CAZypedia needs your help! We have many unassigned GH, PL, CE, AA, GT, and CBM pages in need of Authors and Responsible Curators.
Scientists at all career stages, including students, are welcome to contribute to CAZypedia. Read more here, and in the 10th anniversary article in Glycobiology.
New to the CAZy classification? Read this first.
Consider attending the 15th Carbohydrate Bioengineering Meeting in Ghent, 5-8 May 2023.
I completed in 2012 my PhD studies focused on engineering glycoside hydrolases (GHs) into transglycosylases, particularly GH1  and GH36 , under the supervision of professors Michel Dion and Vinh Tran.
After a few years working in a different field (radiochemistry and theoretical chemistry), I came back to the CAZymes world thanks to a postdoctoral position mentored by professor Birte Svensson (in Lyngby, close to Copenhagen, Denmark). I continued to work on engineering GHs, to turn them into transglycosylases as well as phosphorylases  and efficient glycosynthases. I also got more involved in completing glycoside hydrolases mechanisms, especially GH84  and GH109, and started to work on glycosyltransferases.
- Teze D, Hendrickx J, Czjzek M, Ropartz D, Sanejouand YH, Tran V, Tellier C, and Dion M. (2014). Semi-rational approach for converting a GH1 β-glycosidase into a β-transglycosidase. Protein Eng Des Sel. 2014;27(1):13-9. DOI:10.1093/protein/gzt057 |
- Teze D, Daligault F, Ferrières V, Sanejouand YH, and Tellier C. (2015). Semi-rational approach for converting a GH36 α-glycosidase into an α-transglycosidase. Glycobiology. 2015;25(4):420-7. DOI:10.1093/glycob/cwu124 |
- Teze D, Coines J, Raich L, Kalichuk V, Solleux C, Tellier C, André-Miral C, Svensson B, and Rovira C. (2020). A Single Point Mutation Converts GH84 O-GlcNAc Hydrolases into Phosphorylases: Experimental and Theoretical Evidence. J Am Chem Soc. 2020;142(5):2120-2124. DOI:10.1021/jacs.9b09655 |