by Johan Larsbrink today. GH71 is a family of mostly fungal alpha-1,3-glucanases that was established and subjected to mechanistic characterization in the early 2000s. More recently in 2025, the Yano and Larsbrink groups independently presented the first crystal structures of GH71 members (from Schizosaccharomyces and Aspergillus, respectively). Antonielle wrote an excellent overview of GH71, which you should definitely check out here.


8 December 2025: Just in time for the holidays: The Glycosyltransferase Family 138 page by Author Wei Peng and Responsible Curator Kim Orth was Curator Approved today. GT138 is small family of plant-associated bacterial members. The archetype from Pseudomonas syringae, AvrB, is a rhamnosyl transferase that glycosylates the plant host protein RIN4 to effect programmed cell death (hypersensitive response). Also notable, AvrB has an unusual protein fold among glycosyltransferases, based upon a "Fido" domain. GT138 represents one of a small, but hopefully growing, number of GT pages in CAZypedia, whose unique features you should read more about here.


31 October 2025: A spooktacular addition to the CAZypedia family! Come and say 'Boo!' to the frighteningly well written CBM13 CAZypedia page. The CBM13 family is a lectin-like CBM family. Its first characterized members were lectins, including the B chain from the highly toxic ricin toxin from Ricinus communis. This spine tingling read was authored by Scott Mazurkewich and Lauren McKee who also acted as responsible curator. Come and visit the scariest of CAZypedia CBM pages, here!... if you dare...


29 July 2025: CBM91 is in the news! The xylan binding CBM91 family CAZypedia page is up and running. Appended to mainly GH43 xylanases this CBM91 family drives interaction with substrate. The CBM91 page was authored by Daichi Ito who also discovered the initial xylan-binding function which resulted in the creation of the CBM91 CAZy family. Read up on this industrially interesting CBM91 family here.