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Difference between revisions of "User:Birgitte Zeuner"
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== Background == | == Background == | ||
| − | I obtained an MSc degree in Biotechnology at [https://www.kt.dtu.dk Department of Chemical and Biochemical Engineering], [https://www.dtu.dk Technical University of Denmark] in 2009. I continued my PhD studies there under the supervision of Anne S. Meyer, where I worked with [[CE1]] feruloyl esterases to catalyze transesterification in ionic liquids <cite>Zeuner2011 Zeuner2012</cite>, as well as with [[GH33]] sialidases for transsialylation <cite>Zeuner2014a Zeuner2014b</cite>. Starting from solvent engineering and reaction design to improve enzyme-catalysed synthesis, my work has since evolved to include protein engineering and enzyme discovery. My post doc studies included a lot of carbohydrate analysis (HPAEC-PAD) and work on [[GH33]] sialidases <cite>Zeuner2016a Nordvang2016 Zeuner2017</cite>, [[GH29]] α-L-fucosidases <cite>Zeuner2018a Zeuner2018b | + | I obtained an MSc degree in Biotechnology at [https://www.kt.dtu.dk Department of Chemical and Biochemical Engineering], [https://www.dtu.dk Technical University of Denmark] in 2009. I continued my PhD studies there under the supervision of Anne S. Meyer, where I worked with [[CE1]] feruloyl esterases to catalyze transesterification in ionic liquids <cite>Zeuner2011 Zeuner2012</cite>, as well as with [[GH33]] sialidases for transsialylation <cite>Zeuner2014a Zeuner2014b</cite>. Starting from solvent engineering and reaction design to improve enzyme-catalysed synthesis, my work has since evolved to include protein engineering and enzyme discovery. My post doc studies included a lot of carbohydrate analysis (HPAEC-PAD) and work on [[GH33]] sialidases <cite>Zeuner2016a Nordvang2016 Zeuner2017</cite>, [[GH29]] α-L-fucosidases <cite>Zeuner2018a Zeuner2018b Zeuner2020a Zeuner2020c</cite>, [[GH20]] β-''N''-acetylhexosaminidases <cite>Nyffenegger2015 Jamek2018</cite>, and other GH families <cite>Zeuner2016b</cite> for transglycosylation to yield human milk oligosaccharide structures. In 2018, I was appointed Assistant Professor in Enzyme Technology for Oligosaccharide Synthesis at [https://www.bioengineering.dtu.dk/english Department of Biotechnology and Biomedicine], [https://www.dtu.dk Technical University of Denmark]. My current work focuses on transglycosylation <cite>Zeuner2014c, Zeuner2019, Muschiol2020, Zeuner2020a, Zeuner2020c</cite>. As GH-catalysed synthesis is not always a walk in the park, I sometimes spend time off from that to deal with targeted carbohydrate breakdown using [[PL1]] pectin lyases <cite>Chung2017 Zeuner2020b</cite>. |
== Selected papers == | == Selected papers == | ||
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<biblio> | <biblio> | ||
| − | #Zeuner2011 Zeuner B, Ståhlberg T, van Buu ON, Kunov-Kruse AJ, Riisager A, Meyer AS (2011) Dependency of the hydrogen bonding capacity of the solvent anion on the thermal stability of feruloyl esterases in ionic liquid systems. Green Chem. 13, 1550-1557.[https://doi.org/10.1039/C1GC15115K DOI: 10.1039/C1GC15115K] | + | #Zeuner2011 Zeuner B, Ståhlberg T, van Buu ON, Kunov-Kruse AJ, Riisager A, Meyer AS (2011) Dependency of the hydrogen bonding capacity of the solvent anion on the thermal stability of feruloyl esterases in ionic liquid systems. Green Chem. 13, 1550-1557. [https://doi.org/10.1039/C1GC15115K DOI: 10.1039/C1GC15115K] |
#Zeuner2012 pmid=22154740 | #Zeuner2012 pmid=22154740 | ||
#Zeuner2014a pmid=24411449 | #Zeuner2014a pmid=24411449 | ||
| Line 17: | Line 17: | ||
#Zeuner2016a pmid=26672447 | #Zeuner2016a pmid=26672447 | ||
#Nordvang2016 pmid=27367145 | #Nordvang2016 pmid=27367145 | ||
| − | #Zeuner2017 Zeuner B, González-Delgado I, Holck J, Morales G, López-Muñoz MJ, Segura Y, Meyer AS, Mikkelsen JD (2017) Characterization and immobilization of engineered sialidases from Trypanosoma rangeli for transsialylation. AIMS Mol. Sci. 4(2), 140-163.[https://doi.org/10.3934/molsci.2017.2.140 DOI: 10.3934/molsci.2017.2.140] | + | #Zeuner2017 Zeuner B, González-Delgado I, Holck J, Morales G, López-Muñoz MJ, Segura Y, Meyer AS, Mikkelsen JD (2017) Characterization and immobilization of engineered sialidases from Trypanosoma rangeli for transsialylation. AIMS Mol. Sci. 4(2), 140-163. [https://doi.org/10.3934/molsci.2017.2.140 DOI: 10.3934/molsci.2017.2.140] |
| − | #Muschiol2020 Muschiol J, Vuillemin M, Meyer AS, Zeuner B. (2020) β-N-Acetylhexosaminidases for carbohydrate synthesis via trans-glycosylation. Catalysts 10, 365.[https://doi.org/10.3390/catal10040365 DOI: 10.3390/catal10040365] | + | #Muschiol2020 Muschiol J, Vuillemin M, Meyer AS, Zeuner B. (2020) β-N-Acetylhexosaminidases for carbohydrate synthesis via trans-glycosylation. Catalysts 10, 365. [https://doi.org/10.3390/catal10040365 DOI: 10.3390/catal10040365] |
#Jamek2018 pmid=29911342 | #Jamek2018 pmid=29911342 | ||
#Nyffenegger2015 pmid=25843303 | #Nyffenegger2015 pmid=25843303 | ||
#Zeuner2019 pmid=31141914 | #Zeuner2019 pmid=31141914 | ||
#Zeuner2014c pmid=25208138 | #Zeuner2014c pmid=25208138 | ||
| − | |||
#Zeuner2018a pmid=29221760 | #Zeuner2018a pmid=29221760 | ||
#Zeuner2018b pmid=29859601 | #Zeuner2018b pmid=29859601 | ||
| − | + | #Zeuner2020a pmid=32445980 | |
| − | # | ||
| − | |||
#Chung2017 pmid=29029078 | #Chung2017 pmid=29029078 | ||
| − | |||
#Zeuner2016b pmid=26802542 | #Zeuner2016b pmid=26802542 | ||
| − | + | #Zeuner2020b pmid=32850731 | |
| + | #Zeuner2020c pmid=33217923 | ||
| + | #Teze2020 pmid=33914359 | ||
</biblio> | </biblio> | ||
<!-- Do not remove this Category tag --> | <!-- Do not remove this Category tag --> | ||
[[Category:Contributors|Zeuner,Birgitte]] | [[Category:Contributors|Zeuner,Birgitte]] | ||
Latest revision as of 03:43, 14 February 2022
Assistant Professor at the Department of Biotechnology and Biomedicine, Technical University of Denmark. My ORCID is here and my contact details are here.
Background
I obtained an MSc degree in Biotechnology at Department of Chemical and Biochemical Engineering, Technical University of Denmark in 2009. I continued my PhD studies there under the supervision of Anne S. Meyer, where I worked with CE1 feruloyl esterases to catalyze transesterification in ionic liquids [1, 2], as well as with GH33 sialidases for transsialylation [3, 4]. Starting from solvent engineering and reaction design to improve enzyme-catalysed synthesis, my work has since evolved to include protein engineering and enzyme discovery. My post doc studies included a lot of carbohydrate analysis (HPAEC-PAD) and work on GH33 sialidases [5, 6, 7], GH29 α-L-fucosidases [8, 9, 10, 11], GH20 β-N-acetylhexosaminidases [12, 13], and other GH families [14] for transglycosylation to yield human milk oligosaccharide structures. In 2018, I was appointed Assistant Professor in Enzyme Technology for Oligosaccharide Synthesis at Department of Biotechnology and Biomedicine, Technical University of Denmark. My current work focuses on transglycosylation [10, 11, 15, 16, 17]. As GH-catalysed synthesis is not always a walk in the park, I sometimes spend time off from that to deal with targeted carbohydrate breakdown using PL1 pectin lyases [18, 19].
Selected papers
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Zeuner B, Ståhlberg T, van Buu ON, Kunov-Kruse AJ, Riisager A, Meyer AS (2011) Dependency of the hydrogen bonding capacity of the solvent anion on the thermal stability of feruloyl esterases in ionic liquid systems. Green Chem. 13, 1550-1557. DOI: 10.1039/C1GC15115K
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- Error fetching PMID 24411449:
- Error fetching PMID 24563319:
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Zeuner B, González-Delgado I, Holck J, Morales G, López-Muñoz MJ, Segura Y, Meyer AS, Mikkelsen JD (2017) Characterization and immobilization of engineered sialidases from Trypanosoma rangeli for transsialylation. AIMS Mol. Sci. 4(2), 140-163. DOI: 10.3934/molsci.2017.2.140
- Error fetching PMID 29221760:
- Error fetching PMID 29859601:
- Error fetching PMID 32445980:
- Error fetching PMID 33217923:
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- Error fetching PMID 29911342:
- Error fetching PMID 26802542:
- Error fetching PMID 25208138:
- Error fetching PMID 31141914:
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Muschiol J, Vuillemin M, Meyer AS, Zeuner B. (2020) β-N-Acetylhexosaminidases for carbohydrate synthesis via trans-glycosylation. Catalysts 10, 365. DOI: 10.3390/catal10040365
- Error fetching PMID 29029078:
- Error fetching PMID 32850731:
- Error fetching PMID 33914359: