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- === Creation of the new GH162 and GH189 families (Family first) === ...f GH enzymes. This leads to the classification of the TfSGL group as a new GH family, [[GH162]] <cite>Tanaka2019</cite>.2 KB (313 words) - 09:27, 26 February 2024
- ** Glycoside_Hydrolase_Families|GH Families ** Polysaccharide_Lyase_Families|PL Families1 KB (131 words) - 08:34, 14 June 2019
- ...of the GH families by following this link: [[:Category:Glycoside Hydrolase Families]]''' ''(TIP: Right click with your mouse and open the link in a new browser |GH-x3 KB (401 words) - 12:27, 4 July 2023
- ...ite>Cantarel2009 Lombard2013</cite>). Each of the resulting sequence-based families contain proteins that are related by sequence, and by corollary, three-dime === Families ===6 KB (768 words) - 14:20, 18 December 2021
- |GH-A |inferred from clan [http://www.cazy.org/Glycoside-Hydrolases.html GH-A]<br>as two Glu3 KB (370 words) - 14:14, 18 December 2021
- ''This page lists all the Glycoside Hydrolase (GH) Family pages in ''CAZypedia'' that have been given [[:Category:Curator app ...of GHs into families, it has subsequently been observed that some of these families also group non-hydrolytic enzymes and proteins, due to sequence and structu7 KB (908 words) - 14:23, 17 December 2023
- ...of these [[phosphorylases]] with the [[glycoside hydrolases]] of [[clan]] GH-L <cite>Hidaka2004</cite>. The distinction between [[phosphorylases]] rela [[Category:Glycosyltransferase Families|GT036]]1 KB (134 words) - 14:16, 18 December 2021
- |GH-A ...d that this family belongs to the GH-A clan, being remotely related to the families [[GH30]] and [[GH5]] <cite>Cabral2022</cite>.4 KB (469 words) - 15:01, 5 July 2023
- ...nations|Lexicon]] '''·''' [[:Category:Glycoside Hydrolase Families|GH Families]] '''·''' [[:Category:Contributors|Contributors]] ...nations|Lexicon]] '''·''' [[:Category:Glycoside Hydrolase Families|GH Families]] '''·''' [[:Category:Contributors|Contributors]]4 KB (512 words) - 11:02, 24 September 2009
- ...CAZypedians create a consistent layout for [[Glycoside Hydrolase Families|GH]] family entries.''' It can be [http://www.mediawiki.org/wiki/Transclusion |GH-x3 KB (382 words) - 12:26, 4 July 2023
- ...ed classification|classified]] as [[glycoside hydrolases]] into various GH families on the basis of sequence similarity. ===Families===4 KB (506 words) - 09:54, 12 November 2015
- ...een [http://www.cazy.org/ CAZy] [[Carbohydrate Binding Module Families|CBM families]]: [[CBM20]], [[CBM21]], [[CBM25]], [[CBM26]], [[CBM34]], [[CBM41]], [[CBM42 KB (302 words) - 12:23, 12 February 2024
- |GH-I ...ot yet been studied. However, sequence similarity with members of [[Clan]] GH-I suggests that these enzymes may operate with inversion of the anomeric co4 KB (495 words) - 14:15, 18 December 2021
- |GH-x The glycoside hydrolases from GH family 142 have β-L-arabinofuranosidase ([{{EClink}}3.2.1.185 EC 3.2.1.1852 KB (260 words) - 15:12, 25 August 2023
- |none (similar to GH-L) ...ause of the evolutionary, structural and mechanistic relatedness with clan GH-L glycoside hydrolases, the family was re-assigned to family GH94 <cite>Hid4 KB (557 words) - 14:19, 18 December 2021
- ...charide monooxygenases (LPMO), gave impetus to a reclassification of these families into a ...ess to the carbohydrates comprising the plant cell wall. Currently, the AA families contain redox-active enzymes.5 KB (589 words) - 16:01, 13 December 2021
- |GH-A ...o display activity towards β(1,3)-glucans, making this the fourth [[clan]] GH-A [[glycoside hydrolase]] family known to contain β(1,3)-glucanase activit5 KB (605 words) - 14:15, 18 December 2021
- ...ratorApprovedGHPages}} [[Glycoside Hydrolase Families|Glycoside Hydrolase (GH) Family pages]],<br> {{CuratorApprovedPLPages}} [[Polysaccharide Lyase Families|Polysaccharide Lyase (PL) Family pages]],<br>5 KB (651 words) - 10:56, 4 February 2019
- ...[[GH162]]''', '''[[GH186]]''' and '''[[GH189]]''' and also created '''clan GH-S'''. He determined the functions and/or crystal structures of ...al β-1,2-glucanase <cite>Tanaka2019</cite> ('''family created''') ('''clan GH-S created''')3 KB (374 words) - 21:55, 27 April 2024
- |GH-A Hydrophobic cluster analysis showed that BACOVA_05493 is a member of Clan GH-A. Based on this assumption the catalytic nucleophile and general acid/base3 KB (353 words) - 14:15, 18 December 2021
- |GH-A |inferred from clan GH-A as two Glu4 KB (597 words) - 14:14, 18 December 2021
- |GH-x ...what to put in each field from ''Curator Approved'' [[Glycoside Hydrolase Families]]. ''(TIP: Right click with your mouse and open this link in a new browser2 KB (275 words) - 14:17, 18 December 2021
- |GH-x ...what to put in each field from ''Curator Approved'' [[Glycoside Hydrolase Families]]. ''(TIP: Right click with your mouse and open this link in a new browser2 KB (275 words) - 14:16, 18 December 2021
- |GH-x ...2024</cite>. This enzyme established the novel glycoside hydrolase family (GH) 189. This enzyme specifically catalyzes transglycosylation reactions on li6 KB (895 words) - 18:29, 24 February 2024
- ...udies of glycoside hydrolases, with a particular focus on proteins from GH families [[GH3]], [[GH5]], [[GH6]], [[GH7]], [[GH16]] and [[GH61]]. Lately the group3 KB (427 words) - 01:11, 4 March 2010
- |GH-C ...rved. As a historical note, GH11 was one of the first glycoside hydrolase families classified by sequence analysis, and was previously known as "Cellulase Fam3 KB (451 words) - 09:40, 29 July 2015
- |GH-x ...what to put in each field from ''Curator Approved'' [[Glycoside Hydrolase Families]]. ''(TIP: Right click with your mouse and open this link in a new browser2 KB (283 words) - 17:33, 4 January 2023
- |GH-x ...what to put in each field from ''Curator Approved'' [[Glycoside Hydrolase Families]]. ''(TIP: Right click with your mouse and open this link in a new browser2 KB (283 words) - 17:38, 4 January 2023
- * Confusion about sugar ring faces; GH people seem to prefer calling the faces based on the sides relative to the ...ugar ring case as described in that paper (p2440 right column). I like the GH nomenclature because it is intuitive, and Rose et al. suggested a possibili8 KB (1,287 words) - 08:44, 21 August 2018
- |GH-x ...what to put in each field from ''Curator Approved'' [[Glycoside Hydrolase Families]]. ''(TIP: Right click with your mouse and open this link in a new browser2 KB (280 words) - 14:19, 18 December 2021
- ...According to the [http://www.cazy.org/CBM92.html CAZy database], these GH families comprise enzymes with various substrate specificities, including κ-carrage [[Category:Carbohydrate Binding Module Families|CBM092]]4 KB (502 words) - 06:07, 5 May 2024
- |GH-x ...what to put in each field from ''Curator Approved'' [[Glycoside Hydrolase Families]]. ''(TIP: Right click with your mouse and open this link in a new browser2 KB (288 words) - 19:22, 15 December 2023
- |GH-J ...y, and therefore GH families 68 and [[GH32|32]] have been combined in clan GH-J. On the other hand, a structural relationship of the catalytic core exist6 KB (686 words) - 14:14, 18 December 2021
- ...ibuted to this major milestone. Go have a peek at each of these old school families on their respective ''CAZypedia'' pages: '''[[CBM1]], [[CBM2]], [[CBM3]], [ ...y of beta-1,2-glucan-cyclizing enzymes.'' A page on the (currently) newest GH family, '''[[Glycoside Hydrolase Family 189]]''', was completed today by [[2 KB (382 words) - 08:08, 2 May 2024
- .../cite>. Glycoside phosphorylases have been found in a total of 7 GH and GT families (see below). ...-like in their sequence classification. Phosphorolysis of a glycoside by a GH-like phosphorylase with net inversion of anomeric configuration is achieved8 KB (986 words) - 14:20, 18 December 2021
- |GH-R ...ogether with enzymes from the CAZY family [[GH29]], they form the [[clan]] GH-R. Sequences of GH107 family members were first reported in 2006 <cite>Col4 KB (597 words) - 14:19, 18 December 2021
- |GH-D ...echanism]] <cite>Sinnott1990</cite>, like their [[GH27]] relatives in Clan GH-D. This mechanism involves the formation of a covalent glycosyl-enzyme [[i7 KB (891 words) - 14:20, 18 December 2021
- |GH-M ...link}}3.2.1.156 3.2.1.156]). GH8 was one of the first glycoside hydrolase families classified by hydrophobic cluster analysis, and was previously known as "Ce5 KB (653 words) - 14:15, 18 December 2021
- |GH-A ...alysis and sequence alignments to predict that the family belonged to clan GH-A, and the two proposed catalytic residues, which were confirmed by a combi5 KB (602 words) - 14:16, 18 December 2021
- ...uld mean GH140 is a distant relative of Clan GH-A enzymes, however in with GH-A the catalytic residue atop of β-strands 4 and 7 are both glutamates. In [[Category:Glycoside Hydrolase Families|GH140]]3 KB (439 words) - 14:14, 18 December 2021
- ...Zeuner2014c, Zeuner2019, Muschiol2020, Zeuner2020a, Zeuner2020c</cite>. As GH-catalysed synthesis is not always a walk in the park, I sometimes spend tim3 KB (461 words) - 03:43, 14 February 2022
- |GH-N ...Asp396 in Dex49A) are conserved in the catalytic centre of members of clan GH-N, GH49 and [[GH28]] enzymes <cite>Larsson2003 Mizuno2008</cite>, and all t4 KB (567 words) - 20:08, 13 April 2023
- | GH-L ...gnment was provided by structural alignment with other members of [[Clan]] GH-L, specifically [[GH15]] and [[GH65]], which revealed conservation of these5 KB (663 words) - 14:38, 18 December 2021
- |GH-J ...predicted by detailed sequence analysis <cite>10</cite>. All three enzyme families display a five bladed β-propeller fold.5 KB (562 words) - 14:18, 18 December 2021
- |GH-x ...G (monomer).jpg|thumb]]There is no structural homolog of GH186 in whole GH families<cite>MotouchiEc2023</cite> (January 2024). EcOpgG consists of an N-terminal5 KB (637 words) - 02:41, 25 January 2024
- |GH-A ...trimer of dimmers) and each monomer is organized into two domains: a ‘clan GH-A’ catalytic (β/α)<sub>8</sub> domain and a 12-stranded β sandwich wit4 KB (514 words) - 14:18, 18 December 2021
- |GH-A ...l protonation|''anti''-protonation]] of the leaving group, typical of clan GH-A glycoside hydrolases. This residue forms hydrogen bonding interactions wi5 KB (663 words) - 14:19, 18 December 2021
- ...e> and Nam et al. <cite>Nam2009</cite><br> suggest that it belongs to Clan GH-A. ...te> or the [http://expasy.org/cgi-bin/lists?glycosid.txt ExPASy page on GH families].5 KB (732 words) - 14:18, 18 December 2021
- |GH-A ...hydrolases that have similar substrate specificities but are classified in families [[GH16]], [[GH55]], [[GH64]] and [[GH81]].8 KB (1,085 words) - 14:20, 18 December 2021
- ...ity of York, York, UK) where his work focused on glycoside hydrolases from families [[GH26]], [[GH38]], [[GH85]], and [[GH92]], and glycosyltransferase family * GH-Non-Classified ''Streptococcus pyogenes'' plasmin and fibronectin binding p2 KB (237 words) - 14:38, 18 December 2021
- |GH-T In the CAZy database, the two largest amylolytic families, [[GH13]] and [[GH57]], are notably multi-specific, with α-amylase represe9 KB (1,170 words) - 03:06, 26 February 2024
- |GH-A ...a GH128 enzyme <cite>Sakamoto2011</cite>, this family is part of [[Clan]] GH-A, thus suggesting that its members operate by a classical Koshland [[retai9 KB (1,237 words) - 14:14, 18 December 2021
- .... Although similar β-helix structural architectures have been found in the families [[GH28]], [[GH91]], [[PL6]], and [[CE8]], no catalytic activity of the isol ...205462650 GH43] and [https://www.ncbi.nlm.nih.gov/protein/2205462646 GH97] families <cite>Cabral2022</cite>. The [[GH10]] domain is active on arabinoxylan and4 KB (538 words) - 03:21, 6 July 2023
- |GH-K ...d Endo-F3), and both substrates (Endo-M) and belong to glycoside hydrolase families 18 and 85. Although specificity appears to be primarily determined by the o6 KB (734 words) - 14:19, 18 December 2021
- |GH-x [[Category:Glycoside Hydrolase Families|GH083]]2 KB (311 words) - 14:18, 18 December 2021
- |GH-A ...a (β/α)<sub>8</sub> TIM-barrel fold, as found for all members of [[clan]] GH-A.4 KB (515 words) - 14:17, 18 December 2021
- ...''Figure 1. Domain architecture of ''E. rectale'' Amy13K''' The CBM and GH families are indicated. The 'S' is the signal sequence and the 'anchor' is a cell wa [[Category:Carbohydrate Binding Module Families|CBM083]] <!-- ATTENTION: Make sure to replace "nnn" with a three digit fami3 KB (433 words) - 14:20, 18 December 2021
- ...''Figure 1. Domain architecture of ''E. rectale'' Amy13K''' The CBM and GH families are noted. The 'S' indicate the signal sequence and the 'anchor' is a cell [[Category:Carbohydrate Binding Module Families|CBM082]] <!-- ATTENTION: Make sure to replace "nnn" with a three digit fami3 KB (434 words) - 14:14, 18 December 2021
- |GH-G ...both of the corresponding residues of [[GH15]], which belongs to [[clan]] GH-L, are identified as Glu residues, the positions of the catalytic residues6 KB (785 words) - 23:00, 11 July 2023
- ...e>Bamford2020</cite>. Natalie's studies helped in the creation of three GH families ([[Glycoside Hydrolase Family 135|GH135]], [[Glycoside Hydrolase Family 1532 KB (285 words) - 10:41, 29 May 2020
- |GH-x [[Category:Glycoside Hydrolase Families|GH143]]2 KB (297 words) - 15:16, 25 August 2023
- |GH-A ...enzymes, as is typical of [http://www.cazy.org/fam/acc_GH.html#table Clan GH-A], have an asparagine residue preceding the [[general acid/base]] catalyst5 KB (726 words) - 18:10, 27 November 2012
- |{{Hl2}} colspan="2" align="center" |'''Glycoside Hydrolase Family GH 29''' |GH-R9 KB (1,247 words) - 14:19, 18 December 2021
- |GH-A ...d galactose-bound enzyme, respectively <cite>10</cite>. As members of Clan GH-A, Family GH42 enzymes present the catalytic dyad at the C-terminal ends of5 KB (616 words) - 14:16, 18 December 2021
- |GH-x ...The requirement for the metal ion is currently restricted to only three GH families all of which are [[exo]]-α-mannosidases: [[GH38]], [[GH47]] and GH92.6 KB (862 words) - 14:19, 18 December 2021
- ...The position of the [[catalytic nucleophile]] is superimposable with Clan GH-B, whereas the [[general acid/base]] is not. [[Category:Glycoside Hydrolase Families|GH054]]5 KB (638 words) - 02:38, 13 May 2014
- |GH-D ...ate]] <cite>7</cite>. As predicted based on their common clanship in Clan GH-D, [[Glycoside Hydrolase Family 36 (GH36)]] enzymes also operate through th10 KB (1,344 words) - 14:16, 18 December 2021
- |GH-E ...3]], [[GH34]], and [[GH83]] sialidases, which are also members of [[clan]] GH-E (Fig. 3) <cite>Carapito2009 Sogabe2011</cite>. The catalytic machinery is5 KB (676 words) - 09:17, 5 March 2019
- |GH-C Families [[GH11]] and GH12 together form [[clan]] GH-C. The [[catalytic nucleophile]] and the [[general acid/base]] residues of10 KB (1,329 words) - 14:18, 18 December 2021
- ...orting the classification of these phosphorolytic enzymes as one of the GH families. A large conformational change in TIM barrel scaffold was observerd with su [[Category:Glycoside Hydrolase Families|GH112]]4 KB (489 words) - 14:15, 18 December 2021
- |GH-H ...side hydrolase]] family GH77 is a member of the α-amylase [[clans|clan]] [[GH-H]] <cite>Cantarel2009</cite>, together with [[GH13]] and [[GH70]] <cite>Ma10 KB (1,359 words) - 14:20, 18 December 2021
- |GH-A ...ion of the catalytic apparatus in GH127 and GH146 members, enzymes in both families were proposed to hydrolyse arabinofururanosidic bonds through a retaining m4 KB (583 words) - 14:20, 18 December 2021
- |GH-x [[Category:Glycoside Hydrolase Families|GH131]]3 KB (350 words) - 14:19, 18 December 2021
- |GH-x [[Category:Glycoside Hydrolase Families|GH168]]3 KB (382 words) - 12:23, 18 June 2023
- |GH-E .... Enzymes that cleave them in an exo- or endo- acting fashion are found in families [[GH33]], GH34, and [[GH83]] or [[GH53]] respectively.7 KB (1,025 words) - 18:00, 4 January 2023
- |GH-A ...bers of the [[Sequence-based classification of glycoside hydrolases|clan]] GH-A fold, consistent with the classic (α/β)<sub>8</sub> TIM barrel6 KB (760 words) - 14:19, 18 December 2021
- |GH-S ...been biochemically characterized. Later, [[GH144]] is classified into clan GH-S with [[GH162]] based on structural similarity between them <cite>Tanaka206 KB (775 words) - 22:06, 1 February 2024
- |'''Associated GH Families''' [[Category:Carbohydrate Binding Module Families|CBM074]]4 KB (589 words) - 17:39, 22 May 2023
- ...-tools/gh-cbm GH-CBM tool] shows that CBM28s are not associated with other GH family domains. As a typical endo-type (Type B) CBM, CBM28s show the <i>K</ [[Category:Carbohydrate Binding Module Families|CBM028]]6 KB (846 words) - 14:15, 18 December 2021
- |GH-A ...ensive biochemical analysis, GH10 was one of the first glycoside hydrolase families classified by hydrophobic cluster analysis, and was previously known as "Ce4 KB (594 words) - 09:43, 29 July 2015
- |GH-T ...ved sequence regions <cite>Zona2004,Janecek2002</cite>. As far as other GH families are concerned, the family [[GH38]] α-mannosidase from ''Drosophila melanog16 KB (2,110 words) - 03:08, 26 February 2024
- |GH-D ...milies <cite>#Arumapperuma2023</cite>. Family GH13 is one of the two major families of [[glycoside hydrolases]], along with GH13, that contain α-glucosid9 KB (1,124 words) - 22:18, 16 December 2023
- |GH-E ...r different glycoside hydrolase(GH) families: GH33, [[GH34]], and [[GH83]] families are exosialidases while [[GH53]] is an endosialidase <cite>Buschiazzo2008</9 KB (1,152 words) - 17:59, 4 January 2023
- |GH-B ...ta;-glucanase (EC 3.2.1.73). GH7 was one of the first glycoside hydrolase families classified by hydrophobic cluster analysis, and was previously known as "Ce8 KB (1,054 words) - 14:15, 18 December 2021
- ...tic domain is located in the external part of the plasma membrane. Two sub-families have been described for GH72 family members depending on the presence or ab ...sub> barrel similar to that prevailing in other families constituting Clan GH-A <cite>Hurtado-Guerrero2009</cite>. The full length enzyme also harbors a6 KB (724 words) - 14:19, 18 December 2021
- |GH-x [[Category:Glycoside Hydrolase Families|GH101]]3 KB (450 words) - 17:23, 13 May 2020
- |GH-x [[Category:Glycoside Hydrolase Families|GH174]]3 KB (443 words) - 01:48, 26 May 2023
- ...[[GH162]] and [[GH144]] are conserved <cite>Tanaka2024</cite>. A new clan GH-S was created for GH162 and GH144 based on these results <cite>Tanaka2024</ [[Category:Glycoside Hydrolase Families|GH162]]7 KB (996 words) - 20:03, 1 February 2024
- ...([[GH15]], [[GH65]], and [[GH125]]) and [[GH94]]. The members of [[clan]] GH-L and GH95 act on α-linkages, whereas [[GH94]] acts on β-linkage [[Category:Glycoside Hydrolase Families|GH095]]6 KB (915 words) - 14:16, 18 December 2021
- |GH-L ...e>. [[GH15]] and [[GH65]] together constitute glycoside hydrolase [[Clan]] GH-L <cite>Cantarel2009</cite>. [[GH94]] phosphorylases and a [[GH95]] fucosid7 KB (917 words) - 14:18, 18 December 2021
- |GH-x ...he enzyme-bound NADH generates the product. Similar mechanisms are used in families [[GH4]], [[GH109]], [[GH177]], and [[GH179]].5 KB (629 words) - 10:33, 19 December 2023
- |GH-G GH37 enzymes belong to the [[clans|clan]] GH-G.7 KB (1,029 words) - 14:17, 18 December 2021
- |GH-I ...well the chitinases from family GH19 <cite>Monzingo1996</cite>. These five families are sometimes grouped in the "lysozyme superfamily" <cite>Holm1994 Lacombe-6 KB (796 words) - 14:20, 18 December 2021
- |GH-A ...ite>. As a historical note, GH26 was one of the first glycoside hydrolase families classified by sequence analysis, and was previously known as "Cellulase Fam5 KB (727 words) - 14:17, 18 December 2021
- |GH-H ...er with the families [[GH13]] and [[GH77]] enzymes, they form the [[clan]] GH-H.11 KB (1,450 words) - 14:14, 18 December 2021
- |GH-O ...arrel domain (Figure 1) that has led to their classification into [[Clan]] GH-O, together with [[GH116]]. The ''exo''-acting mode-of-action of GH52's is7 KB (960 words) - 14:15, 18 December 2021
- ...Based on the low sequence similarity to GH29, it was suggested that a new GH family be created <cite>Benesova2015</cite>. Sequence homology to [[GH42]] [[Category:Glycoside Hydrolase Families|GH151]]4 KB (506 words) - 04:19, 20 May 2022
- |GH-A ...2001, Tuskan2006</cite>, GH35 members tend to be represented by multi-gene families in plants <cite>Ahn2007, Smith2000, Lazan2004, Ross1994, Tanthanuch2008</ci10 KB (1,320 words) - 14:18, 18 December 2021
- |GH-A GH5 is one of the largest of all CAZy [[glycoside hydrolase]] families. Previously known as "cellulase family A" <cite>Henrissat1989 Gilkes1991</c9 KB (1,163 words) - 14:20, 18 December 2021
- ...tension of, the [http://www.cazy.org/ CAZy database], which "describes the families of structurally-related catalytic and carbohydrate-binding modules (or func ...imensional structure, or other important work which defines catalysis in a GH family or subfamily.10 KB (1,453 words) - 12:28, 4 July 2023