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Difference between revisions of "User:Yaoguang Chang"
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| − | [[ | + | [[File:Yaoguang Chang.jpg|100px|right]] |
| − | + | Yaoguang Chang obtained his Ph.D. degree from the Ocean University of China and was a visiting scholar at the University of Massachusetts Amherst. At present, he is a professor at the College of Food Science and Engineering, Ocean University of China. His research interests involve the gene-mining and characterization of [[Carbohydrate-active enzymes|CAZymes]] and [[carbohydrate-binding modules]] from marine polysaccharides. By utilizing the enzymes and binding proteins as critical tools, novel identification, quantification, and modification methods of marine polysaccharides were established, which would consequently facilitate the development and application of promising functional polysaccharides from the ocean. | |
| + | His research group discovered the first member of [[GH168]], [[GH174]], and [[CBM92]] families, and contributed to the studies related to members of the following families: | ||
| − | + | *[[GH16]]: κ-carrageenase Cgk16A <cite>Shen2018</cite>, βκ-carrageenase Cgbk16A_Wf <cite>Cao2021</cite>, β-porphyranase Por16A_Wf <cite>Zhang2019</cite>, and β-porphyranase Por16C_Wf <cite>Zhang2020</cite> | |
| − | + | *[[GH29]]: fucosidase Alf1_Wf <cite>Dong2017</cite> | |
| − | * | + | *[[GH82]]: ι-carrageenase Cgi82A <cite>Shen2017</cite> |
| − | * | + | *[[GH86]]: β-agarase Aga86A_Wa <cite>Cao2020 Zhang2023</cite> |
| − | * | + | *[[GH168]]: endo-1,3-fucanase Fun168A <cite>Shen2020</cite> |
| − | + | *[[GH174]]: endo-1,3-fucanase Fun174A <cite>Liu2023</cite> | |
| − | + | *[[PL7]]: alginate lyase Aly7B_Wf <cite>Pei2019</cite> | |
| + | *[[CBM16]]: ABP_Wf (alginate-binding CBM) <cite>Mei2020</cite> | ||
| + | *[[CBM47]]: WfCBM47 (sulfated fucan-binding CBM) <cite>Mei2020a</cite> | ||
| + | *[[CBM70]]: SrCBM70 (hyaluronic acid-binding CBM) <cite>Mei2020b</cite> | ||
| + | *[[CBM92]]: Cgk16A-CBM92 (carrageenan-binding CBM) <cite>Mei2020c</cite> | ||
| + | *CBMnc: Fun174A-CBM (sulfated fucan-binding CBM) <cite>Mei2023</cite> | ||
| + | Some of the above biotechnological tools have been successfully integrated with glycomics <cite>Chen2021 Chen2023</cite>, lateral flow immunoassay <cite>Mei2020b</cite>, and other techniques, and served in the structural and chemical investigation of marine polysaccharides. And some enzymes have been employed to produce low molecular weight polysaccharides and oligosaccharides with verified bioactivities <cite>Cheng2022 Li2021</cite>. | ||
| + | == References == | ||
| + | <biblio> | ||
| + | #Shen2018 pmid=29355636 | ||
| + | #Cao2021 pmid=34421852 | ||
| + | #Zhang2019 pmid=31352784 | ||
| + | #Zhang2020 pmid=32520542 | ||
| + | #Dong2017 pmid=27576198 | ||
| + | #Shen2017 pmid=28760444 | ||
| + | #Cao2020 pmid=32578425 | ||
| + | #Zhang2023 pmid=36746585 | ||
| + | #Shen2020 pmid=32849348 | ||
| + | #Liu2023 pmid=36746582 | ||
| + | #Pei2019 pmid=30248453 | ||
| + | #Mei2020 pmid=32747278 | ||
| + | #Mei2022a pmid=34893209 | ||
| + | #Mei2022b pmid=36395930 | ||
| + | #Mei2022c pmid=35830544 | ||
| + | #Mei2023 pmid=36924869 | ||
| + | #Chen2021 pmid=34420739 | ||
| + | #Chen2023 pmid=37059545 | ||
| + | #Cheng2022 pmid=35667104 | ||
| + | #Li2021 pmid=34415766 | ||
| + | </biblio> | ||
| − | |||
| − | |||
| − | |||
| − | |||
<!-- Do not remove this Category tag --> | <!-- Do not remove this Category tag --> | ||
[[Category:Contributors|Chang,Yaoguang]] | [[Category:Contributors|Chang,Yaoguang]] | ||
Latest revision as of 09:24, 20 April 2023
Yaoguang Chang obtained his Ph.D. degree from the Ocean University of China and was a visiting scholar at the University of Massachusetts Amherst. At present, he is a professor at the College of Food Science and Engineering, Ocean University of China. His research interests involve the gene-mining and characterization of CAZymes and carbohydrate-binding modules from marine polysaccharides. By utilizing the enzymes and binding proteins as critical tools, novel identification, quantification, and modification methods of marine polysaccharides were established, which would consequently facilitate the development and application of promising functional polysaccharides from the ocean. His research group discovered the first member of GH168, GH174, and CBM92 families, and contributed to the studies related to members of the following families:
- GH16: κ-carrageenase Cgk16A [1], βκ-carrageenase Cgbk16A_Wf [2], β-porphyranase Por16A_Wf [3], and β-porphyranase Por16C_Wf [4]
- GH29: fucosidase Alf1_Wf [5]
- GH82: ι-carrageenase Cgi82A [6]
- GH86: β-agarase Aga86A_Wa [7, 8]
- GH168: endo-1,3-fucanase Fun168A [9]
- GH174: endo-1,3-fucanase Fun174A [10]
- PL7: alginate lyase Aly7B_Wf [11]
- CBM16: ABP_Wf (alginate-binding CBM) [12]
- CBM47: WfCBM47 (sulfated fucan-binding CBM) [13]
- CBM70: SrCBM70 (hyaluronic acid-binding CBM) [14]
- CBM92: Cgk16A-CBM92 (carrageenan-binding CBM) [15]
- CBMnc: Fun174A-CBM (sulfated fucan-binding CBM) [16]
Some of the above biotechnological tools have been successfully integrated with glycomics [17, 18], lateral flow immunoassay [14], and other techniques, and served in the structural and chemical investigation of marine polysaccharides. And some enzymes have been employed to produce low molecular weight polysaccharides and oligosaccharides with verified bioactivities [19, 20].
References
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