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User:Stefan Janecek

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Stefan Janecek is a research scientist at the Institute of Molecular Biology of the Slovak Academy of Sciences, Bratislava, Slovakia and a teacher at the Department of Biology of the Faculty of Natural Sciences, University of SS. Cyril and Methodius, Trnava, Slovakia.

He is a group leader heading the Laboratory of Protein Evolution.

He is most interested in the enzymes and proteins from the alpha-amylase family - the clan GH-H of glycoside hydrolase families GH13, GH70 and GH77 as well as families GH57 with GH119, and eventually also GH126, especially in their evolution as well as their structure-function and structure-stability relationships. In addition, he is also very interested in bioinformatics studies of starch-binding domains that currently involve fifteen CAZy CBM families: CBM20, CBM21, CBM25, CBM26, CBM34, CBM41, CBM45, CBM48, CBM53, CBM58, CBM68, CBM69, CBM74, CBM82 and CBM83.

Stefan works as a protein bioinfomatician, being engaged especially in the in silico studies. In his close collaboration with experimentalists, they have three amylolytic enzymes used as experimental models: (i) GH13 alpha-amylase from Thermococcus hydrothermalis; (ii) GH57 amylopullulanase from Thermococcus hydrothermalis; and (iii) GH77 amylomaltase from Borrelia burgdorferi. The experimental work is focused on protein design of these enzymes based on bioinformatics analyses.

Stefan is founder and main organiser of the international symposia on the alpha-amylase enzyme family - ALAMYs; for the most recent one, being held in autumn 2019, please click: ALAMY_7.

He is also founder and the Editor-in-Chief of the brand new, open access journal Amylase.

He serves as the Associate Editor of the journal 3Biotech and Managing Editor of the journal Biologia, section Cellular and Molecular Biology, too.