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Difference between revisions of "User:Yann Mathieu"
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Latest revision as of 11:13, 14 October 2021
Yann Mathieu obtained his MsC in Protein Engineering in 2009 from the Université de Lorraine and completed his PhD in 2012 under the supervision of Eric Gelhaye and Marc Buée at the Université de Lorraine in the Tree-Microbe Interactions research unit. This work looked at the ecological and functional diversity of wood decomposing fungi and how the substrate influences their communities, their secreted biomass degrading enzymes [1] and their detoxification enzymes [2] with a focus on glutathione S-transferases and their structure-function relationship [3, 4].
He then moved to the south of France in Marseille to work as a post-doctoral scientist, in the Fungal Biodiversity and Biotechnology Laboratory, studying fungal oxidoreductases such as GMC-oxidoreductases AA3 [5, 6, 7] and lytic polysaccharide monooxygenases AA9 and their role in biomass degradation [8].
After 2 years in Marseille, he moved to Vancouver at the University of British Columbia in Vancouver to pursue his work on fungal oxidoreductases within Harry Brumer's group where his research focuses on the screening, production, characterisation and structure-function relationship of lytic polysaccharide monooxygenases AA9 [9] and copper radical oxidases AA5_2 to better understand their substrate scope [10], physiological roles and their applications in biocatalysis [11].
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Mathieu, Y., Offen, W. A., Forget, S. M., Ciano, L., Viborg, A. H., Blagova, E., Henrissat, B., Walton, P.H, Davies, G.J, and Brumer, H. (2020). Discovery of a fungal copper radical oxidase with high catalytic efficiency toward 5-hydroxymethylfurfural and benzyl alcohols for bioprocessing. ACS Catalysis, 10(5), 3042-3058. https://pubs.acs.org/doi/abs/10.1021/acscatal.9b04727