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Difference between revisions of "User:Plinio Vieira"
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| − | Plinio Salmazo Vieira obtained his B.Sc. Lic. in Chemistry from the University of São Paulo (2010) and his Ph.D. (2016) at the University of Campinas under the supervision of [[User:Mario Murakami|Mario Murakami]] and [[User:Priscila Giuseppe|Priscila Oliveira de Giuseppe]]. The work focused on the crystallographic studies of NEK kinases from Trypanosomatids, aiming for structural-based drug design. During his post-doc at [https://cnpem.br/ Brazilian National Center for Research in Energy and Materials] under the supervision of Dr. Murakami, he studied Glycoside Hydrolases from ''Xanthomonas'' that act on Xyloglucan depolymerization. He also worked on a post-doc project under the supervision of [https://miguelalcaldelab.eu/contact/ Miguel Alcalde] at [https://icp.csic.es/ Institute of Catalysis and Petrochemistry], focusing on the random and semi-rational evolution of a GH35 β-galactosidase. He currently works as Researcher Specialist at [https://lnbr.cnpem.br Brazilian Biorenewables Laboratory], focusing on the discovery and the structure-function | + | Plinio Salmazo Vieira obtained his B.Sc. Lic. in Chemistry from the University of São Paulo (2010) and his Ph.D. (2016) at the University of Campinas under the supervision of [[User:Mario Murakami|Mario Murakami]] and [[User:Priscila Giuseppe|Priscila Oliveira de Giuseppe]]. The work focused on the crystallographic studies of NEK kinases from Trypanosomatids, aiming for structural-based drug design. During his post-doc at [https://cnpem.br/ Brazilian National Center for Research in Energy and Materials] under the supervision of Dr. Murakami, he studied Glycoside Hydrolases from ''Xanthomonas'' that act on Xyloglucan depolymerization. He also worked on a post-doc project under the supervision of [https://miguelalcaldelab.eu/contact/ Miguel Alcalde] at [https://icp.csic.es/ Institute of Catalysis and Petrochemistry], focusing on the random and semi-rational evolution of a GH35 β-galactosidase. He currently works as Researcher Specialist at [https://lnbr.cnpem.br Brazilian Biorenewables Laboratory], focusing on the discovery and the structure-function relationship from CAZymes. He has contributed for the tridimensional structure determination and biochemical characterization of: |
| − | *[[CE20]] '''Family first''' ''Xac''XaeA [https://www.rcsb.org/structure/7KMM | + | *[[CE20]] '''Family first''' ''Xac''XaeA [https://www.rcsb.org/structure/7KMM 7KMM] <cite>Vieira2021</cite> |
| − | *[[GH2]] ''Xac''Man2A [https://www.rcsb.org/structure/6BYC | + | *[[GH2]] ''Xac''Man2A [https://www.rcsb.org/structure/6BYC 6BYC] [https://www.rcsb.org/structure/6BYE 6BYE] [https://www.rcsb.org/structure/6BYI ID 6BYI][https://www.rcsb.org/structure/6BYG 6BYG] <cite>Domingues2018</cite> |
| − | *[[GH31]] ''Xac''Xyl31 [https://www.rcsb.org/structure/7KMP | + | |
| − | *[[GH35]] ''Xac''GalD [https://www.rcsb.org/structure/7KMN | + | *[[GH3]] ''Xac''Xyl3A, ''Xac''Xyl3B, ''Xac''Bgl3A, ''Xac''Bgl3B, ''Xac''Bgl3C <cite>Vieira2021</cite> |
| − | *[[GH74]] ''Xcc''Xeg74 [https://www.rcsb.org/structure/7KN8 | + | |
| − | *[[GH95]] ''Xac''Afc95 [https://www.rcsb.org/structure/7KMQ | + | *[[GH31]] ''Xac''Xyl31 [https://www.rcsb.org/structure/7KMP 7KMP] [https://www.rcsb.org/structure/7KNC 7KNC] <cite>Vieira2021</cite> |
| − | *[[GH128]] AmGH128_I [https://www.rcsb.org/structure/6UAU | + | |
| − | *[[GH128]] ScGH128_II [https://www.rcsb.org/structure/6UAX/ | + | *[[GH35]] ''Xac''GalD [https://www.rcsb.org/structure/7KMN 7KMN] [https://www.rcsb.org/structure/7KMO 7KMO] <cite>Vieira2021</cite> |
| − | *[[GH128]] LeGH128_IV [https://www.rcsb.org/structure/6UB2 | + | *[[GH74]] ''Xcc''Xeg74 [https://www.rcsb.org/structure/7KN8 7KN8] <cite>Vieira2021</cite> |
| − | *[[GH128]] AnGH128_VI [https://www.rcsb.org/structure/6UB8 | + | *[[GH95]] ''Xac''Afc95 [https://www.rcsb.org/structure/7KMQ 7KMQ] <cite>Vieira2021</cite> |
| − | *[[GH128]] CnGH128_VII [https://www.rcsb.org/structure/6UBC | + | *[[GH128]] AmGH128_I [https://www.rcsb.org/structure/6UAU 6UAU] [https://www.rcsb.org/structure/6UAT 6UAT] [https://www.rcsb.org/structure/6UFZ 6UBFZ] [https://www.rcsb.org/structure/6UAS/ PDB ID 6UAS] [https://www.rcsb.org/structure/6UFL PDB ID 6UFL] <cite>Santos2020</cite> |
| + | *[[GH128]] ScGH128_II [https://www.rcsb.org/structure/6UAX/ 6UAX] <cite>Santos2020</cite> | ||
| + | *[[GH128]] LeGH128_IV [https://www.rcsb.org/structure/6UB2 6UB2] <cite>Santos2020</cite> | ||
| + | *[[GH128]] AnGH128_VI [https://www.rcsb.org/structure/6UB8 6UB8] [https://www.rcsb.org/structure/6UBA 6UAB] [https://www.rcsb.org/structure/6UBB 6UBB] <cite>Santos2020</cite> | ||
| + | *[[GH128]] CnGH128_VII [https://www.rcsb.org/structure/6UBC 6UBC] <cite>Santos2020</cite> | ||
---- | ---- | ||
Revision as of 08:40, 22 March 2023
Plinio Salmazo Vieira obtained his B.Sc. Lic. in Chemistry from the University of São Paulo (2010) and his Ph.D. (2016) at the University of Campinas under the supervision of Mario Murakami and Priscila Oliveira de Giuseppe. The work focused on the crystallographic studies of NEK kinases from Trypanosomatids, aiming for structural-based drug design. During his post-doc at Brazilian National Center for Research in Energy and Materials under the supervision of Dr. Murakami, he studied Glycoside Hydrolases from Xanthomonas that act on Xyloglucan depolymerization. He also worked on a post-doc project under the supervision of Miguel Alcalde at Institute of Catalysis and Petrochemistry, focusing on the random and semi-rational evolution of a GH35 β-galactosidase. He currently works as Researcher Specialist at Brazilian Biorenewables Laboratory, focusing on the discovery and the structure-function relationship from CAZymes. He has contributed for the tridimensional structure determination and biochemical characterization of:
- GH35 XacGalD 7KMN 7KMO [1]
- GH74 XccXeg74 7KN8 [1]
- GH95 XacAfc95 7KMQ [1]
- GH128 AmGH128_I 6UAU 6UAT 6UBFZ PDB ID 6UAS PDB ID 6UFL [3]
- GH128 ScGH128_II 6UAX [3]
- GH128 LeGH128_IV 6UB2 [3]
- GH128 AnGH128_VI 6UB8 6UAB 6UBB [3]
- GH128 CnGH128_VII 6UBC [3]
- Vieira PS, Bonfim IM, Araujo EA, Melo RR, Lima AR, Fessel MR, Paixão DAA, Persinoti GF, Rocco SA, Lima TB, Pirolla RAS, Morais MAB, Correa JBL, Zanphorlin LM, Diogo JA, Lima EA, Grandis A, Buckeridge MS, Gozzo FC, Benedetti CE, Polikarpov I, Giuseppe PO, and Murakami MT. (2021). Xyloglucan processing machinery in Xanthomonas pathogens and its role in the transcriptional activation of virulence factors. Nat Commun. 2021;12(1):4049. DOI:10.1038/s41467-021-24277-4 |
- Domingues MN, Souza FHM, Vieira PS, de Morais MAB, Zanphorlin LM, Dos Santos CR, Pirolla RAS, Honorato RV, de Oliveira PSL, Gozzo FC, and Murakami MT. (2018). Structural basis of exo-β-mannanase activity in the GH2 family. J Biol Chem. 2018;293(35):13636-13649. DOI:10.1074/jbc.RA118.002374 |
- Santos CR, Costa PACR, Vieira PS, Gonzalez SET, Correa TLR, Lima EA, Mandelli F, Pirolla RAS, Domingues MN, Cabral L, Martins MP, Cordeiro RL, Junior AT, Souza BP, Prates ÉT, Gozzo FC, Persinoti GF, Skaf MS, and Murakami MT. (2020). Structural insights into β-1,3-glucan cleavage by a glycoside hydrolase family. Nat Chem Biol. 2020;16(8):920-929. DOI:10.1038/s41589-020-0554-5 |