CAZypedia needs your input! We have many unassigned GH, PL, CE, AA, GT, and CBM pages in need of Authors and Responsible Curators.
Scientists at all career stages, including students, are welcome to contribute to CAZypedia. Read more here, and in the 10th anniversary article in Glycobiology.
New to the CAZy classification? Read this first.
The entries listed below comprise a lexicon of key terms and concepts in CAZypedia. Specifically, the aim of the lexicon is to provide a precise definition of various specialized terms unique to carbohydrate chemistry [1, 2, 3], as well as a general overview of the catalytic mechanisms of the major carbohydrate-active enzyme (CAZyme) classes [4, 5, 6, 7, 8].
These pages have been approved by the Responsible Curator as essentially complete. CAZypedia is a living document, so further improvement of these pages is still possible; please see the individual pages for more information.
There are currently 24 Curator approved Lexicon pages in CAZypedia.
- Absolute configuration (D/L nomenclature)
- Alpha-glucan lyases
- Anomeric centre (alpha and beta)
- Carbohydrate Bioengineering Meetings
- Carbohydrate-active enzymes
- Carbohydrate-binding modules
- Catalytic nucleophile
- Conformational itinerary
- Conformational nomenclature
- General acid/base
- Glycoside hydrolases
- Oxazolinium ion
- Oxocarbenium ion
- Polysaccharide epimerases
- Reaction intermediate
- Sequence-based classification
- Sub-site nomenclature
- Surface Binding Site
- Syn/anti lateral protonation
- Transition state
These pages are currently under construction in CAZypedia. As such, the Responsible Curator has deemed that the page's content is not quite up to CAZypedia's standards for full public consumption. All information on these pages should therefore be considered to be under revision and may be subject to major changes.
There are currently 1 Lexicon pages under construction in CAZypedia.
- Robert V. Stick and Spencer J. Williams. (2009) Carbohydrates. Elsevier Science.
- Michael Sinnott. (2007) Carbohydrate Chemistry and Biochemistry. Royal Society of Chemistry.
- P. M. Collins and Robert J. Ferrier. (1995) Monosaccharides. John Wiley & Sons.
Sinnott, M.L. (1990) Catalytic mechanisms of enzymic glycosyl transfer. Chem. Rev. 90, 1171-1202. DOI: 10.1021/cr00105a006
- McCarter JD and Withers SG. (1994). Mechanisms of enzymatic glycoside hydrolysis. Curr Opin Struct Biol. 1994;4(6):885-92. DOI:10.1016/0959-440x(94)90271-2 |
- Yip VL and Withers SG. (2006). Breakdown of oligosaccharides by the process of elimination. Curr Opin Chem Biol. 2006;10(2):147-55. DOI:10.1016/j.cbpa.2006.02.005 |
- Vocadlo DJ and Davies GJ. (2008). Mechanistic insights into glycosidase chemistry. Curr Opin Chem Biol. 2008;12(5):539-55. DOI:10.1016/j.cbpa.2008.05.010 |
- Lairson LL, Henrissat B, Davies GJ, and Withers SG. (2008). Glycosyltransferases: structures, functions, and mechanisms. Annu Rev Biochem. 2008;77:521-55. DOI:10.1146/annurev.biochem.76.061005.092322 |