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Glycoside Hydrolase Family 61
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GH61 is a deleted family
The enzymes in this family were originally classified as a glycoside hydrolases (GH61) based on very weak endo-1,4-beta-D-glucanase activity in one family member. They are now reclassified into Auxiliary Activity Family 9 in CAZy . AA9 proteins are copper-dependent lytic polysaccharide monooxygenases (LPMOs); cleavage of cellulose chains with oxidation of various carbons (C-1, C-4 and C-6) has been reported several times in the literature (see  and references therein).
- Levasseur A, Drula E, Lombard V, Coutinho PM, and Henrissat B. (2013) Expansion of the enzymatic repertoire of the CAZy database to integrate auxiliary redox enzymes. Biotechnol Biofuels. 6, 41. DOI:10.1186/1754-6834-6-41 |
- Hemsworth GR, Davies GJ, and Walton PH. (2013) Recent insights into copper-containing lytic polysaccharide mono-oxygenases. Curr Opin Struct Biol. 23, 660-8. DOI:10.1016/j.sbi.2013.05.006 |
|CAZy DB links|