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User:Magali Remaud-Simeon

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Magali Remaud-Siméon graduated from the National Institute of Applied Science of Toulouse in 1985 and received her PhD in 1988. Then she was as Post-Doctotal Fellow at the University of Pensylvania where she worked with Prof D. Graves in the department of Chemical and Biomolecular Engineering. From 1990 to 2000, she was an associate professor at the Institute of Technology of the University of Toulouse in the department of Applied Biology. Since 2001, she is a professor at the National Institute of Applied Science of Toulouse. As the head of the Enzyme Molecular Engineering and Catalysis group since 2001, she focuses her research activities on enzyme engineering for white biotechnology, green chemistry, Food/Feed industries and synthetic biology. Her areas of interest cover enzyme structure/activity relationship studies, kinetic resolution, evolution combining both rational and combinatorial approaches, and applications to the synthesis of new polysaccharides, oligosaccharides, glycoonjugates, esters and enantiopure compounds. She has been working on glucansucrases from GH family 70 and 13 since 1985. With her collaborators, she has elucidated the mechanism of dextran, alternan and amylose biosynthesis by dextransucrase, alternansucrase and amylosucrase, respectively. Her work is currently focused on the search and generation of enzymes displaying new specificities and improved properties towards unnatural substrate.