CAZypedia celebrates the life of Senior Curator Emeritus Harry Gilbert, a true giant in the field, who passed away in September 2025.


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Difference between revisions of "Template:News"

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'''4 February 2019:''' ''CAZypedia's first CE page!''  Today [[Responsible Curator]] '''[[User:Michael Suits|Michael Suits]]''' approved the '''[[Carbohydrate Esterase Family 4]]''' page [[author]]ed by graduate student '''[[User:Alex Anderson|Alex Anderson]]''', thereby marking a new milestone ''CAZypedia's'' [[CAZypedia:History|history]].  [[:Category:Carbohydrate Esterase Families|Carbohydrate Esterases (CEs)]] catalyze the de-''O''-acylation or de-''N''-acylation of saccharides (the latter are formally amidases), and '''[[CE4]]''' contains members with either activity, ''e.g.'' acetylxylan esterases and peptidoglycan deacetylases. '''[[CE4]]''' members thus play diverse biological roles in nature.  ''Learn more about the structure and mechanism of these metal-dependent de-acylases [[CE4|here]]''.
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'''23 January 2026:''''An oldie, but a goodie:'' As our first page of the new year, the '''[[Glycoside Hydrolase Family 71]]''' page, written by '''[[User:Antonielle Vieira Monclaro|Antonielle Vieira Monclaro]]''', was [[Curator Approved]] by '''[[User:Johan Larsbrink|Johan Larsbrink]]''' today.  '''[[GH71]]''' is a family of mostly fungal alpha-1,3-glucanases that was established and subjected to mechanistic characterization in the early 2000sMore recently in 2025, the Yano and [[User:Johan Larsbrink|Larsbrink]] groups independently presented the first crystal structures of '''[[GH71]]''' members (from ''Schizosaccharomyces'' and ''Aspergillus'', respectively). ''[[User:Antonielle Vieira Monclaro|Antonielle]] wrote an excellent overview of '''[[GH71]]''', which you should definitely check out '''[[GH71|here]]'''.''
 
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'''27 November 2018:''' ''Remember, remember... an end of November new CAZypedia CBM family page.'' The type C L-rhamnose binding [[CBM67]] family is now on-line in CAZypedia.  '''[[User:Satoshi Kaneko|Satoshi Kaneko]]''' authored the page and '''[[User:Harry Gilbert|Harry Gilbert]]''' acted as responsible curator.  ''Learn more about the structure and function of the [[CBM67]] family on its CAZypedia [[CBM67|page]]''.
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'''8 December 2025:''' ''Just in time for the holidays:'' The '''[[Glycosyltransferase Family 138]]''' page by [[Author]] '''[[User:Wei Peng|Wei Peng]]''' and [[Responsible Curator]] '''[[User:Kim Orth|Kim Orth]]''' was [[Curator Approved]] today. '''[[GT138]]''' is small family of plant-associated bacterial membersThe archetype from ''Pseudomonas syringae'', AvrB, is a rhamnosyl transferase that glycosylates the plant host protein RIN4 to effect programmed cell death (hypersensitive response).  Also notable, AvrB has an unusual protein fold among [[glycosyltransferases]], based upon a "Fido" domain. '''''[[GT138]]''' represents one of a small, but hopefully growing, number of [[Glycosyltransferases|GT]] pages in ''CAZypedia'', whose unique features you should read more about '''[[GT138|here]]'''.''
 
 
 
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'''23 November 2018:''' ''Welcome to the CAZypedia fold [[CBM49]]!'' The crystalline cellulose-binding [[CBM49]] CAZypedia page was authored by '''[[User:Breeanna Urbanowicz|Breeanna Urbanowicz]]''' and '''[[User:Elizabeth Ficko-Blean|Elizabeth Ficko-Blean]]''''''[[User:Breeanna Urbanowicz|Breeanna Urbanowicz]]''' also acted as responsible curator.  There is experimental evidence that rice [[CBM49]] is cleaved post-translationally in vivo which probably plays an important role in plant growth. ''Find out more about the functionally interesting family 49 CBMs [[CBM49|here]]''.
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'''31 October 2025:''' ''A spooktacular addition to the CAZypedia family!'' Come and say 'Boo!' to the frighteningly well written '''[[CBM13]]''' ''CAZypedia'' page.  The '''[[CBM13]]''' family is a '''[[Carbohydrate-binding_modules#Blurred Lines: CBMs, Lectins and Outliers|lectin-like CBM family]]'''. Its first characterized members were lectins, including the B chain from the highly toxic [https://en.wikipedia.org/wiki/Ricin ricin] toxin from ''Ricinus communis''.  This spine tingling read was authored by '''[[User:Scott Mazurkewich|Scott Mazurkewich]]''' and '''[[User:Lauren McKee|Lauren McKee]]''' who also acted as responsible curator. ''Come and visit the scariest of ''CAZypedia'' CBM pages, '''[[CBM13|here!]]'''...  if you dare...'' 
 
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'''11 October 2018:''' ''Fall ushers in a new CAZypedia CBM family page.''  The chitin-binding and lytic polysaccharide monooxygenase associated [[CBM73]] family is described in detail. '''[[User:Zarah Forsberg|Zarah Forsberg]]''' authored the page and '''[[User:Gustav Vaaje-Kolstad|Gustav Vaaje-Kolstad]]''' acted as responsible curator. ''Learn more about the [[CBM73]] family on its CAZypedia [[CBM73|page]]''.
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'''29 July 2025:''' ''[[CBM91]] is in the news!'' The xylan binding '''[[CBM91]]''' family ''CAZypedia'' page is up and running. Appended to mainly [[GH43]] xylanases this [[CBM91]] family drives interaction with substrate. The [[CBM91]] page was authored by '''[[User:Daichi Ito|Daichi Ito]]''' who also discovered the initial xylan-binding function which resulted in the creation of the [[CBM91]] CAZy family. ''Read up on this industrially interesting '''[[CBM91]]''' family '''[[CBM91|here]]'''.''
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'''24 September 2018:''' ''Revenge of the Ruminococci Part Deux.'' Two more CBM families from Ruminococcal bacteria are ready for reading. The [[CBM79]] and [[CBM80]] CAZypedia pages were authored by '''[[User:Immacolata Venditto|Immacolata Venditto]]''' and '''[[User:Harry Gilbert|Harry Gilbert]]''' acted as responsible curator. These CBMs are important for enzyme targeting but also for targeting the entire cellulosome complex to substrate. ''More information on the [[CBM79]] and [[CBM80]] families can be found on their respective CAZypedia pages.''
 
 
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Latest revision as of 07:14, 26 January 2026

23 January 2026: An oldie, but a goodie: As our first page of the new year, the Glycoside Hydrolase Family 71 page, written by Antonielle Vieira Monclaro, was Curator Approved by Johan Larsbrink today. GH71 is a family of mostly fungal alpha-1,3-glucanases that was established and subjected to mechanistic characterization in the early 2000s. More recently in 2025, the Yano and Larsbrink groups independently presented the first crystal structures of GH71 members (from Schizosaccharomyces and Aspergillus, respectively). Antonielle wrote an excellent overview of GH71, which you should definitely check out here.


8 December 2025: Just in time for the holidays: The Glycosyltransferase Family 138 page by Author Wei Peng and Responsible Curator Kim Orth was Curator Approved today. GT138 is small family of plant-associated bacterial members. The archetype from Pseudomonas syringae, AvrB, is a rhamnosyl transferase that glycosylates the plant host protein RIN4 to effect programmed cell death (hypersensitive response). Also notable, AvrB has an unusual protein fold among glycosyltransferases, based upon a "Fido" domain. GT138 represents one of a small, but hopefully growing, number of GT pages in CAZypedia, whose unique features you should read more about here.


31 October 2025: A spooktacular addition to the CAZypedia family! Come and say 'Boo!' to the frighteningly well written CBM13 CAZypedia page. The CBM13 family is a lectin-like CBM family. Its first characterized members were lectins, including the B chain from the highly toxic ricin toxin from Ricinus communis. This spine tingling read was authored by Scott Mazurkewich and Lauren McKee who also acted as responsible curator. Come and visit the scariest of CAZypedia CBM pages, here!... if you dare...


29 July 2025: CBM91 is in the news! The xylan binding CBM91 family CAZypedia page is up and running. Appended to mainly GH43 xylanases this CBM91 family drives interaction with substrate. The CBM91 page was authored by Daichi Ito who also discovered the initial xylan-binding function which resulted in the creation of the CBM91 CAZy family. Read up on this industrially interesting CBM91 family here.