CAZypedia needs your help! We have many unassigned GH, PL, CE, AA, GT, and CBM pages in need of Authors and Responsible Curators.
Scientists at all career stages, including students, are welcome to contribute to CAZypedia. Read more here, and in the 10th anniversary article in Glycobiology.
New to the CAZy classification? Read this first.
*
Consider attending the 15th Carbohydrate Bioengineering Meeting in Ghent, 5-8 May 2024.

Difference between revisions of "Template:News"

From CAZypedia
Jump to navigation Jump to search
m
 
(343 intermediate revisions by 3 users not shown)
Line 1: Line 1:
−
'''7 January 2015:''' ''Love your guts:'' ''CAZypedia'' is ringing in the new year with a new '''[[Glycoside Hydrolase Family 76]]''' page by '''[[User:Spencer Williams|Spencer Williams]]'''.  '''[[GH76]]''' contains endo-acting α-mannanases, including members from the human gut bacterium ''Bacteroides thetaiotaomicron'' that enable us to degrade yeast mannans in our diet.  A very recent publication in ''Nature'', notably involving ''CAZypedia'' contributors '''[[User:Michael Suits|Michael Suits]]''', '''[[User:Al Boraston|Al Boraston]]''', '''[[User:Spencer Williams|Spencer Williams]]''', '''[[User:Gideon Davies|Gideon Davies]]''', '''[[User:Wade Abbott|Wade Abbott]]''', and '''[[User:Harry Gilbert|Harry Gilbert]]''', has recently shed new light on the structure, mechanism, and biological function of these enzymes.  ''Read more [[Glycoside Hydrolase Family 76|here]]!''
+
'''2 May 2024:''' ''CBDs I to X... A major milestone!'' '''CBM families 1 to 10 are now complete!''' These are the old CBD (cellulose-binding domain) families, which used to have roman numerals as part of their nomenclature. A special thank you to all the authors and responsible curators who have contributed to this major milestone. Go have a peek at each of these old school families on their respective ''CAZypedia'' pages: '''[[CBM1]], [[CBM2]], [[CBM3]], [[CBM4]], [[CBM5]], [[CBM6]], [[CBM7]], [[CBM8]], [[CBM9]], and [[CBM10]]'''.
 
----
 
----
−
'''11 September 2014:''' ''Another PL family done:'' Today, '''[[User:Richard McLean|Richard McLean]]''' and '''[[User:Wade Abbott|Wade Abbott]]''' finished the '''[[Polysaccharide Lyase Family 22]]''' page, bringing the number of [[Curator Approved]] [[PL]] pages in ''CAZypedia'' to a total of 5 (of 23).  '''[[PL22]]''' is a family of bacterial (and a handful of archeal) oligogalacturonide lyases (OGLs), archetypal members of which are highly specific for digalacturonate and Δ4,5-unsaturated digalacturonate ''i.e.'', they do not cleave polymeric α-(1,4)-linked galacturonan, a component of pectin. [[User:Wade Abbott|Wade]] performed a seminal crystallographic analysis of [[PL22]], and he and [[User:Richard McLean|Richard]] have produced a lucid distillation of the mechanism of catalysis in this family.  ''Read more [[Polysaccharide Lyase Family 22|here]]!''
+
'''11 February 2024:''' ''A "BLAST" from the past, with a fresh update.'' [[Author]] '''[[User:Eduardo Moreno Prieto|Eduardo Moreno Prieto]]''' composed a new page on '''[[Glycoside Hydrolase Family 119]]''',a family of bacterial amylases, which was [[Curator Approved]] by '''[[User:Stefan Janecek|Stefan Janecek]]''' and '''[[User:Bernard Henrissat|Bernard Henrissat]]''' today.  The first member of '''[[GH119]]''' was characterized in 2006, and through sequence analysis with [[GH57]] members, [[User:Stefan Janecek|Janeček]] and Kuchtová predicted the active-site residues in 2012.  Over a decade later, '''[[User:Eduardo Moreno Prieto|Eduardo]]''', '''[[User:Bernard Henrissat|Bernard]]''', and colleagues finally provided critical experimental support for these predictions.  ''Learn more about this history, and especially the relationship between '''[[GH119]]''' and '''[[GH57]]''', in CAZypedia.''
 
----
 
----
−
'''9 September 2014:''' ''2-for-1 Back to School Special:'' With the start of the new academic year, we are happy to report that two new [[Polysaccharide Lyase Families|Polysaccharide Lyase Family]] pages have recently been completed and given [[Curator Approved]] status.  In August, '''[[User:Naotake Konno|Naotake Konno]]''' and '''[[User:Shinya Fushinobu|Shinya Fushinobu]]''' produced the '''[[Polysaccharide Lyase Family 20]]''' page, which describes this small (currently, 18 member) group of bacterial and fungal beta-(1-4)-glucuronan-cleaving enzymes. ''And'', on the 7th of this month, '''[[User:Sine Larsen|Sine Larsen]]''' and '''[[User:Leila LoLeggio|Leila LoLeggio]]''' composed the '''[[Polysaccharide Lyase Family 4]]''' page. Currently, '''[[PL4]]''' is only known to contain rhamnogalacturonan lyases involved in pectin degradation, notably including many plant sequences in addition to bacterial and fungal members.  We thank these [[Author]]s and [[Responsible Curator]]s for their contributions and encourage our readers to check out these new pages.
+
'''3 February 2024:''' ''A new family of beta-1,2-glucan-cyclizing enzymes.'' A page on the (currently) newest GH family, '''[[Glycoside Hydrolase Family 189]]''', was completed today by [[Author]]s '''[[User:Tomoko Masaike|Tomoko Masaike]]''', '''[[User:Masahiro Nakajima|Masahiro Nakajima]]''', and '''[[User:Nobukiyo Tanaka|Nobukiyo Tanaka]]''' ([[User:Masahiro Nakajima|Masahiro Nakajima]] is the [[Responsible Curator]]). '''[[GH189]]''' is a family of bacterial transglycosylases that comprise a critical domain in cyclic beta-1,2-glucan synthase (CGS), because this domain is responsible for the final cyclization step during the biosynthesis of these key effector molecules.  The discovery of '''[[GH189]]''' builds on similarly exciting work by these authors and their colleagues on beta-1,2-glucan hydrolases in [[GH144]] and [[GH162]], which share a common protein fold with '''[[GH189]]''', but have distinct mechansims. ''Check out the '''[[GH189]]''', [[GH144]], and [[GH162]] pages to learn more about this breakthrough work on beta-1,2-glucan-active enzymes!''
−
----
 
−
'''2 July 2014:''' ''More on the alpha-amylase clan:'' We are pleased to report that '''[[User:Stefan Janecek|Stefan Janecek]]''' has made another key contribution to ''CAZypedia'' by completing the '''[[Glycoside Hydrolase Family 77]]''' page today.  '''[[GH77]]''' contains enzymes variously known as ''amylomaltases'', ''4-α-glucanotransferases'', or ''disproportionating enzymes'' (''D-enzymes'' in plants), which catalyze (1-4)-to-(1-4) transglycosylation of alpha-glucan chains and form part of the starch/glycogen debranching system.  Together with [[GH13]] and [[GH70]], [[GH77]] constitutes [[Clan]] GH-H, a clan of alpha-glucan-specific enzymes united by a common (β/α)<sub>8</sub> catalytic domain fold.  [[User:Stefan Janecek|Stefan]] is the founder and main organiser of ''ALAMY'' - the international symposia on the alpha-amylase enzyme family -  and has been a key person in producing the [[GH13]], [[GH70]], [[GH77]] pages in ''CAZypedia''; we are especially grateful for all his hard work and expertise!
 
−
----
 
−
'''23 June 2014:'''
 
−
''"LysM" domains in CAZypedia:'' The cohort of [[Carbohydrate Binding Module Families]] covered in ''CAZypedia'' continues to grow with the completion of the '''[[Carbohydrate Binding Module Family 50]]''' by '''[[User:Takayuki Ohnuma|Takayuki Ohnuma]]''' and '''[[User:Toki Taira|Toki Taira]]'''.  [[CBM50]] members are also known as LysM domains, which are found in a range of enzymes beyond glycoside hydrolases, including proteases, in which they are believed to facilitate targeting and degradation the bacterial cell wall. ''Read more [[Carbohydrate Binding Module Family 50|here...!]]''
 
 
----
 
----

Latest revision as of 08:08, 2 May 2024

2 May 2024: CBDs I to X... A major milestone! CBM families 1 to 10 are now complete! These are the old CBD (cellulose-binding domain) families, which used to have roman numerals as part of their nomenclature. A special thank you to all the authors and responsible curators who have contributed to this major milestone. Go have a peek at each of these old school families on their respective CAZypedia pages: CBM1, CBM2, CBM3, CBM4, CBM5, CBM6, CBM7, CBM8, CBM9, and CBM10.

11 February 2024: A "BLAST" from the past, with a fresh update. Author Eduardo Moreno Prieto composed a new page on Glycoside Hydrolase Family 119,a family of bacterial amylases, which was Curator Approved by Stefan Janecek and Bernard Henrissat today. The first member of GH119 was characterized in 2006, and through sequence analysis with GH57 members, Janeček and Kuchtová predicted the active-site residues in 2012. Over a decade later, Eduardo, Bernard, and colleagues finally provided critical experimental support for these predictions. Learn more about this history, and especially the relationship between GH119 and GH57, in CAZypedia.

3 February 2024: A new family of beta-1,2-glucan-cyclizing enzymes. A page on the (currently) newest GH family, Glycoside Hydrolase Family 189, was completed today by Authors Tomoko Masaike, Masahiro Nakajima, and Nobukiyo Tanaka (Masahiro Nakajima is the Responsible Curator). GH189 is a family of bacterial transglycosylases that comprise a critical domain in cyclic beta-1,2-glucan synthase (CGS), because this domain is responsible for the final cyclization step during the biosynthesis of these key effector molecules. The discovery of GH189 builds on similarly exciting work by these authors and their colleagues on beta-1,2-glucan hydrolases in GH144 and GH162, which share a common protein fold with GH189, but have distinct mechansims. Check out the GH189, GH144, and GH162 pages to learn more about this breakthrough work on beta-1,2-glucan-active enzymes!

Retrieved from "http://www.cazypedia.org/index.php?title=Template:News&oldid=18023"